Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Shigeki Ohta"'
Autor:
Tomonori Yaguchi, Yutaka Kawakami, Kenji Morii, Takashi Iwata, Akiko Kubo, Yoshitaka Oyamada, Yuki Katoh, Daiki Kato, Shigeki Ohta, Ryosuke Satomi, Yasuhiro Yamamoto, Kota Ouchi, Shin Takahashi, Chikashi Ishioka, Ryo Matoba, Makoto Suematsu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Understanding the mechanisms of non-T cell inflamed tumor microenvironment (TME) and their modulation are important to improve cancer immunotherapies such as immune checkpoint inhibitors. The involvement of various immunometabolisms has re
Externí odkaz:
https://doaj.org/article/421ebcc794d14e4fae08d52bd195b06d
Autor:
Hironobu Okuno, Francois Renault Mihara, Shigeki Ohta, Kimiko Fukuda, Kenji Kurosawa, Wado Akamatsu, Tsukasa Sanosaka, Jun Kohyama, Kanehiro Hayashi, Kazunori Nakajima, Takao Takahashi, Joanna Wysocka, Kenjiro Kosaki, Hideyuki Okano
Publikováno v:
eLife, Vol 6 (2017)
CHARGE syndrome is caused by heterozygous mutations in the chromatin remodeler, CHD7, and is characterized by a set of malformations that, on clinical grounds, were historically postulated to arise from defects in neural crest formation during embryo
Externí odkaz:
https://doaj.org/article/d4a2e98430e14327961d3988ad1c1dcb
Autor:
Yuto Nakanishi, Shigeki Ohta, Takuma Shirai, Yuki Asano, Toyotaka Kozuki, Yuriko Kakehashi, Hironori Mizoguchi, Tomoko Kurotobi, Yotaro Motegi, Kazuhiro Sasabuchi, Junichi Urata, Kei Okada, Ikuo Mizuuchi, Masayuki Inaba
Publikováno v:
International Journal of Advanced Robotic Systems, Vol 10 (2013)
In order to realize more natural and various motions like humans, humanlike musculoskeletal tendon-driven humanoids have been studied. Especially, it is very challenging to design musculoskeletal body structure which consists of complicated bones, re
Externí odkaz:
https://doaj.org/article/a2ab333673d24e7db78242a036828702
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74315 (2013)
Macrophage migration inhibitory factor (MIF) has important roles in supporting the proliferation and/or survival of murine neural stem/progenitor cells (NSPCs), but downstream effectors remain unknown. We show here that MIF robustly increases the exp
Externí odkaz:
https://doaj.org/article/c445ee72f95c4acc9ed8ceb676d6cf47
Autor:
Shigeki Ohta, Yoichi Imaizumi, Yohei Okada, Wado Akamatsu, Reiko Kuwahara, Manabu Ohyama, Masayuki Amagai, Yumi Matsuzaki, Shinya Yamanaka, Hideyuki Okano, Yutaka Kawakami
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16182 (2011)
Epidermal melanocytes play an important role in protecting the skin from UV rays, and their functional impairment results in pigment disorders. Additionally, melanomas are considered to arise from mutations that accumulate in melanocyte stem cells. T
Externí odkaz:
https://doaj.org/article/360cbd18bfe44ad7a4b777094a9f94c6
Publikováno v:
Experimental Dermatology. 32:297-305
Melanoma has been a prototype for cancer immunology research, and the mechanisms of anti-tumor T cell responses have been extensively investigated in patients treated with various immunotherapies. Individual differences in cancer-immune status are de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047471a3d25921d84abe8721b224593d
https://doi.org/10.1111/exd.14741
https://doi.org/10.1111/exd.14741
Autor:
Masahiro Toda, Kazunari Yoshida, Takeshi Kawase, Yutaka Kawakami, Hideyuki Saya, Hideyuki Okano, Eiji Sugihara, Yumi Matsuzaki, Tomonori Yaguchi, Shigeki Ohta, Raita Fukaya
Supplementary Figure S1. Gene expression of CD74 and CXCR4.Supplementary Figure S2. TP53 gene silencing in U87MG and T98G cells. Supplementary Figure S3. Effects of MIF gene silencing on p21 and BAX reporter gene expression in T98G cells.Supplementar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b2dd9858f9d5c1a5cfc8915dab889b
https://doi.org/10.1158/0008-5472.22411203.v1
https://doi.org/10.1158/0008-5472.22411203.v1
Autor:
Masahiro Toda, Kazunari Yoshida, Takeshi Kawase, Yutaka Kawakami, Hideyuki Saya, Hideyuki Okano, Eiji Sugihara, Yumi Matsuzaki, Tomonori Yaguchi, Shigeki Ohta, Raita Fukaya
Tumor-initiating cells thought to drive brain cancer are embedded in a complex heterogeneous histology. In this study, we isolated primary cells from 21 human brain tumor specimens to establish cell lines with high tumorigenic potential and to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::868de4671699e1efae3fa1c0fa6221cf
https://doi.org/10.1158/0008-5472.c.6508176.v1
https://doi.org/10.1158/0008-5472.c.6508176.v1
Autor:
Masahiro Toda, Kazunari Yoshida, Takeshi Kawase, Yutaka Kawakami, Hideyuki Saya, Hideyuki Okano, Eiji Sugihara, Yumi Matsuzaki, Tomonori Yaguchi, Shigeki Ohta, Raita Fukaya
Supplementary materials and methods, Supplementary Table 1, and Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a08cdb86553773f5949a79fcf60c787
https://doi.org/10.1158/0008-5472.22411194.v1
https://doi.org/10.1158/0008-5472.22411194.v1
Autor:
Masahiro Toda, Kazunari Yoshida, Takeshi Kawase, Yutaka Kawakami, Hideyuki Saya, Hideyuki Okano, Eiji Sugihara, Yumi Matsuzaki, Tomonori Yaguchi, Shigeki Ohta, Raita Fukaya
Immunohistochemical study of the mouse brain tumor in therapeutic model by lenti-shMIF.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0024369aa6c76b8281db52f197ef0d6e
https://doi.org/10.1158/0008-5472.22411200.v1
https://doi.org/10.1158/0008-5472.22411200.v1