Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Shigekuni Hosogi"'
Autor:
Toma Matsui, Yuki Toda, Haruka Sato, Rina Itagaki, Kazuya Konishi, Anna Moshnikova, Oleg A. Andreev, Shigekuni Hosogi, Yana K. Reshetnyak, Eishi Ashihara
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Dysregulated extracellular pH, the universal feature of tumor, works as an evolutional force to drive dissemination of tumor cells. It is well-established that tumor acidity is associated with tumor growth and metastasis. However, the pH of pre-metas
Externí odkaz:
https://doaj.org/article/ff4230ee58574fc48849bf75c7dc4ddc
Autor:
Yu Yamanoi, Jing Lei, Yasunori Takayama, Shigekuni Hosogi, Yoshinori Marunaka, Makoto Tominaga
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
The chloride channel anoctamin1, upon activation by calcium influx through transient receptor potential vanilloid 3, mediates chloride influx and enhances wound healing in keratinocytes.
Externí odkaz:
https://doaj.org/article/f1639e62bb2745bcba495891d1d7cd87
Autor:
Takashi Nakahari, Chihiro Suzuki, Kotoku Kawaguchi, Shigekuni Hosogi, Saori Tanaka, Shinji Asano, Toshio Inui, Yoshinori Marunaka
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16976 (2023)
Ambroxol (ABX), a frequently prescribed secretolytic agent which enhances the ciliary beat frequency (CBF) and ciliary bend angle (CBA, an index of amplitude) by 30%, activates a voltage-dependent Ca2+ channel (CaV1.2) and a small transient Ca2+ rele
Externí odkaz:
https://doaj.org/article/aab5079ded5047309d8f4b083ef4aeb1
Autor:
Leonardo Puppulin, Shigekuni Hosogi, Hongxin Sun, Kazuhiko Matsuo, Toshio Inui, Yasuaki Kumamoto, Toshinobu Suzaki, Hideo Tanaka, Yoshinori Marunaka
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Understanding the pH changes at cell surfaces is important for understanding the mechanisms of different physiological processes. Here, the authors report on the development of a cell membrane anchored gold nanoparticle for surface enhanced Raman spe
Externí odkaz:
https://doaj.org/article/7bcbf5a216af4a93ac2929ed8085cdd4
Autor:
Leonardo Puppulin, Giuseppe Pezzotti, Hongxin Sun, Shigekuni Hosogi, Takashi Nakahari, Toshio Inui, Yasuaki Kumamoto, Hideo Tanaka, Yoshinori Marunaka
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The typical response to the lowering of plasma Na+ concentration and blood pressure in our body involves the release of aldosterone from the adrenal glands, which triggers the reabsorption of sodium in the kidney. Although the effects of ald
Externí odkaz:
https://doaj.org/article/020ca6996b084291b171f8dff38a6fb5
Autor:
Shigekuni Hosogi, Masahiro Ohsawa, Ikuo Kato, Atsukazu Kuwahara, Toshio Inui, Akio Inui, Yoshinori Marunaka
Publikováno v:
Frontiers in Nutrition, Vol 5 (2018)
Diabetes mellitus is a well-known common disease and one of the most serious social problems in the worldwide. Although various types of drugs are developed, the number of patients suffering from diabetes mellitus is still increasing. Ninjin'yoeito (
Externí odkaz:
https://doaj.org/article/2b42d7102e8a413aa439786aa53c5866
Autor:
Haruka Kogiso, Yukiko Ikeuchi, Masako Sumiya, Shigekuni Hosogi, Saori Tanaka, Chikao Shimamoto, Toshio Inui, Yoshinori Marunaka, Takashi Nakahari
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 3, p 658 (2018)
Sei-hai-to (TJ-90, Qing Fei Tang), a Chinese traditional medicine, increases ciliary beat frequency (CBF) and ciliary bend angle (CBA) mediated via cAMP (3′,5′-cyclic adenosine monophosphate) accumulation modulated by Ca2+-activated phosphodieste
Externí odkaz:
https://doaj.org/article/e9589af729a7460791b38bafe2b8e063
Autor:
Manuela Salerno, Sofia Avnet, Gloria Bonuccelli, Shigekuni Hosogi, Donatella Granchi, Nicola Baldini
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110340 (2014)
Rhabdomyosarcoma is the most frequent soft tissue sarcoma in children and adolescents, with a high rate of relapse that dramatically affects the clinical outcome. Multiagent chemotherapy, in combination with surgery and/or radiation therapy, is the t
Externí odkaz:
https://doaj.org/article/d9c6cbb2033145679140ff3a9a215ce9
Publikováno v:
Cancer Genomics & Proteomics (1109-6535); Mar/Apr2024, Vol. 21 Issue 2, p158-165, 8p
Autor:
Shigekuni Hosogi, Atsukazu KUWAHARA, Yuko KUWAHARA, Saori TANAKA, Chikao SHIMAMOTO, Noriko TAGAWA, Ikuo KATO, Kanji YOSHIMOTO, Wataru AOI, Kazuyuki TAKATA, Hiroaki MIYAZAKI, Naomi NIISATO, Yasuhiro TSUBO, Katsumi YAGI, Takashi NAKAHARI, Yoshinori MARUNAKA
Publikováno v:
Biomedical Research. 44:17-29