Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Shigeharu, Myou"'
Autor:
Toshiyuki Kita, Masaki Fujimura, Shigeharu Myou, Kazuyoshi Watanabe, Yuko Waseda, Shinji Nakao
Publikováno v:
Allergology International, Vol 58, Iss 2, Pp 267-275 (2009)
Background: Phosphodiesterase 4 selective inhibitor may prevent airway inflammation and remodeling. Objective: The aim of this study was to investigate the effects of KF19514, a phosphodiesterase 4 and 1 dual inhibitor, on chronic airway inflammation
Externí odkaz:
https://doaj.org/article/499f8ee304064d2c9fda12c2d5809d71
Autor:
Johsuke Hara, Masaki Fujimura, Shigeharu Myou, Toshiyuki Kita, Miki Abo, Nobuyuki Katayama, Shiho Furusho, Kouichi Nobata, Yoshitaka Oribe, Hideharu Kimura, Takashi Sone, Yuko Waseda, Yukari Ichikawa, Tomoyuki Araya, Noriyuki Ohkura, Shunichi Tamori, Hazuki Takato, Yuichi Tambo, Yoriko Herai, Akihiro Hori, Masahide Yasui, Kazuo Kasahara, Shinji Nakao
Publikováno v:
Allergology International, Vol 57, Iss 3, Pp 211-217 (2008)
Background: 30–80% of outgrown asthma subjects develop symptoms again later in life. We investigated inflammation and function of lower airway in adolescents with former asthma. Methods: 326 never-smoking young adults (mean age 24.0 years) were int
Externí odkaz:
https://doaj.org/article/b1f8e4f3f94a495890553a0fdb269d63
Publikováno v:
Allergology International, Vol 53, Iss 3, Pp 211-217 (2004)
Bronchial asthma is a chronic inflammatory disease of the conducting airways. Current asthma treatment guidelines recommend inhaled corticosteroids (ICS) as the first-line maintenance therapy for mild to severe persistent asthma, because ICS are the
Externí odkaz:
https://doaj.org/article/750adc77f4cd4d00b87caca6a3ea9d8a
Autor:
Hiroki Yamamoto, Shigeharu Myou, Kouichi Nobata, Takashi Ishiguro, Yoshihisa Ishiura, Haruhiko Ogawa, Masaki Fujimura
Publikováno v:
Arzneimittelforschung. 58:297-302
– “Atopic cough” is a new clinical entity that presents with isolated chronic bronchodilator-resistant cough accepted in the Japanese Respiratory Society Guidelines for Management of Cough. The essential features are eosinophilic tracheobronchi
Autor:
Noriaki Kurimoto, Shigeharu Myou, Tatsuki Hirose, Masaki Fujimura, Yoshitaka Oribe, Toshiyuki Kita, Shinji Nakao, Takashi Sone, Kanako Inuzuka
Publikováno v:
Journal of Bronchology & Interventional Pulmonology. 17:301-306
金沢大学医薬保健研究域医学系
Background and Objective: The purpose of this study was to evaluate the relationship between the wall structure assessed by using endobronchial ultrasonography (EBUS) and bronchial hyperresponsiveness i
Background and Objective: The purpose of this study was to evaluate the relationship between the wall structure assessed by using endobronchial ultrasonography (EBUS) and bronchial hyperresponsiveness i
Autor:
Masahide Yasui, Yoshitaka Oribe, Kazuo Kasahara, Akihito Ueda, Toshiyuki Kita, Masaki Fujimura, Johsuke Hara, Noriyuki Ohkura, Shigeharu Myou
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 177:585-592
We hypothesized that cough stress of the airway wall results in a self-perpetuating cough-reflex cycle in which antigen-induced increase in cough-reflex sensitivity results in pathologic cough, and the cough in turn further amplifies cough-reflex sen
Autor:
Kazuo Kasahara, Masaki Fujimura, Yuko Waseda, Johsuke Hara, Noriyuki Ohkura, Yoriko Herai, Takashi Sone, Masahide Yasui, Miki Abo, Shigeharu Myou, Shiho Furusho, Yoshitaka Oribe
Publikováno v:
International Archives of Allergy and Immunology. 140:327-333
Background: It has been reported that nasal allergy influences the lower airway inflammation and functions. We elucidated whether nasal allergy would contribute to lower airway inflammation and functions. Methods: 266 subjects aged 21–39 years were
Publikováno v:
Cough (London, England)
金沢大学大学院医学系研究科機能再生学
Background Cough variant asthma (CVA) is a cause of chronic cough and a precursor of typical asthma. We retrospectively examined the longitudinal change in bronchial responsiveness and cough
Background Cough variant asthma (CVA) is a cause of chronic cough and a precursor of typical asthma. We retrospectively examined the longitudinal change in bronchial responsiveness and cough
Autor:
Anissa Lambertino, Jonathan Learoyd, Xiangdong Zhu, Shigeharu Myou, Evan Boetticher, Angelo Y. Meliton, Masaaki Sano, Nilda M. Munoz, Alan R. Leff
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 33:65-70
We examined the role of phosphoinositide 3-kinase (PI3K) in integrin-mediated eosinophil adhesion. Deltap85, a dominant-negative form of the class IA PI3K adaptor subunit, was fused to an HIV-TAT protein transduction domain (TAT-Deltap85). Recombinan
Autor:
Toshiyuki Kita, Nobuyuki Katayama, Masaki Fujimura, Yoshitaka Oribe, Shinji Nakao, Shigeharu Myou, Johsuke Hara, Masaru Nishitsuji
Publikováno v:
Clinical Experimental Allergy. 35:262-267
Summary Background Gastrooesophageal reflux (GER) is a frequent cause of chronic cough. Several investigators have indicated that inhibitors of H+K+ATPase (proton pump inhibitors; PPIs) could relieve coughing via inhibition of acid reflux. However, w