Zobrazeno 1 - 10
of 456
pro vyhledávání: '"Shigeki KATO"'
Autor:
Yoshio Iguchi, Ryoji Fukabori, Shigeki Kato, Kazumi Takahashi, Satoshi Eifuku, Yuko Maejima, Kenju Shimomura, Hiroshi Mizuma, Aya Mawatari, Hisashi Doi, Yilong Cui, Hirotaka Onoe, Keigo Hikishima, Makoto Osanai, Takuma Nishijo, Toshihiko Momiyama, Richard Benton, Kazuto Kobayashi
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Chemogenetic approaches employing ligand-gated ion channels are advantageous regarding manipulation of target neuronal population functions independently of endogenous second messenger pathways. Among them, Ionotropic Receptor (IR)-mediated
Externí odkaz:
https://doaj.org/article/4f053390d6844f59b01dae87a7a16116
Autor:
Alain Rios, Satoshi Nonomura, Shigeki Kato, Junichi Yoshida, Natsuki Matsushita, Atsushi Nambu, Masahiko Takada, Riichiro Hira, Kazuto Kobayashi, Yutaka Sakai, Minoru Kimura, Yoshikazu Isomura
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Neurons comprising nigrostriatal system play important roles in action selection. However, it remains unclear how this system integrates recent outcome information with current action (movement) and outcome (reward or no reward) information
Externí odkaz:
https://doaj.org/article/3893293cde8b4b989d735851cb5113e5
Autor:
Natsuki Matsushita, Shigeki Kato, Kayo Nishizawa, Masateru Sugawara, Kosei Takeuchi, Yoshiki Miyasaka, Tomoji Mashimo, Kazuto Kobayashi
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102667- (2023)
Summary: We present a protocol to induce Cre-dependent transgene expression in specific cell types in the rat brain, suppressing a leak expression in off-target cells, by using a flip-excision switch system with a unilateral spacer sequence. We descr
Externí odkaz:
https://doaj.org/article/8d52f40bf4104ba8913e91b58717cd97
Autor:
Yuko Terada, Masanobu Akimoto, Hirofumi Sakoda, Shunsuke Yamamoto, Mayuka Kubota, Tomoharu Motoyama, Yo Imanaka, Shogo Nakano, Sohei Ito, Shigeki Kato, Keisuke Ito
Publikováno v:
Foods, Vol 13, Iss 3, p 407 (2024)
Food allergies are a significant health issue worldwide. In many countries, labeling of primary allergens in food products has been made mandatory to ensure consumer safety. In food manufacturing settings, the lateral flow immunoassay (LFI)—based o
Externí odkaz:
https://doaj.org/article/6527eeeac9914a9e8a7ab97178816d0a
Autor:
Yusuke Atsumi, Yasuhiro Oisi, Maya Odagawa, Chie Matsubara, Yoshihito Saito, Hiroyuki Uwamori, Kenta Kobayashi, Shigeki Kato, Kazuto Kobayashi, Masanori Murayama
Publikováno v:
Frontiers in Neural Circuits, Vol 17 (2023)
Despite the importance of postsynaptic inhibitory circuitry targeted by mid/long-range projections (e.g., top-down projections) in cognitive functions, its anatomical properties, such as laminar profile and neuron type, are poorly understood owing to
Externí odkaz:
https://doaj.org/article/ddbac1be61594fa088111fb29e9be2cd
Publikováno v:
iScience, Vol 26, Iss 6, Pp 106985- (2023)
Summary: The insular cortex (insula) is known to play a modulatory role in feeding and drinking. Previous studies have revealed anterior-posterior differences of subcortical projections and roles for the insula, yet the anatomical and functional hete
Externí odkaz:
https://doaj.org/article/6faf61904c2e4b11ac49cdfef160c572
Autor:
Natsuki Matsushita, Shigeki Kato, Kayo Nishizawa, Masateru Sugawara, Kosei Takeuchi, Yoshiki Miyasaka, Tomoji Mashimo, Kazuto Kobayashi
Publikováno v:
Cell Reports: Methods, Vol 3, Iss 2, Pp 100393- (2023)
Summary: The flip-excision switch (FLEX) system with an adeno-associated viral (AAV) vector allows expression of transgenes in specific cell populations having Cre recombinase. A significant issue with this system is non-specific expression of transg
Externí odkaz:
https://doaj.org/article/cb4f42bb636e4b71a25622972aa7bb88
Autor:
Mineki Oguchi, Shingo Tanaka, Xiaochuan Pan, Takefumi Kikusui, Keiko Moriya-Ito, Shigeki Kato, Kazuto Kobayashi, Masamichi Sakagami
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-18 (2021)
In order to validate a previously inferred function of the lateral prefrontal cortex (LPFC)-caudate nucleus (CdN) pathway in humans in inhibitory control and working memory, Oguchi et al used pathway-selective chemogenetic manipulation of neural acti
Externí odkaz:
https://doaj.org/article/72c2b3b4a39f48079b44015afc54d842
Publikováno v:
Frontiers in Systems Neuroscience, Vol 15 (2021)
The dorsal striatum (DS) is a key structure of the basal ganglia circuitry, which regulates various types of learning processes and flexible switching of behavior. Intralaminar thalamic nuclei (ILNs) provide the main source of thalamostriatal inputs
Externí odkaz:
https://doaj.org/article/6a984e9d729e49c3902826e90013cb5f
Autor:
Nobuyuki Sakayori, Shigeki Kato, Masateru Sugawara, Susumu Setogawa, Hotaka Fukushima, Rie Ishikawa, Satoshi Kida, Kazuto Kobayashi
Publikováno v:
Molecular Brain, Vol 12, Iss 1, Pp 1-12 (2019)
Abstract The cerebellum regulates complex animal behaviors, such as motor control and spatial recognition, through communication with many other brain regions. The major targets of the cerebellar projections are the thalamic regions including the ven
Externí odkaz:
https://doaj.org/article/3f35d509b682478aad3d64688f94b90c