Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shigefumi TAKEDA"'
Autor:
Yutaka MATSUZAKI, Tamae MATSUZAKI, Hiromasa ONO, Sachiko KOGUCHI, Shuichi TAKEDA, Shigefumi TAKEDA, Shuji FUNO, Masaki ABURADA, Eikichi HOSOYA, Tsutomu OYAMA
Publikováno v:
YAKUGAKU ZASSHI. 111:531-537
The absorption and excretion of gomisin A (TJN-101) in rats whose livers were injured by carbon tetrachloride (CCl4) were investigated. After intravenous administration of TJN-101 at a dose of 5 mg/kg, the terminal elimination half-life was 1.5 h in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a267583b8d43248c5080d8687f97ff4c
https://doi.org/10.1248/yakushi1947.111.9_531
https://doi.org/10.1248/yakushi1947.111.9_531
Autor:
Humito Karakida, Takuji Yamaguchi, Yukinobu Ikeya, Masaki Aburada, Shigefumi Takeda, Mitsuo Tunakawa, Kouin Toda
Publikováno v:
Biologicalpharmaceutical bulletin. 27(7)
We studied the cognitive improving and cerebral protective constituents in the roots of Polygala tenuifolia WILLDENOW, a well-known Chinese traditional medicine prescribed for amnesia, neurasthenia, palpitation, noctural emission and insomnia. Tenuif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0533195178ab7f53ffdae4f556eff94d
https://pubmed.ncbi.nlm.nih.gov/15256744
https://pubmed.ncbi.nlm.nih.gov/15256744
Autor:
Junsuke Tanaka, Mamoru Yamashita, Takashi Kurihara, Masatomo Yamashita, Kyoji Chagi, Yasunori Takeda, Shigefumi Takeda, Yuichi Fujii
Publikováno v:
The Journal of toxicological sciences. 22(5)
The dog has been used as an experimental animal in emesis research. In this study, we analyzed the emetic effects of ipecac syrup using a smaller animal, the ferret, and compared its response to that of the dog. Dogs and ferrets were divided into 4 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7c7ff290c6f71c4a661f432d8104ac
https://pubmed.ncbi.nlm.nih.gov/9442450
https://pubmed.ncbi.nlm.nih.gov/9442450
Autor:
Masaaki Nomura, Kenichi Miyamoto, Kazuhiko Sudo, Yuichi Fujii, Yumiko Ohtaki, Ryosuke Sakai, Shigefumi Takeda, Shinya Wakusawa, Fujiko Sanae
Publikováno v:
Japanese journal of pharmacology. 57(1)
We examined the effects of gomisin A on tumor promotion in the liver after a short-term feeding of 3'-methyl-4-dimethylaminoazobenzene (3'-MeDAB) to rats, compared with the effects of phenobarbital. Male Donryu rats were fed ad libitum a diet contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e73e0f69411a2eaa3e8e7a63feca93
https://pubmed.ncbi.nlm.nih.gov/1800800
https://pubmed.ncbi.nlm.nih.gov/1800800
Autor:
Masaki Aburada, Seiji Morisawaz, Shoji Kubo, Yasufumi Ohkura, Hiroaki Kinoshita, Yasuhiro Mizoguchi, Shigefumi Takeda, Isao Yuasa, Shuzo Otani
Publikováno v:
The Japanese Journal of Gastroenterological Surgery. 25:1190-1190
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f4c89c07d09c0386d0687e231f9180c
https://doi.org/10.5833/jjgs.25.1190
https://doi.org/10.5833/jjgs.25.1190
Autor:
Fujiko Sanae, Ryousuke Sakai, Masaaki Nomura, Kazuhiko Sudo, Shigefumi Takeda, Yuichi Fujii, Ken-ichi Miyamoto, Shinya Wakusawa
Publikováno v:
Japanese Journal of Pharmacology. 55:304
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab967e4e2f66d860ad06fd7bf66e9fd1
https://doi.org/10.1016/s0021-5198(19)39299-6
https://doi.org/10.1016/s0021-5198(19)39299-6
Publikováno v:
Japanese Journal of Pharmacology. 52:336
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81234c450db9afdc629dc394a3030f29
https://doi.org/10.1016/s0021-5198(19)55832-2
https://doi.org/10.1016/s0021-5198(19)55832-2
Autor:
Shigefumi Takeda, Yukinobu Ikeya, Heihachiro Taguchi, Yoshio Kase, Hiroshi Mitsuhashi, Masaki Aburada
Publikováno v:
Phytochemistry. 27:569-573
A new dibenzocyclooctadiene lignan, isoschizandrin was isolated from the fruits of Schizandra chinensis . The structure was elucidated on the basis of the spectral analysis and chemical correlation with schizandrin and (+)− deoxyschizandrin. In exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ff19ae71ae9eb688b81039e9eb5987e
https://doi.org/10.1016/0031-9422(88)83143-1
https://doi.org/10.1016/0031-9422(88)83143-1
Autor:
Yoshio Kase, Yuko Sekiguchi, Shuji Funo, Seiji Morisawa, Masaki Aburada, Ichiro Arai, Yasuhiro Mizoguchi, Shigefumi Takeda, Masayuki Hasegawa, Eikichi Hosoya
Publikováno v:
Folia Pharmacologica Japonica. 88:321-330
正常ラットにおける肝部分切除による再生肝，肝組織血流量ならびに肝微細構造におよぼすTJN-101((+)-(6s，7s，R-biar)-5，6，7，8-tetrahydro-1，2，3，12-tetramethoxy-6，7-dimethyl-10，11-methylene-dioxy-6-di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e5773c47b4d66fb1578a40f77765896
https://doi.org/10.1254/fpj.88.321
https://doi.org/10.1254/fpj.88.321
Autor:
Masaki Aburada, Seiji Morisawa, Shigefumi Takeda, Yoshihide Sakagami, Sukeo Yamamoto, Yasufumi Ohkura, Kenzo Kobayashi, Yasuhiro Mizoguchi
Publikováno v:
Japanese Journal of Pharmacology. 44:179-185
TJN-101, which is a lignan component isolated from schisandra fruits, inhibits hepatotoxic chemicals-induced liver injuries. In this study, effects of TJN-101 on immunologically induced liver injuries were investigated in vivo and in vitro. When a sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a125a1276870428169f5c249c67a5f7
https://doi.org/10.1254/jjp.44.179
https://doi.org/10.1254/jjp.44.179