Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Shigeaki Umeda"'
Autor:
Haochen Zhang, Elias-Ramzey Karnoub, Shigeaki Umeda, Ronan Chaligné, Ignas Masilionis, Caitlin A. McIntyre, Palash Sashittal, Akimasa Hayashi, Amanda Zucker, Katelyn Mullen, Jungeui Hong, Alvin Makohon-Moore, Christine A. Iacobuzio-Donahue
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Implementing high-throughput single-cell DNA sequencing for the study of solid tumours has been challenging. Here, the authors present an optimised approach for snap-frozen tissue single nuclei extraction and DNA sequencing, which can be applied to s
Externí odkaz:
https://doaj.org/article/f547a2f202d1496d9bde6d8b1e24f513
Publikováno v:
Human Pathology: Case Reports, Vol 11, Iss , Pp 79-82 (2018)
Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare complication of cancer. It is histologically characterized by fibrocellular intimal proliferation in small pulmonary arteries and arterioles in patients with metastatic carcinoma. It is most
Externí odkaz:
https://doaj.org/article/e47b85c1d42448c58c69117b2efac005
Autor:
Mai Matsumura, Koji Okudela, Yu Nakashima, Hideaki Mitsui, Kaori Denda-Nagai, Takehisa Suzuki, Hiromasa Arai, Shigeaki Umeda, Yoko Tateishi, Chihiro Koike, Toshiaki Kataoka, Tatsuro Irimura, Kenichi Ohashi
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215237 (2019)
We investigated the significance of MUC21 in EGFR-mutated lung adenocarcinoma (LADC). Two-hundred forty-one surgically resected LADCs (116 EGFR-mutated and 125 wild-type tumors) were examined for immunohistochemical expression of MUC21 protein. A pol
Externí odkaz:
https://doaj.org/article/b1ee5c1e339b41efa882c8e8d36945c0
Autor:
Mai Matsumura, Koji Okudela, Yoko Kojima, Shigeaki Umeda, Yoko Tateishi, Akimasa Sekine, Hiromasa Arai, Tetsukan Woo, Michihiko Tajiri, Kenichi Ohashi
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166795 (2016)
The purpose of this study was to define histological features determining the malignant potential of EGFR-mutated lung adenocarcinoma (LADC). Surgically resected tumors (EGFR-mutated LADCs with (21) and without (79) lymph node metastasis and EGFR wil
Externí odkaz:
https://doaj.org/article/d90b6a52a48443e1a11236e8a5f2225f
Autor:
Koji Okudela, Akira Katayama, Tetsukan Woo, Hideaki Mitsui, Takehisa Suzuki, Yoko Tateishi, Shigeaki Umeda, Michihiko Tajiri, Munetaka Masuda, Noriyuki Nagahara, Hitoshi Kitamura, Kenichi Ohashi
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87193 (2014)
This study investigated the proteome modulated by oncogenic KRAS in immortalized airway epithelial cells. Chloride intracellular channel protein 4 (CLIC4), S100 proteins (S100A2 and S100A11), tropomyosin 2, cathepsin L1, integrinsα3, eukaryotic elon
Externí odkaz:
https://doaj.org/article/3b16af516d0147c9af5471edc7a90d2b
Autor:
Koji Okudela, Yoko Tateishi, Shigeaki Umeda, Hideaki Mitsui, Takeshisa Suzuki, Yuichi Saito, Tetsukan Woo, Michihiko Tajiri, Munetaka Masuda, Yohei Miyagi, Kenichi Ohashi
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100581 (2014)
Small non-protein coding RNA, microRNA (miR), which regulate messenger RNA levels, have recently been identified, and may play important roles in the pathogenesis of various diseases. The present study focused on miR-31 and investigated its potential
Externí odkaz:
https://doaj.org/article/86d386dd75e14aadb3b4d1d2ae37d48c
Autor:
Jing Hu, Francisco J. Sánchez-Rivera, Zhenghan Wang, Gabriela N. Johnson, Yu-jui Ho, Karuna Ganesh, Shigeaki Umeda, Siting Gan, Adriana M. Mujal, Rebecca B. Delconte, Jessica P. Hampton, Huiyong Zhao, Sanjay Kottapalli, Elisa de Stanchina, Christine A. Iacobuzio-Donahue, Dana Pe’er, Scott W. Lowe, Joseph C. Sun, Joan Massagué
Publikováno v:
Nature. 616:806-813
Autor:
Eileen M. O'Reilly, Christine Iacobuzio-Donahue, Marinela Capanu, Christopher Crane, David P. Kelsen, Kenneth H. Yu, Fiyinfolu Balogun, Fergus Keane, Anna M. Varghese, Marsha Reyngold, Shigeaki Umeda, Joanne F. Chou, Daniella Forman, Chaitanya Bandlamudi, Catherine A. O'Connor, Wungki Park
Supplementary Figure from Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d02dd03e584fdd44e38ae775d950cad
https://doi.org/10.1158/1078-0432.22488417
https://doi.org/10.1158/1078-0432.22488417
Autor:
Eileen M. O'Reilly, Christine Iacobuzio-Donahue, Marinela Capanu, Christopher Crane, David P. Kelsen, Kenneth H. Yu, Fiyinfolu Balogun, Fergus Keane, Anna M. Varghese, Marsha Reyngold, Shigeaki Umeda, Joanne F. Chou, Daniella Forman, Chaitanya Bandlamudi, Catherine A. O'Connor, Wungki Park
Supplementary Data from Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0550dabfb72da97336c9727af9f81a06
https://doi.org/10.1158/1078-0432.22488435.v1
https://doi.org/10.1158/1078-0432.22488435.v1
Autor:
Eileen M. O'Reilly, Christine Iacobuzio-Donahue, Marinela Capanu, Christopher Crane, David P. Kelsen, Kenneth H. Yu, Fiyinfolu Balogun, Fergus Keane, Anna M. Varghese, Marsha Reyngold, Shigeaki Umeda, Joanne F. Chou, Daniella Forman, Chaitanya Bandlamudi, Catherine A. O'Connor, Wungki Park
Purpose:Characterizing germline and somatic ATM variants (gATMm, sATMm) zygosity and their contribution to homologous recombination deficiency (HRD) is important for therapeutic strategy in pancreatic ductal adenocarcinoma (PDAC).Experimental Design:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af45f3d05c721b60d9d261257f758660
https://doi.org/10.1158/1078-0432.c.6532713
https://doi.org/10.1158/1078-0432.c.6532713