Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Shichen Hu"'
Autor:
Weiwei Wang, Jun Shi, Yan Zhang, Yuanzheng Qiao, Wenbo Zuo, Zhiyuan Wang, Tingbin Nong, Shichen Hu, Yang Chen, Ruiyang Kong, Xiumiao He, Ping Wei
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Infectious bursal disease (IBD) classical virus strain (cIBDV) can cause morbidity and mortality in young chickens with severe long-term immunosuppression. However, since the emergence and widespread prevalence of very virulent strain (vvIBDV) in Chi
Externí odkaz:
https://doaj.org/article/1b5304b81f89427a99dfe918c5d5e1ed
Publikováno v:
Energies, Vol 16, Iss 20, p 7158 (2023)
The highlighted energy consumption of Internet data center (IDC) in China has become a pressing issue with the implementation of the Chinese dual carbon strategic goal. This paper provides a comprehensive review of cooling technologies for IDC, inclu
Externí odkaz:
https://doaj.org/article/2c24b1fa44f44ee6ad749007ca2ca703
Autor:
Huyan Meng, Guowei Wu, Xinsuo Zhao, Anhui Wang, Dekang Li, Yilun Tong, Taijie Jin, Ye Cao, Bing Shan, Shichen Hu, Ying Li, Lifeng Pan, Xiaoxu Tian, Ping Wu, Chao Peng, Junying Yuan, Guohui Li, Li Tan, Zhaoyin Wang
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-18 (2021)
Abstract RIPK1, a death domain-containing kinase, has been recognized as an important therapeutic target for inhibiting apoptosis, necroptosis, and inflammation under pathological conditions. RIPK1 kinase inhibitors have been advanced into clinical s
Externí odkaz:
https://doaj.org/article/933cebcdfc1c4ca5a3e8adfa7b6a2bbb
Autor:
Shichen Hu, Yujiao Guo, Yingli Wang, Ying Li, Tao Fu, Zixuan Zhou, Yaru Wang, Jianping Liu, Lifeng Pan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Myosin VI can facilitate the maturation of autophagosomes in autophagy through interactions with Tom1 and autophagy receptors. Here authors report the structure of the cargobinding domain of Myosin VI in complex with Tom1, which provides insights int
Externí odkaz:
https://doaj.org/article/945bfe09b3fb4db79823e2b763ce2484
Structural Insights into SHARPIN-Mediated Activation of HOIP for the Linear Ubiquitin Chain Assembly
Publikováno v:
Cell Reports, Vol 21, Iss 1, Pp 27-36 (2017)
The linear ubiquitin chain assembly complex (LUBAC) is the sole identified E3 ligase complex that catalyzes the formation of linear ubiquitin chain, and it is composed of HOIP, HOIL-1L, and SHARPIN. The E3 activity of HOIP can be effectively activate
Externí odkaz:
https://doaj.org/article/8068bbaa82e6433b8c7d3e2e779f354b
Autor:
Faxiang Li, Xingqiao Xie, Yingli Wang, Jianping Liu, Xiaofang Cheng, Yujiao Guo, Yukang Gong, Shichen Hu, Lifeng Pan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Mutations in optineurin that cause defects in the interaction with TBK1 are associated with neurodegenerative diseases. Here, the authors report the structure of this complex, and outline a general binding mode for these proteins.
Externí odkaz:
https://doaj.org/article/6f149eadfad341e89e90455b3ba5ac86
Autor:
Shichen Hu
Publikováno v:
Proceedings of the 2022 3rd International Conference on Artificial Intelligence and Education (IC-ICAIE 2022) ISBN: 9789464630398
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdc5825db6a9d9b6faad0a8b86f01faf
https://doi.org/10.2991/978-94-6463-040-4_217
https://doi.org/10.2991/978-94-6463-040-4_217
Autor:
Jingwu Kang, Lifeng Pan, Shichen Hu, Ying Han, Tao Fu, Guizhen Liu, Xuepei Zhang, Piliang Hao, Mengmeng Zheng
Publikováno v:
Analytical Chemistry. 92:3913-3922
We describe an affinity purification-mass spectrometry (AP-MS) method for probing the interactome of a special targeting protein. The AP was implemented with monolithic micro immobilized metal ion affinity chromatography columns (m-IMAC) which were p
Autor:
Zhe Chen, Qian Guo, Shichen Huang, Lei Li, Feng Wu, Zhilong Liu, Zhigang Li, Tao Chen, Guanbin Song, Shuangnian Xu, Jieping Chen, Yu Hou
Publikováno v:
Genes and Diseases, Vol 11, Iss 1, Pp 397-412 (2024)
Therapeutic targeting FOXO3A (a forkhead transcription factor) represents a promising strategy to suppress acute myeloid leukemia (AML). However, the effective inhibitors that target FOXO3A are lacking and the adaptive response signaling weakens the
Externí odkaz:
https://doaj.org/article/b33e1bcc6d044eb48a488a7c6821576b
Autor:
Ying Li, Taijie Jin, Ye Cao, Li Tan, Zhaoyin Wang, Ping Wu, Yilun Tong, Huyan Meng, Xiaoxu Tian, Chao Peng, Xinsuo Zhao, Lifeng Pan, Bing Shan, Guowei Wu, Anhui Wang, Junying Yuan, Guohui Li, Shichen Hu, Dekang Li
Publikováno v:
Cell Discovery
Cell Discovery, Vol 7, Iss 1, Pp 1-18 (2021)
Cell Discovery, Vol 7, Iss 1, Pp 1-18 (2021)
RIPK1, a death domain-containing kinase, has been recognized as an important therapeutic target for inhibiting apoptosis, necroptosis, and inflammation under pathological conditions. RIPK1 kinase inhibitors have been advanced into clinical studies fo