Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shichuan Tan"'
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Gliomas, a type of primary brain tumor, have emerged as a threat to global mortality due to their high heterogeneity and mortality. A low-grade glioma (LGG), although less aggressive compared with glioblastoma, still exhibits high recurrence and mali
Externí odkaz:
https://doaj.org/article/979dfad3819b4cb997c3867bec13aa0b
Purpose Polo-like kinases are a family of serine-threonine kinases that exert regulatory effects on diverse cellular processes. Dysregulation of PLKs has been implicated in multiple cancers, including glioblastoma (GBM). Notably, PLK2 expression in G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b258a7023634f2556da38d73b06c8c3
https://doi.org/10.21203/rs.3.rs-2687542/v1
https://doi.org/10.21203/rs.3.rs-2687542/v1
Publikováno v:
CNS neurosciencetherapeutics. 28(11)
To explore the expression changes and roles of the RNA-binding protein RCAN1.1 in acute ischemic stroke (AIS), and to preliminarily confirm the medicinal value of the RNA aptamer R1SR13 in AIS by targeting RCAN1.1.Two mouse AIS models of middle cereb
Autor:
Huan Yang, Ming Wu, Yongyi Zeng, Geng Chen, Zhixiong Cai, Xiaolong Liu, Da Zhang, Xiuqing Dong, Shichuan Tang, Ruijing Tang, Kongying Lin, Jun Fu, Yutong Guo, Fangzhou Lin, Tingfeng Huang, Jie Kong, Xiaowei Yin, Aimin Ge, Qizhu Lin
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 12 (2024)
Background Liver metastasis is highly aggressive and immune tolerant, and lacks effective treatment strategies. This study aimed to develop a neoantigen hydrogel vaccine (NPT-gels) with high clinical feasibility and further investigate its efficacy a
Externí odkaz:
https://doaj.org/article/4b5e6d75ca97495a8b21d18178d70808
Publikováno v:
Journal of Neurochemistry. 157:467-478
Aberrant expression and phosphorylation of insulin receptor substrate 1 (IRS-1) contribute to brain insulin resistance. However, the underlying mechanism remains elusive. The insulin signaling and Wnt/β-catenin signaling are two critical pathways fo
Autor:
Liyan Huang, Chen Zhang, Pin Wang, Yun Zhang, Yan Yun, Weihong Song, Xiulian Sun, Shichuan Tan, Carles Vilariño-Güell
Publikováno v:
Molecular psychiatry. 26(4)
Posttranscriptional regulation of gene expression plays an important role in the maturation, transport, stability and translation of coding and noncoding RNAs. RNA-binding protein (RBP) is a key factor of the regulation. Regulator of calcineurin 1 (R
Autor:
Tenglong Yan, Minghui Wang, Siwen Yang, Yuqian Wang, Xingfan Zhou, Xiaojun Zhu, Wenjun Ma, Shichuan Tang, Jue Li
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
Evidence suggests that agricultural workers are at higher risk of insulin resistance (IR), but few studies have investigated IR in solar greenhouse workers, who are exposed to higher concentrations of agricultural risk factors than traditional agricu
Externí odkaz:
https://doaj.org/article/f829d57a1b69447582dab21cf8913c4f
Autor:
Ranran Wang, Yongguang Tao, Fenglei Yu, Yunping Li, Jingqun Tang, Chen Chen, Xiang Wang, Shichuan Tan
Publikováno v:
Experimental and therapeutic medicine. 11(3)
Pulmonary tuberculosis (TB) is a major global health problem. Endothelin (ET)-1 is an important pro-inflammatory factor in the airways, which acts as a chemoattractant and an upregulator of other inflammatory mediators. In the present study, the asso
Autor:
XIANG WANG, JINGQUN TANG, RANRAN WANG, CHEN CHEN, SHICHUAN TAN, FENGLEI YU, YONGGUANG TAO, YUNPING LI
Publikováno v:
Experimental & Therapeutic Medicine; Mar2016, Vol. 11 Issue 3, p1104-1108, 5p
Publikováno v:
Environmental Health, Vol 18, Iss 1, Pp 1-10 (2019)
Abstract Background Uncertainty remains regarding the association between blood lead levels (BLL) and serum uric acid (SUA) with relatively low BLL exposure because of limited data in the adolescent population. We examined the association between BLL
Externí odkaz:
https://doaj.org/article/801df0d62416415c976f0d7ad7b30268