Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shideh Montasser Kouhsari"'
Publikováno v:
Cell Journal, Vol 25, Iss 10, Pp 717-726 (2023)
Objective: Vaccinium arctostaphylos has traditionally been employed in Iranian folk medicine to treat diabetes.However, the precise molecular mechanisms underlying its antidiabetic properties remain incompletely understood.The current experiment inte
Externí odkaz:
https://doaj.org/article/fd3cd18454bf41e99b783bf0d50a3c74
Autor:
Nasser Pouladi, Mohammad-Ali HosseinpourFeizi, Shideh Montasser Kouhsari, Davoud Farajzadeh, Hourieh Khani, Reyhaneh Ravanbakhsh Gavgani, Narges Dastmalch, Yalda Arghavanian
Publikováno v:
Journal of Kerman University of Medical Sciences, Vol 25, Iss 3, Pp 228-242 (2018)
Background: This study was done in order to enhance our understanding about molecular and epidemiological features of breast cancer among the Azeri population with special emphasis on the detection of TP53 mutations. We also analyzed the role of the
Externí odkaz:
https://doaj.org/article/21de43a0105c416f8bac0b5241a80689
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 7, Iss 4, Pp 547-556 (2017)
MicroRNAs (miRNAs) are endogenous non-coding RNAs that have significant roles in biological processes such as glucose homoeostasis. MiRNAs fine-tune target genes expression via sequence-specific binding of their seed sequence to the untranslated regi
Externí odkaz:
https://doaj.org/article/396a4f13d11849bfb8919132f2c466fd
Publikováno v:
Cell Journal, Vol 19, Iss 4, Pp 520-527 (2017)
Objective: Reactive oxygen species (ROS) is an apoptosis inducer in pancreatic β-cells that stimulates p53/p65 mediated microRNA (miR)-145 expression. Punica granatum L. (pomegranate) is an antioxidant fruit that attenuates ROS generation. This st
Externí odkaz:
https://doaj.org/article/6c0d45878ee9467fb8abbe0c016e9c53
Phytochemicals, withaferin A and carnosol, overcome pancreatic cancer stem cells as c-Met inhibitors
Autor:
Shideh Montasser Kouhsari, Seyed Nasser Ostad, Amir Shadboorestan, Seyed Shahriar Arab, Shima Aliebrahimi
Publikováno v:
Biomedicine & Pharmacotherapy. 106:1527-1536
Receptor tyrosine kinases (RTKs) are pharmaceutically attractive targets due to their fundamental role in tumor formation. The hallmark of pancreatic cancer is its high mortality rate attributed to the existence of cancer stem cell (CSC) subpopulatio
Autor:
Seyed Shahriar Arab, Leila Karami, Shima Aliebrahimi, Shideh Montasser Kouhsari, Seyed Nasser Ostad
Publikováno v:
Cell Biochemistry and Biophysics
c-Met receptor tyrosine kinase is a proto-oncogene whose aberrant activation is attributed to a lower rate of survival in most cancers. Natural product-derived inhibitors known as "fourth generation inhibitors" constitute more than 60% of anticancer
Publikováno v:
Iranian Journal of Pharmaceutical Research : IJPR
Pancreatic β-cells dysfunction and impairment of insulin action usually leads to hyperglycemia. Punica granatum L. is a well-known traditional herbal remedy in Iran due to its positive effects on ameliorating blood glucose homeostasis. In this study
Publikováno v:
Molecular Neurobiology. 54:5657-5667
Loss of motor and sensory function as a result of neuronal cell death and axonal degeneration are the hallmarks of spinal cord injury. To overcome the hurdles and achieve improved functional recovery multiple aspects, it must be taken into account. T
Publikováno v:
Molecular Neurobiology. 54:1119-1128
Parkinson's disease (PD) is a progressive neurological disorder characterized by a large number of motor and non-motor features and is known as the second most common neurodegenerative disorder after Alzheimer's disease. The hallmark pathology of PD
Publikováno v:
Experimental and clinical endocrinologydiabetes : official journal, German Society of Endocrinology [and] German Diabetes Association. 127(9)
Diabetes mellitus is a complex metabolic disease around the world that is characterized by hyperglycemia resulting from impaired insulin secretion, insulin action, or both. MicroRNA-29a is an important regulator of insulin signaling and gluconeogenes