Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Shigeki, Inui"'
Publikováno v:
Allergology International, Vol 71, Iss 3, Pp 420-422 (2022)
Externí odkaz:
https://doaj.org/article/651f4345bf61432cba8f6ed99361cf42
Publikováno v:
Cells, Vol 11, Iss 2, p 202 (2022)
Recently, extracellular vesicle (EV)-mediated cell differentiation has gained attention in developmental biology due to genetic exchange between donor cells and recipient cells via transfer of mRNA and miRNA. EVs, also known as exosomes, play a role
Externí odkaz:
https://doaj.org/article/a1b753821666443d96b6d58ffd11bce4
Extracellular acidity is a hallmark of cancers and is independent of hypoxia. Because acidity potentiates malignant phenotypes, therapeutic strategies that enhance the targeting of oncogenic mechanisms in an acidic microenvironment should be effectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1a08e96e005b03beccfd99f2c55e9a
https://doi.org/10.1158/1535-7163.c.6537589.v1
https://doi.org/10.1158/1535-7163.c.6537589.v1
Supplementary Figure S2, related to Figure 2. Systemic buffering attenuates the anti-cancer effect of phenformin on B16F10 cells in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1bb55a9c0f144b2cc7830b16e6adbe
https://doi.org/10.1158/1535-7163.22504018.v1
https://doi.org/10.1158/1535-7163.22504018.v1
Supplementary Figure S3, related to Figure 3. OXPHOS-inhibition causes the activation of caspase-dependent apoptosis at an acidic pHe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de48bf67634b9f51f86d0ca6eb6ed30
https://doi.org/10.1158/1535-7163.22504015.v1
https://doi.org/10.1158/1535-7163.22504015.v1
Supplementary manuscript including supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f331a746b937b87e4e6139a0245545
https://doi.org/10.1158/1535-7163.22504024
https://doi.org/10.1158/1535-7163.22504024
Supplementary Figure S4, related to Figure 4. Intracellular Ca2+ level is increased in melanoma cells after treatment with OXPHOSi at an acidic pHe, leading to cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eed916477d619aa5211da5d9e841e94
https://doi.org/10.1158/1535-7163.22504012
https://doi.org/10.1158/1535-7163.22504012
Supplementary Figure S1, related to Figure 1. pHe is a threshold that modulates the cytotoxicity of OXPHOSi on melanoma cells in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::832e77ffd768c17df3744579fc78c061
https://doi.org/10.1158/1535-7163.22504021.v1
https://doi.org/10.1158/1535-7163.22504021.v1
Supplementary Figure S5, related to Figure 5. ROS scavenging synergizes with the cytotoxicity enhancement of OXPHOSi elicited by acidity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033f4f6bd4db3261199d91f94f9d0c67
https://doi.org/10.1158/1535-7163.22504009.v1
https://doi.org/10.1158/1535-7163.22504009.v1