Zobrazeno 1 - 10
of 463
pro vyhledávání: '"Shigeki, Sekine"'
Autor:
Shigemasa Takamizawa, Hidekazu Hirano, Atsuo Takashima, Hirokazu Shoji, Toshiharu Hirose, Natsuko Okita, Kouya Shiraishi, Shigeki Sekine, Yasuyuki Takamizawa, Yukihide Kanemitsu, Ken Kato
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Claudin-18 isoform 2 (CLDN18.2) is expressed in multiple cancers and is a promising target for antitumor therapy. However, there is limited knowledge regarding the prevalence and characteristics of CLDN18.2-positive colorectal cancer (CRC
Externí odkaz:
https://doaj.org/article/88e242f5417e4b989d25a2526d810928
Autor:
Wataru Nakamura, Makoto Hirata, Satoyo Oda, Kenichi Chiba, Ai Okada, Raúl Nicolás Mateos, Masahiro Sugawa, Naoko Iida, Mineko Ushiama, Noriko Tanabe, Hiromi Sakamoto, Shigeki Sekine, Akira Hirasawa, Yosuke Kawai, Katsushi Tokunaga, NCBN Controls WGS Consortium, Shin-ichi Tsujimoto, Norio Shiba, Shuichi Ito, Teruhiko Yoshida, Yuichi Shiraishi
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Innovations in sequencing technology have led to the discovery of novel mutations that cause inherited diseases. However, many patients with suspected genetic diseases remain undiagnosed. Long-read sequencing technologies are expected to sig
Externí odkaz:
https://doaj.org/article/7f7b990a881248838189c1889a7e569e
Autor:
Tsutomu Hayashi, Ken Takasawa, Takaki Yoshikawa, Taiki Hashimoto, Shigeki Sekine, Takeyuki Wada, Yukinori Yamagata, Haruhisa Suzuki, Seiichirou Abe, Shigetaka Yoshinaga, Yutaka Saito, Nobuji Kouno, Ryuji Hamamoto
Publikováno v:
Annals of Gastroenterological Surgery, Vol 7, Iss 6, Pp 913-921 (2023)
Abstract Aim Gastrectomy is recommended for patients with early gastric cancer (EGC) because the possibility of lymph node metastasis (LNM) cannot be completely denied. The aim of this study was to develop a discrimination model to select patients wh
Externí odkaz:
https://doaj.org/article/a8f0717fa6984d06993db12cd6e180b0
Autor:
Takayuki Matsumoto, Junji Umeno, Keisuke Jimbo, Masami Arai, Itaru Iwama, Hiroshi Kashida, Takahiro Kudo, Koichi Koizumi, Yasushi Sato, Shigeki Sekine, Shinji Tanaka, Kohji Tanakaya, Kazuo Tamura, Keiji Hirata, Suguru Fukahori, Motohiro Esaki, Hideki Ishikawa, Takeo Iwama, Yasushi Okazaki, Yutaka Saito, Nariaki Matsuura, Michihiro Mutoh, Naohiro Tomita, Takashi Akiyama, Toshiki Yamamoto, Hideyuki Ishida, Yoshiko Nakayama
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 7, Iss 2, Pp 115-125 (2023)
Juvenile polyposis syndrome (JPS) is a rare disease characterized by multiple hamartomatous polyps within the gastrointestinal tract. SMAD4 or BMPR1A is known as a causative gene of JPS. Approximately 75% of newly diagnosed cases have an autosomal-do
Externí odkaz:
https://doaj.org/article/4303d107d2664da9b1128f48062decc5
Autor:
Takahiko Ito, Daisuke Takayanagi, Shigeki Sekine, Taiki Hashimoto, Yoko Shimada, Maiko Matsuda, Masayoshi Yamada, Ryuji Hamamoto, Tomoyasu Kato, Dai Shida, Yukihide Kanemitsu, Narikazu Boku, Takashi Kohno, Atsuo Takashima, Kouya Shiraishi
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Anal squamous cell carcinoma (ASCC) is a rare tumor of the gastrointestinal tract. We aimed to compare the genetic backgrounds and their effect on clinical outcomes between Japanese and Caucasian patients with ASCC. Forty-one patients diagno
Externí odkaz:
https://doaj.org/article/5c62401519fd4daea4e73cec0c6d0bf9
Autor:
Kentaro Kubo, Junya Oguma, Daichi Utsunomiya, Kyohei Kanematsu, Yusuke Fujii, Daisuke Kurita, Koshiro Ishiyama, Seiichiro Abe, Shigeki Sekine, Hiroyuki Daiko
Publikováno v:
Case Reports in Gastroenterology, Vol 16, Iss 3, Pp 569-576 (2022)
Esophageal carcinosarcoma (EC) is a rare malignant tumor, accounting for 0.5–2.8% of esophageal cancers. Most are advanced cancers that are detected as polypoid lesions and are treated with multidisciplinary therapy with a focus on surgery. However
Externí odkaz:
https://doaj.org/article/620f27c9b6514f86a1ed60940fddee97
Autor:
Masako Yamamoto, MD, Yuriko Kawase, MD, PhD, Hirohisa Kishi, MD, PhD, Yuichiro Miyoshi, MD, PhD, Hiroshi Mitsui, MD, PhD, Shigeki Sekine, MD, PhD
Publikováno v:
JAAD Case Reports, Vol 25, Iss , Pp 39-42 (2022)
Externí odkaz:
https://doaj.org/article/feb0003f25c048d798079e24b8b46e58
Autor:
Kenta Seki, Taku Sakamoto, Mai Ego Makiguchi, Naoya Toyoshima, Hiroyuki Takamaru, Masau Sekiguchi, Masayoshi Yamada, Shigeki Sekine, Yukihide Kanemitsu, Yutaka Saito
Publikováno v:
DEN Open, Vol 3, Iss 1, Pp n/a-n/a (2023)
Abstract Various complications of colorectal endoscopic submucosal dissection (ESD) have been reported, including bleeding, penetration, perforation, and coagulation syndrome. However, the occurrence of bowel obstruction after ESD is rare. We report
Externí odkaz:
https://doaj.org/article/aa29f70bedd14feaadf7702f9f380b47
Autor:
Taku Sakamoto, Shintaro Akiyama, Toshiaki Narasaka, Hideo Suzuki, Shigeki Sekine, Yutaka Saito, Kiichiro Tsuchiya
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 6, Iss 2, Pp 92-99 (2022)
Anal squamous cell carcinoma (SCC) is rare, but it has been commonly detected as an invasive cancer. The standard treatment for anal SCC was surgical resection. However, recent medical advances have enabled the standard treatment to be chemoradiother
Externí odkaz:
https://doaj.org/article/bc3c4b50b3d14c06b207087983f6e9f5
Autor:
Sho Tsuyuki, Hideyuki Takeshima, Shigeki Sekine, Yukinori Yamagata, Takayuki Ando, Satoshi Yamashita, Shin Maeda, Takaki Yoshikawa, Toshikazu Ushijima
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Gastric cancers can develop even after Helicobacter pylori (H. pylori) eradication in 0.2–2.9% cases per year. Since H. pylori is reported to directly activate or inactivate cancer-related pathways, molecular profiles of gastric cancers wi
Externí odkaz:
https://doaj.org/article/c83d7a495e904d40ad3074453a8b9f5a