Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shichuan Hu"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 12 (2024)
Background Although immunotherapy can reinvigorate immune cells to clear tumors, the response rates are poor in some patients. Here, CD47 antibody-engineered oncolytic viruses (oAd-αCD47) were employed to lyse tumors and activate immunity. The oAd-
Externí odkaz:
https://doaj.org/article/ea041a1eee9c4639beaddf5c8911df12
Autor:
Zhongbing Qi, Jing Zhao, Yuhua Li, Bin Zhang, Shichuan Hu, Yanwei Chen, Jinhu Ma, Yongheng Shu, Yunmeng Wang, Ping Cheng
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Glioblastomas (GBMs) are highly aggressive brain tumors that have developed resistance to currently available conventional therapies, including surgery, radiation, and systemic chemotherapy. In this study, we investigated the safety of a live attenua
Externí odkaz:
https://doaj.org/article/04a1820a19f54e64a515a2c1006c5084
Autor:
Liuliu Cheng, Shichuan Hu, Jinhu Ma, Yongheng Shu, Yanwei Chen, Bin Zhang, Zhongbing Qi, Yunmeng Wang, Yan Zhang, Yuwei Zhang, Ping Cheng
Publikováno v:
Molecular Biomedicine, Vol 3, Iss 1, Pp 1-16 (2022)
Abstract Accumulating evidence indicates that hepatitis B virus X protein (HBx) plays a key role in HBV-related hepatocellular carcinoma (HCC) aggressiveness; however, the underlying mechanisms are not entirely clear. Long non-coding RNAs (lncRNAs),
Externí odkaz:
https://doaj.org/article/e2dab277fd43498c8a9327273a1fa218
Autor:
Bin Zhang, Yongheng Shu, Shichuan Hu, Zhongbing Qi, Yanwei Chen, Jinhu Ma, Yunmeng Wang, Ping Cheng
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In situ tumor vaccine is a potential cancer therapy due to their advantages in induction of antitumor immune responses. Oncolytic virotherapy utilizes natural or engineered oncolytic viruses to kill tumors selectively, representing a promising in sit
Externí odkaz:
https://doaj.org/article/7a36eb68979741d38c66a4901df73d29
Autor:
Jinhu Ma, Chao Su, Shichuan Hu, Yanwei Chen, Yongheng Shu, Dan Yue, Bin Zhang, Zhongbing Qi, Suli Li, Xilei Wang, Yueting Kuang, Ping Cheng
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 35-46 (2020)
To ensure the high purity and biological activity of the adenovirus vector to be used for clinical applications, a stable and linearly scalable preparation method is highly imperative. During the adenovirus-harvesting process, the Triton X-100-based
Externí odkaz:
https://doaj.org/article/8a14a48a25134119b247fc8ecde756d5
Autor:
Ping Cheng, Yongheng Shu, Yueting Kuang, Yanwei Chen, Zhongbing Qi, Bin Zhang, Jinhu Ma, Shichuan Hu
Publikováno v:
Human Gene Therapy. 33:237-249
Solid tumors are characterized by abundant extracellular matrix originating from cancer-associated fibroblasts (CAFs). High collagen content can trigger the collapse of vascular system in the tumor and form physical barrier that eventually impedes th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::315ebdb41d310850cf582e2c59918494
https://doi.org/10.1089/hum.2021.048
https://doi.org/10.1089/hum.2021.048
Autor:
Shichuan Hu, Zhang Yong, Bin Zhang, Dan Yue, Chunxue Zhang, Chao Su, Jinhu Ma, Yan Zhang, Zhongbing Qi, Ping Cheng, Yanwei Chen, Anliang Huang, Gang Shi, Yongheng Shu, Hongxin Deng
Publikováno v:
Mol Ther
Preclinical and clinical studies have validated the antitumor effects of several oncolytic viruses (OVs). However, the efficacy of OVs is limited when they are administered as monotherapies. Combination therapy is a promising direction for oncolytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafc54f5969baa45066d0293edf9ec90
https://doi.org/10.1016/j.ymthe.2021.09.015
https://doi.org/10.1016/j.ymthe.2021.09.015
Autor:
Gang Shi, Ping Cheng, Yongheng Shu, Anliang Huang, Yueting Kuang, Jinhu Ma, Chao Su, Yuwei Zhang, Bin Zhang, Shichuan Hu, Yan Zhang, Zhongbing Qi, Yanwei Chen
Publikováno v:
Acta Biomaterialia. 135:567-581
Tumor vaccines that induce effective and sustained antitumor immunity are highly promising for cancer therapy. However, the antitumor potential of these vaccines is weakened due to the immunosuppressive characteristics of the tumor microenvironment (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dd28b6ef208603fc5954ddf24362503
https://doi.org/10.1016/j.actbio.2021.09.003
https://doi.org/10.1016/j.actbio.2021.09.003
Autor:
Bin Zhang, Yueting Kuang, Yongheng Shu, Ping Cheng, Suli Li, Dan Yue, Zhongbing Qi, Yanwei Chen, Shichuan Hu, Xilei Wang, Jinhu Ma, Chao Su
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 35-46 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss, Pp 35-46 (2020)
To ensure the high purity and biological activity of the adenovirus vector to be used for clinical applications, a stable and linearly scalable preparation method is highly imperative. During the adenovirus-harvesting process, the Triton X-100-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49a919163a0640f8610f8246865a9dcb
https://doi.org/10.1016/j.omtm.2020.08.013
https://doi.org/10.1016/j.omtm.2020.08.013
Autor:
Liuliu Cheng, Shichuan Hu, Jinhu Ma, Yongheng Shu, Yanwei Chen, Bin Zhang, Zhongbing Qi, Yunmeng Wang, Yan Zhang, Yuwei Zhang, Ping Cheng
Publikováno v:
Molecular Biomedicine, Vol 3, Iss 1, Pp 1-16 (2022)
Accumulating evidence indicates that hepatitis B virus X protein (HBx) plays a key role in HBV-related hepatocellular carcinoma (HCC) aggressiveness; however, the underlying mechanisms are not entirely clear. Long non-coding RNAs (lncRNAs), which par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bebe52b05451b47acfbf23290f7b1346
https://pubmed.ncbi.nlm.nih.gov/35122182
https://pubmed.ncbi.nlm.nih.gov/35122182