Zobrazeno 1 - 10
of 151
pro vyhledávání: '"Shigekatsu KOHNO"'
Autor:
Tomohiko Sekioka, Michiaki Kadode, Masanori Fujii, Kazuhito Kawabata, Takashi Abe, Michiaki Horiba, Shigekatsu Kohno, Takeshi Nabe
Publikováno v:
Allergology International, Vol 64, Iss 4, Pp 351-358 (2015)
Background: The expression and functional role of CysLT2 receptors in asthma have not been clarified. In this study, we evaluated CysLT2 receptors expression, and effects of CysLT2-and CysLT1/2-receptor antagonists on antigen-induced bronchoconstrict
Externí odkaz:
https://doaj.org/article/4c0e8f3b3f78477189689b4934ff26ae
Publikováno v:
Allergology International, Vol 58, Iss 2, Pp 171-178 (2009)
Background: Japanese cedar pollen-induced allergic rhinitis in a guinea pig model clearly induced not only sneezing but also biphasic nasal blockage. To date, there have only been a few reports on models of murine allergic rhinitis which clearly show
Externí odkaz:
https://doaj.org/article/fd8d887d68ec4ae988b0febfd195e895
Autor:
Takeshi Nabe, Kayoko Kubota, Nobuaki Mizutani, Masanori Fujii, Tetsuya Terada, Hiroshi Takenaka, Shigekatsu Kohno
Publikováno v:
Allergology International, Vol 57, Iss 4, Pp 419-427 (2008)
Background: As a non-injection route for immunotherapy, local nasal immunotherapy has been examined in allergic rhinitis patients. However, it is unclear how the immunotherapy affects sneezing, biphasic nasal blockage and nasal hyperresponsiveness. T
Externí odkaz:
https://doaj.org/article/4cc3eeba361741d09bec95e18d64e322
Autor:
Nobuaki Mizutani, Takeshi Nabe, Yasuyoshi Ohtani, Hai Yan Han, Masanori Fujii, Shin Yoshino, Teruhisa Hirayama, Shigekatsu Kohno
Publikováno v:
Journal of Pharmacological Sciences, Vol 105, Iss 3, Pp 291-297 (2007)
It has been hypothesized that air pollution has played a role in the increase in allergy prevalence. However, it remains unclear what exact roles are played by polycyclic aromatic hydrocarbons (PAHs), which are encountered in the environment in the f
Externí odkaz:
https://doaj.org/article/2c32ee09c79344c4bf1295129efe890a
Autor:
Hai Yan Han, Takeshi Nabe, Nobuaki Mizutani, Masanori Fujii, Tetsuya Terada, Hiroshi Takenaka, Shigekatsu Kohno
Publikováno v:
Journal of Pharmacological Sciences, Vol 105, Iss 3, Pp 251-257 (2007)
To elucidate the mechanisms underlying nasal symptoms in patients with aspirin hypersensitivity, we evaluated the effects of orally administered non-steroidal anti-inflammatory drugs (NSAIDs) on the nasal patency of guinea pigs with cedar pollen–in
Externí odkaz:
https://doaj.org/article/61af8e9e15fb4a9690a377e26824d732
Publikováno v:
Journal of Pharmacological Sciences, Vol 104, Iss 3, Pp 243-251 (2007)
Itching is the most important symptom in atopic dermatitis because the persistent scratching in response to itching aggravates the disease. However, the etiologic mechanisms of itching in atopic dermatitis remain uncertain. HR-1 hairless mice fed a s
Externí odkaz:
https://doaj.org/article/8bb7dd7e8a1441b7b42872f797b8bb01
Publikováno v:
Journal of Pharmacological Sciences, Vol 98, Iss 4, Pp 380-387 (2005)
We previously reported that when Japanese cedar pollen was prophylactically p.o. administered before a sensitization stage in a guinea-pig model of allergic rhinitis, pollen-induced nasal blockage was suppressed. In this study, we evaluated whether t
Externí odkaz:
https://doaj.org/article/3707b79fcc514d9e9f4b5f74c460504a
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 4, Pp 437-445 (2003)
ABSTRACT: Whether a state of nasal hyperresponsiveness influences antigen-induced biphasic nasal blockage and sneezing were examined using a guinea pig model of allergic rhinitis. Sensitized animals were challenged with an antigen, Japanese cedar pol
Externí odkaz:
https://doaj.org/article/7e35a61b02cd47f8bdf42fdc343181ab
Autor:
Kazuhiro Fuchibe, Takeshi Nabe, Masanori Fujii, Nobuaki Mizutani, Kiichiro Danno, Akihide Koda, Shigekatsu Kohno
Publikováno v:
Journal of Pharmacological Sciences, Vol 93, Iss 1, Pp 47-54 (2003)
ABSTRACT: To develop an allergic dermatitis model showing persistent scratching in mice, toluene-2,4-diisocyanate (TDI) was repeatedly painted onto the skin of hairless HR-1 mice, and induction of itch-associated scratching behavior was observed. Whe
Externí odkaz:
https://doaj.org/article/71a217e6fa9c4348aef7cbb74a0628d0
Autor:
Takeshi Nabe, Naoki Shinoda, Kazunori Yamashita, Masahiro Yamada, Hideki Yamamura, Shigekatsu Kohno
Publikováno v:
Allergology International, Vol 46, Iss 4, Pp 261-267 (1997)
The majority of cases of allergic asthma in experimental animals have been provoked by inhalation with mist antigen. Because of the inherent inability of some species to breathe through the mouth, including guinea pigs, mice and rats, an upper airway
Externí odkaz:
https://doaj.org/article/40061862854e4949a4c71d51f0a1a199