Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Shigehisa, Kawata"'
Autor:
Kunihiro Ohta, Shu-ichi Hashimoto, Chika Koyama, Ke-Yi Lin, Hitomi Masuda, Yukoh Nakazaki, Atsushi Sawada, Kenjiro Asagoshi, Tomoaki Uchiki, Kanako Tamai, Kohei Kurosawa, Shigehisa Kawata, Takashi Yabuki, Goh Sasaki, Aki Takaiwa, Shunsuke Miyai, Naoki Takahashi, Hidetaka Seo
Publikováno v:
Cellular and Molecular Immunology
Monoclonal antibodies (mAbs) are widely utilized as therapeutic drugs for various diseases, such as cancer, autoimmune diseases, and infectious diseases. Using the avian-derived B cell line DT40, we previously developed an antibody display technology
Autor:
Junko Tokumoto, Michiko Saito, Daichi Nagahara, Mitsuko Ishihara-Sugano, Nobuhiko Hoshi, Megumi Danjo, Eiichi Akahoshi, Takashi Tanida, Hiroshi Kitagawa, Shigehisa Kawata, Ken Tasaka, Youhei Mantani, Mitsuhiro Kawata, Toshifumi Yokoyama, Yoshiaki Tabuchi
Publikováno v:
Journal of Applied Toxicology. 34:117-126
Fetal exposure to dioxins and related compounds is known to disrupt normal development of the midbrain dopaminergic system, which regulates behavior, cognition and emotion. The toxicity of these chemicals is mediated mainly by aryl hydrocarbon recept
Autor:
Yasushi Yatabe, Kohei Yokoi, Yoshitaka Sekido, Koji Kawaguchi, Makiko Fujii, Hideki Murakami, Toyoaki Hida, Shigehisa Kawata, Tetsuo Taniguchi, Masafumi Ito, Noriyasu Usami, Yuichi Ueda, Takayuki Fukui, Yoshitsugu Horio, Yutaka Kondo, Hirotaka Osada
Publikováno v:
Carcinogenesis. 30:1097-1105
Malignant pleural mesothelioma (MPM) is an aggressive neoplasm associated with asbestos exposure. Although expression and activation of receptor tyrosine kinases (RTKs), including MET, have been reported in most MPM, specific RTK inhibitors showed le
Autor:
Jun Suzuki, Shigehisa Kawata, Keiichiro Yogo, Tomoyuki Shishido, Norihiro Ishida-Kitagawa, Megumi Mizutamari, Masahiro Maruoka, Parmjit S. Jat
Publikováno v:
Biochemical and Biophysical Research Communications. 350:97-104
Osteoclast precursor cells (OPCs) have previously been established from bone marrow cells of SV40 temperature-sensitive T antigen-expressing transgenic mice. Here, we use retrovirus-mediated gene transfer to conditionally immortalize OPCs by expressi
Autor:
Takashi, Tanida, Ken, Tasaka, Eiichi, Akahoshi, Mitsuko, Ishihara-Sugano, Michiko, Saito, Shigehisa, Kawata, Megumi, Danjo, Junko, Tokumoto, Youhei, Mantani, Daichi, Nagahara, Yoshiaki, Tabuchi, Toshifumi, Yokoyama, Hiroshi, Kitagawa, Mitsuhiro, Kawata, Nobuhiko, Hoshi
Publikováno v:
Journal of applied toxicology : JAT. 34(2)
Fetal exposure to dioxins and related compounds is known to disrupt normal development of the midbrain dopaminergic system, which regulates behavior, cognition and emotion. The toxicity of these chemicals is mediated mainly by aryl hydrocarbon recept
Autor:
Jun Suzuki, Tomoyuki Shishido, Machi Fukuda, Tatsuo Takeya, Shigehisa Kawata, Masahiro Maruoka, Kubo Yoko
Publikováno v:
Journal of biotechnology. 126(4)
Conventional stable protein expression systems using mammalian cells include a time-consuming step of antibiotic resistance-based cell cloning. Here, we report a rapid flow cytometry-based method for the collection of retrovirus vector-infected Chine
Autor:
Stephen P. Goff, Jun Suzuki, Shigehisa Kawata, Noriko Hirao, Tomoyuki Shishido, Katsuko Tani, Seiichi Sato, Tatsuo Takeya, Masahiro Maruoka, Kayo Yoshida
Publikováno v:
FEBS Letters. (14):2986-2990
In previous work we showed that Abl interactor 1 (Abi-1), by linking enzyme and substrate, promotes the phosphorylation of Mammalian Enabled (Mena) by c-Abl. To determine whether this mechanism extends to other c-Abl substrates, we used the yeast two