High Quality Draft Genome of Arogyapacha (Trichopus zeylanicus), an Important Medicinal Plant Endemic to Western Ghats of India

Autor: Biju Vadakkemukadiyil Chellappan, Shidhi PR, Sheethal Vijayan, Veena S. Rajan, Anu Sasi, Achuthsankar S. Nair

Publikováno v: G3: Genes, Genomes, Genetics, Vol 9, Iss 8, Pp 2395-2404 (2019)

Arogyapacha, the local name of Trichopus zeylanicus, is a rare, indigenous medicinal plant of India. This plant is famous for its traditional use as an instant energy stimulant. So far, no genomic resource is available for this important plant and he

Externí odkaz: https://doaj.org/article/16d994f92e314cf5b3393574d0931fbf

Bioinformatics Probing of Tissue-Specific MiRNAs Overexpressed in Active Tuberculosis Reveals Induction of Multiple Cancer Pathways

Autor: Shidhi Pr, Jules-Roger Kuiate, Ousman Tamgue, Ambily Nath, Elvis Ndukong Ndzi, Chellappan V Biju, Alexis Ndjolo, Celine Nguefeu Nkenfou, Achuthsankar S. Nair

Publikováno v: Journal of Applied Bioinformatics & Computational Biology.

This study attempts to discern the genes and pathways of tissue-specific miRNAs overexpressed in active tuberculosis (TB). The chosen 11 miRNAs were grouped into serum (S1), sputum (S2), and peripheral blood mononuclear cell (PBMC) (S3) classes. DIAN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14e934de75e5e29dfe7f1dfd9079b2ab
https://doi.org/10.4172/2329-9533.1000153

Making novel proteins from pseudogenes

Autor: Shidhi Pr, Pawan K. Dhar, Shailja Singh, Prashanth Suravajhala, Aysha Nayeema, Achuthsankar S. Nair

Publikováno v: Bioinformatics (Oxford, England). 31(1)

Motivation: Recently, we made synthetic proteins from non-coding DNA of Escherichia coli . Encouraged by this, we asked: can we artificially express pseudogenes into novel and functional proteins? What kind of structures would be generated? Would the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2691943c42bbd57478254915e0a5bb00
https://pubmed.ncbi.nlm.nih.gov/25236460

Complete chloroplast genome of the medicinal plant Evolvulus alsinoides : comparative analysis, identification of mutational hotspots and evolutionary dynamics with species of Solanales.

Autor: Shidhi PR; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India., Nadiya F; Department of Biotechnology, Inter University Centre for Genomics and Gene Technology, University of Kerala, Thiruvananthapuram, Kerala India., Biju VC; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India., Vijayan S; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India., Sasi A; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India., Vipin CL; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India., Janardhanan A; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India., Aswathy S; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India., Rajan VS; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India., Nair AS; Department of Computational Biology and Bioinformatics, University of Kerala, Thiruvananthapuram, Kerala India.

Publikováno v: Physiology and molecular biology of plants : an international journal of functional plant biology [Physiol Mol Biol Plants] 2021 Aug; Vol. 27 (8), pp. 1867-1884. Date of Electronic Publication: 2021 Aug 25.

Making novel proteins from pseudogenes.

Autor: Shidhi PR; Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India., Suravajhala P; Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India., Nayeema A; Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India., Nair AS; Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India., Singh S; Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India., Dhar PK; Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India Department of Computational Biology and Bioinformatics, University of Kerala, Kariyavattom, Trivandrum- 695 581, India, Bioinformatics.Org, 28 Pope Street, Hudson, MA 01749, USA, Bioclues.org, India, Bioclues.org, Denmark, National College, University of Kerala, Trivandrum- 695 009, Department of Life Sciences, School of Natural Sciences, Shiv Nadar University, Dadri, Uttar Pradesh- 201 314, and Centre for Systems and Synthetic Biology, University of Kerala, Kariyavattom, Trivandrum- 695 581, India.

Publikováno v: Bioinformatics (Oxford, England) [Bioinformatics] 2015 Jan 01; Vol. 31 (1), pp. 33-9. Date of Electronic Publication: 2014 Sep 17.