Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Shigeki Hongo"'
Autor:
Seiji Shioda, Akira Miyazaki, Tomoko Kanome, Haruaki Kageyama, Shigeko Arita, Takuya Watanabe, Shigeki Hongo
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 297:E474-E482
Leptin is an adipose tissue-derived hormone implicated in atherosclerosis and macrophage foam cell formation. The current study was conducted to examine the effect of leptin on cholesteryl ester accumulation in human monocytes/macrophages. Exogenousl
Autor:
Toshiaki Suguro, Tetsuo Sakai, Shigeki Hongo, Takuya Watanabe, Akira Miyazaki, Shigeko Arita, Yuji Shiraishi
Publikováno v:
Current Medicinal Chemistry. 16:550-563
Human urotensin II (U-II), the most potent vasoconstrictor undecapeptide identified to date, and its receptor (UT) are involved in the pathogenesis of systemic and pulmonary hypertension. Here, we review recent advances in our understanding of the pa
Autor:
Mitsuru Adachi, Takuya Watanabe, Masaharu Nagashima, Yuji Shiraishi, Hiroyuki Itabe, Rina Kato, Shigeki Hongo, Akira Miyazaki, Tsutomu Hirano, Toshiaki Suguro
Publikováno v:
Journal of Hypertension. 26:1955-1965
Objective Our recent studies have indicated that urotensin II, the most potent vasoconstrictor peptide identified to date, potentiates human macrophage foam cell formation and vascular smooth muscle cell proliferation, and its levels are increased in
Autor:
Takuya Watanabe, Tetsuo Sakai, Shinji Koba, Tomoko Kanome, Kae Nishio, Kiyoshi Nose, Akira Miyazaki, Shigeki Hongo, Masayoshi Shichiri, Hidekazu Ota, Kengo Sato, Takashi Katagiri, Youichi Kobayashi, Taka-aki Matsuyama
Publikováno v:
Circulation. 117:638-648
Background— Human salusins, related bioactive polypeptides with mitogenic effects on vascular smooth muscle cells and fibroblasts and roles in hemodynamic homeostasis, may be involved in the origin of coronary atherosclerosis. Macrophage foam cell
Publikováno v:
Hypertension Research. 31:1801-1810
Angiotensin II (Ang II) is known to accelerate the progression of macrophage-driven atherosclerotic lesions. Acyl-CoA:cholesterol acyltransferase-1 (ACAT1) converts intracellular free cholesterol into cholesterol ester (CE) for storage in lipid dropl
Autor:
Tomoko Kanome, Shinji Koba, Akira Miyazaki, Claude R. Benedict, Takashi Katagiri, Rajbabu Pakara, Shigeki Hongo, Takuya Watanabe, Keiko Takahashi
Publikováno v:
Hypertension Research. 29:821-831
Human urotensin-II (U-II) is the most potent vasoactive peptide identified to date, and may be involved in hypertension and atherosclerosis. We investigated the effects of the interactions between U-II or other vasoactive agents and mildly oxidized l
Autor:
Syuusuke Kodate, Toshiaki Suguro, Tamio Hagiwara, Akira Miyazaki, Tomoko Kanome, Shigeki Hongo, Mitsuru Adachi, Yu-Ichiro Sakamoto, Takuya Watanabe, Tsutomu Hirano
Publikováno v:
Hypertension. 46:738-744
Human urotensin II (U-II), the most potent vasoconstrictor peptide identified to date, and its receptor (UT) are involved in hypertension and atherosclerosis. Acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT-1) converts intracellular free choleste
Genomic organization, expression, and comparative analysis of noncoding region of the rat Ndrg4 gene
Publikováno v:
Gene. 324:149-158
Rat Ndrg4 is a member of the NDRG gene family and has been suggested to relate to brain development. The structure of the rat Ndrg4 gene was studied to understand the mechanism for the expression of multiple forms of Ndrg4 protein, which were reveale
Publikováno v:
Developmental Brain Research. 135:55-63
NDRG4, a member of the new NDRG gene family, was originally cloned as a gene that was expressed predominantly in the early postnatal rat brain. To determine whether the NDRG4 protein contributes to differentiation of neural cells, the effect of lower
Autor:
Noriyuki Nakada, Takeshi Ohki, Minoru Takeda, Ryu Takahashi, Takashi Ohashi, Fumiyo Takeda, Shigeki Hongo, Akihiko Maeda
Publikováno v:
The Showa University Journal of Medical Sciences. 13:17-25