Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Shigehiro KOKUBU"'
Autor:
Masayuki Ohta, Naoya Murashima, Tetsuji Ohyama, Tomoharu Yoshida, Shozo Hirota, Hirofumi Kawanaka, Makoto Hashizume, Shinichi Nakamura, Fumio Chikamori, Susumu Eguchi, Takashi Tajiri, Katsutoshi Obara, Shigehiro Kokubu
Publikováno v:
DEN Open, Vol 2, Iss 1, Pp n/a-n/a (2022)
Abstract Objectives The diverse treatments available for portal hypertension require specialized knowledge of hemodynamics and include endoscopic treatments, interventional radiology (IVR), and surgery. The Japan Society for Portal Hypertension has d
Externí odkaz:
https://doaj.org/article/c66e5d3a6d8d4d209e8276a274f20677
Autor:
Eri Sagawa, Hironao Okubo, Hitoshi Ando, Yushi Sorin, Ryo Kanazawa, Eisuke Nakadera, Hiroo Fukada, Shigehiro Kokubu, Akihisa Miyazaki
Publikováno v:
Journal of Pharmacological Sciences, Vol 139, Iss 4, Pp 373-376 (2019)
To investigate the relationship between the exposure and efficacy of tolvaptan, we measured pharmacokinetics of total drug at 7 days after repeated doses of 3.75 mg/day tolvaptan in 16 patients with hepatic edema. Nine patients (56.3%) were responder
Externí odkaz:
https://doaj.org/article/df7951eb884045a784ff180e7de1f727
Autor:
Hironao Okubo, Hitoshi Ando, Kei Ishizuka, Ryuta Kitagawa, Shoki Okubo, Hiroaki Saito, Shigehiro Kokubu, Akihisa Miyazaki, Kenichi Ikejima, Shuichiro Shiina, Akihito Nagahara
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229772 (2020)
BACKGROUND:Fatigue is a common adverse event during lenvatinib treatment in patients with hepatocellular carcinoma. One mechanism contributing to development of fatigue might involve abnormal adenosine triphosphate synthesis that is caused by carniti
Externí odkaz:
https://doaj.org/article/6265dca225ab45c8982a1ca22733884f
Autor:
Kento Imajo, Yusuke Saigusa, Takashi Kobayashi, Koki Nagai, Shinya Nishida, Nobuyoshi Kawamura, Hiroyoshi Doi, Michihiro Iwaki, Asako Nogami, Yasushi Honda, Takaomi Kessoku, Yuji Ogawa, Hiroyuki Kirikoshi, Satoshi Yasuda, Hidenori Toyoda, Hideki Hayashi, Shigehiro Kokubu, Daisuke Utsunomiya, Hirokazu Takahashi, Shinichi Aishima, Beom Kyung Kim, Nobuharu Tamaki, Satoru Saito, Masato Yoneda, Rohit Loomba, Atsushi Nakajima
Publikováno v:
Hepatology Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea89316a42742e6af55fd6489490f6b4
https://doi.org/10.1111/hepr.13927
https://doi.org/10.1111/hepr.13927
Autor:
Michio Saeki, Hironao Okubo, Yusuke Takasaki, Eisuke Nakadera, Yuka Fukuo, Hiroo Fukada, Yuta Hotchi, Hitoshi Maruyama, Shigehiro Kokubu, Shuichiro Shiina, Akihito Nagahara, Kenichi Ikejima
Publikováno v:
Journal of Clinical Medicine; Volume 12; Issue 7; Pages: 2662
This study investigated the impact of partial splenic embolization (PSE) on portal hypertensive gastropathy (PHG). We retrospectively analyzed endoscopic findings and the portal venous system of 31 cirrhotic patients with PHG. The improved group was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6002a355a31f297446f80030d6097d46
Autor:
Haruki Uojima, Xue Shao, Yoshiaki Tanaka, Naohisa Wada, Shuichiro Iwasaki, Kosuke Kubota, Takahide Nakazawa, Yusuke Hara, Wasaburo Koizumi, Shigehiro Kokubu, Hisashi Hidaka, Yuhsaku Kanoh, Akitaka Shibuya
Publikováno v:
Hepatology Research. 50:1083-1090
AIM Lenvatinib is an oral, multitargeted, tyrosine kinase inhibitor, which suppress tumor angiogenesis and tumor progression. It was non-inferior to sorafenib in overall survival in untreated advanced hepatocellular carcinoma (HCC). Sorafenib had a b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a250bfdb5b7ce5bdb6b547aa1d1af0b0
https://doi.org/10.1111/hepr.13531
https://doi.org/10.1111/hepr.13531
Autor:
Kento Imajo, Yusuke Saigusa, Takashi Kobayashi, Koki Nagai, Shinya Nishida, Nobuyoshi Kawamura, Michihiro Iwaki, Yasushi Honda, Takaomi Kessoku, Yuji Ogawa, Hiroyuki Kirikoshi, Satoshi Yasuda, Hidenori Toyoda, Hideki Hayashi, Hiroyoshi Doi, Shigehiro Kokubu, Daisuke Utsunomiya, Hirokazu Takahashi, Shinichi Aishima, Satoru Saito, Masato Yoneda, Atsushi Nakajima
Publikováno v:
Journal of Hepatology. 77:S430-S431
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c043048fb41f325d5fd2649e3dc9481
https://doi.org/10.1016/s0168-8278(22)01196-5
https://doi.org/10.1016/s0168-8278(22)01196-5
Autor:
Tomoharu Yoshida, Shozo Hirota, Susumu Eguchi, Takashi Tajiri, Shin-ichi Nakamura, Shigehiro Kokubu, Masayuki Ohta, Fumio Chikamori, Tetsuji Ohyama, Katsutoshi Obara, Hirofumi Kawanaka, Naoya Murashima, Makoto Hashizume
Publikováno v:
DEN Open. 2
The diverse treatments available for portal hypertension require specialized knowledge of hemodynamics and include endoscopic treatments, interventional radiology (IVR), and surgery. The Japan Society for Portal Hypertension has developed the skill q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e959622c84d2600b4467395172da5d8
https://doi.org/10.1002/deo2.74
https://doi.org/10.1002/deo2.74
Autor:
Yoshiaki Tanaka, Haruki Uojima, Akitaka Shibuya, Wasaburo Koizumi, Satoshi Tanabe, Takahide Nakazawa, Hisashi Hidaka, Xue Shao, Shuichiro Iwasaki, Shigehiro Kokubu, Naohisa Wada, Kousuke Kubota
Publikováno v:
Hepatology research : the official journal of the Japan Society of HepatologyREFERENCES. 50(11)
AIM Esophageal variceal ligation (EVL) is usually carried out to decrease the risk of hemorrhage. Several complications have been reported with the procedure, including bleeding from ligation-induced esophageal ulcers or heartburn. However, there is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d07aadca11ff3b8105a605e9720e26
https://pubmed.ncbi.nlm.nih.gov/32838474
https://pubmed.ncbi.nlm.nih.gov/32838474
Autor:
Katsutoshi Obara, Jun Koizumi, Norihito Watanabe, Seiichiro Kojima, Naoya Murashima, Shoichi Matsutani, Shigehiro Kokubu
Publikováno v:
Hepatology Research. 48:244-254
Aim To investigate the current status of portal vein thrombosis (PVT) in Japan, the Clinical Research Committee of the Japan Society of Portal Hypertension conducted a questionnaire survey. Methods A questionnaire survey of 539 cases of PVT over the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a7b22414898a710e8332c403e437573
https://doi.org/10.1111/hepr.12983
https://doi.org/10.1111/hepr.12983