Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Shifang Luo"'
Autor:
Feifan Liu, Yuanmei Bai, Yan Wan, Shifang Luo, Linao Zhang, Xue Wu, Rong Chen, Zili Yin, Yuhuan Xie, Peixin Guo
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Gouty nephropathy (GN) arises from factors like excessive purine intake, metabolic disorders or abnormal synthesis, and uric acid hypersaturation in the blood, leading to urate crystal deposition in kidney tissue. DaiTongXiao (DTX) is a
Externí odkaz:
https://doaj.org/article/c7d54e6d4b0743f38ba6556c882d3760
Autor:
Qinghua Zeng, Zhimin Long, Min Feng, Yueyang Zhao, Shifang Luo, Kejian Wang, Yingxiong Wang, Guang Yang, Guiqiong He
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Alzheimer’s disease (AD) is an age-related neurodegenerative disease characterized by the deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles (NFTs) and massive loss of neuronal cells in the brain. Adult hippocampus continuously gen
Externí odkaz:
https://doaj.org/article/62348a0b58b1456f8bc92a159c53cb27
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 10, Pp 2078-2085 (2021)
Neural Regeneration Research
Neural Regeneration Research
Postmenopausal women with Alzheimer's disease (AD) exhibit dramatically reduced sensitivity to estrogen replacement therapy, which is though to be related to an estrogen receptor (ER)α/ERβ ratio imbalance arising from a significantly decreased leve
Publikováno v:
Acta Metallurgica Sinica (English Letters). 34:597-605
Generally, the good combination of pre-deformation and aging can improve the mechanical strength of the Al–Cu–Li–Mg alloys. However, the effects of pre-deformation on competitive precipitation relationship and precipitation strengthening have n
Publikováno v:
International Journal of Molecular Medicine.
The abnormal activation of glycogen synthase kinase 3β (GSK3β) is one of the mechanisms involved in the pathogenesis of Alzheimer's disease (AD), which results in amyloid β‑peptide (Aβ) plaque overproduction, Tau hyperphosphorylation and neuron
Autor:
Qinghua, Zeng, Zhimin, Long, Min, Feng, Yueyang, Zhao, Shifang, Luo, Kejian, Wang, Yingxiong, Wang, Guang, Yang, Guiqiong, He
Publikováno v:
Frontiers in Aging Neuroscience
Alzheimer’s disease (AD) is an age-related neurodegenerative disease characterized by the deposition of amyloid-β (Aβ) peptides and neurofibrillary tangles (NFTs) and massive loss of neuronal cells in the brain. Adult hippocampus continuously gen
Autor:
Zhimin Long, Xiao-Feng Li, Guiqiong He, Lei Zhao, Kejian Wang, Min Zheng, Rong Jiang, Shifang Luo
Publikováno v:
CNS Neuroscience & Therapeutics. 21:887-897
Summary Aim Tau hyperphosphorylation and amyloid β-peptide overproduction, caused by altered localization or abnormal activation of glycogen synthase kinase-3β (GSK-3β), is a pathogenic mechanism in Alzheimer's disease (AD). Valproic acid (VPA) at
Publikováno v:
Acta Biochimica et Biophysica Sinica
Epidemiologic studies have demonstrated that women account for two-thirds of Alzheimer’s disease (AD) cases, for which the decline in circulating gonadal hormone is considered to be one of the major risk factors. In addition, ovarian hormone defici
Publikováno v:
Experimental neurology. 283
Alzheimer's disease (AD) is the most common type of dementia frequently responsible for cognitive decline in the elderly. The etiology and molecular mechanism of AD pathogenesis remain inconclusive. Aging and vascular factors are important independen
Distribution and expression of Pen-2 in the central nervous system of APP/PS1 double transgenic mice
Publikováno v:
Acta biochimica et biophysica Sinica. 47(4)
The γ-secretase complex catalyzes the final cleavage step of amyloid β-protein precursor (APP) to generate amyloid β (Aβ) peptide, a pathogenic component of senile plaques in the brain of Alzheimer's disease (AD) patients. Recent studies have sho