Zobrazeno 1 - 10
of 442
pro vyhledávání: '"Shigekazu, Nagata"'
Autor:
Stephanie Guillet, Tomi Lazarov, Natasha Jordan, Bertrand Boisson, Maria Tello, Barbara Craddock, Ting Zhou, Chihiro Nishi, Rohan Bareja, Hairu Yang, Frederic Rieux-Laucat, Rosa Irene Fregel Lorenzo, Sabrina D Dyall, David Isenberg, David D'Cruz, Nico Lachmann, Olivier Elemento, Agnes Viale, Nicholas D Socci, Laurent Abel, Shigekazu Nagata, Morgan Huse, W Todd Miller, Jean-Laurent Casanova, Frédéric Geissmann
Publikováno v:
eLife, Vol 13 (2024)
Systemic lupus erythematosus (SLE) is an autoimmune disease, the pathophysiology and genetic basis of which are incompletely understood. Using a forward genetic screen in multiplex families with SLE, we identified an association between SLE and compo
Externí odkaz:
https://doaj.org/article/bbeacfc654b64900aa3479d5ae42195e
Autor:
Shigekazu NAGATA
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences, Vol 100, Iss 1, Pp 1-14 (2023)
In the late 1970s, crude interferon samples were found to exhibit anti-tumour activity. This discovery led to the interferon as a “magic drug” for cancer patients. Many groups, including those in Tokyo, Zurich, and San Francisco, attempted to ide
Externí odkaz:
https://doaj.org/article/2827b54a5236447a83e3f886dae48f91
Autor:
Calianese, David C., Tomoyasu Noji, Sullivan, Jennifer A., Schoch, Kelly, Shashi, Vandana, McNiven, Vanda, Ramos, Luiza Lorena Pires, Jordanova, Albena, Kárteszi, Judit, Hiroshi Ishikita, Shigekazu Nagata
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/29/2024, Vol. 121 Issue 44, p1-11, 21p
Autor:
Satoshi Omori, Misato Tsugita, Yasuto Hoshikawa, Masanobu Morita, Fumiya Ito, Shin-Ichiro Yamaguchi, Qilin Xie, Osamu Noyori, Tomoya Yamaguchi, Ayato Takada, Tatsuya Saitoh, Shinya Toyokuni, Hisaya Akiba, Shigekazu Nagata, Kengo Kinoshita, Masafumi Nakayama
Publikováno v:
Cell Reports, Vol 34, Iss 6, Pp 108734- (2021)
Summary: Macrophage recognition and phagocytosis of crystals is critical for the associated fibrosis and cancer. Of note, multi-walled carbon nanotubes (MWCNTs), the highly representative products of nanotechnology, induce macrophage NLRP3 inflammaso
Externí odkaz:
https://doaj.org/article/c7b014b102d843bda38a9296ef0a0636
Autor:
Shigekazu NAGATA
Publikováno v:
Proceedings of the Japan Academy, Series B Physical & biological sciences; 2024, Vol. 100 Issue 1, p1-8, 8p
Autor:
Takaharu Sakuragi, Shigekazu Nagata
Publikováno v:
Nature Reviews Molecular Cell Biology.
Autor:
Takaharu Sakuragi, Shigekazu Nagata
Publikováno v:
Nature Reviews Molecular Cell Biology.
Autor:
Yuta Ryoden, Shigekazu Nagata
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biologyREFERENCES. 44(10)
Extracellular ATP released from necrotic cells in inflamed tissues activates the P2X7 receptor, stimulates the exposure of phosphatidylserine, and causes cell lysis. Recent findings indicated that XK, a paralogue of XKR8 lipid scramblase, forms a com
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Plasma membranes are composed of a lipid bilayer in which phosphatidylserine (PtdSer) is confined to the inner leaflet by the action of flippase that translocates PtdSer from the outer to inner leaflets. Two P4-ATPases (ATP11A and ATP11C
Publikováno v:
The Journal of biological chemistry. 298(11)
Phospholipids are asymmetrically distributed between the lipid bilayer of plasma membranes in which phosphatidylserine (PtdSer) is confined to the inner leaflet. ATP11A and ATP11C, type IV P-Type ATPases in plasma membranes, flip PtdSer from the oute