Removal of p16 ^INK4 Expressing Cells in Late Life has Moderate Beneficial Effects on Skeletal Muscle Function in Male Mice.

Autor: Guzman SD; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States., Judge J; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States., Shigdar SM; Department of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool and MRC-Arthritis Research UK Centre for Integrated Research Into Musculoskeletal Ageing (CIMA), Liverpool, United Kingdom., Paul TA; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States., Davis CS; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States., Macpherson PC; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States., Markworth JF; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States., Van Remmen H; Aging and Metabolism Research Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, United States.; Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.; Oklahoma City VA Medical Center, Oklahoma City, OK, United States., Richardson A; Oklahoma City VA Medical Center, Oklahoma City, OK, United States.; Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States., McArdle A; Department of Musculoskeletal Biology, Institute of Ageing and Chronic Disease, University of Liverpool and MRC-Arthritis Research UK Centre for Integrated Research Into Musculoskeletal Ageing (CIMA), Liverpool, United Kingdom., Brooks SV; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, United States.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States.

Publikováno v: Frontiers in aging [Front Aging] 2022 Jan 26; Vol. 2, pp. 821904. Date of Electronic Publication: 2022 Jan 26 (Print Publication: 2021).