Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Shichao Huang"'
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-4 (2024)
Abstract Accumulating evidence has shown that some hallucinogens, such as LSD, have fast and persistent effects on anxiety and depression. According to a proposed mechanism, LSD activates the TrkB and HTR2A signaling pathways, which enhance the densi
Externí odkaz:
https://doaj.org/article/347d674b1373475781278fdbb5d542c1
Publikováno v:
Biomolecules, Vol 14, Iss 2, p 189 (2024)
As a lifelong source of neurons, neural stem cells (NSCs) serve multiple crucial functions in the brain. The senescence of NSCs may be associated with the onset and progression of Alzheimer’s disease (AD). Our study reveals a noteworthy finding, in
Externí odkaz:
https://doaj.org/article/715b58d4bbaf451a8c85598e38e62e69
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-10 (2022)
Abstract The apolipoprotein E4 (APOE4) genotype is one of the strongest genetic risk factors for Alzheimer’s disease (AD), and is generally believed to cause widespread pathological alterations in various types of brain cells. Here, we developed a
Externí odkaz:
https://doaj.org/article/d9bf86bbf4e646fbb161d92d5ed36b88
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Cellular senescence is a major biological process related to aging. Neuronal cell senescence contributes to the pathogenesis of many aging-related neurodegenerative diseases including Alzheimer’s disease (AD). In this study, we showed that amyloid-
Externí odkaz:
https://doaj.org/article/38c4539b7ac84d2d9c3546a89ffe60e7
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3398 (2023)
Dysfunctional mitochondria and mitophagy are hallmarks of Alzheimer’s disease (AD). It is widely accepted that restoration of mitophagy helps to maintain cellular homeostasis and ameliorates the pathogenesis of AD. It is imperative to create approp
Externí odkaz:
https://doaj.org/article/032e2d51f4a64ea9a8cb1870afee9a66
Autor:
Zijuan Chen, Ruixue Zhou, Yihua Zhang, Doudou Hao, Yu Wang, Shichao Huang, Ningning Liu, Chunmei Xia, Nissan Yissachar, Feng Huang, Yiwei Chu, Dapeng Yan
Publikováno v:
Gut Microbes, Vol 11, Iss 5, Pp 1423-1437 (2020)
The protein translocated intimin receptor (Tir) from enteropathogenic Escherichia coli shares sequence similarity with the host cellular immunoreceptor tyrosine-based inhibition motifs (ITIMs). The ITIMs of Tir are required for Tir-mediated immune in
Externí odkaz:
https://doaj.org/article/9073654e28084466bfce6a609f99abbc
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9118 (2022)
Structural and functional alterations of vasculature caused by age-related factors is critically involved in the pathogenesis of ischemic stroke. The longevity genes sirtuins (SIRTs) are extensively investigated in aging-associated pathologies, but t
Externí odkaz:
https://doaj.org/article/09c20bd75b8c4fe9965bf9c9dcc29a01
Publikováno v:
Energies, Vol 15, Iss 10, p 3659 (2022)
Aiming at the problem that power load data are stochastic and that it is difficult to obtain accurate forecasting results by a single algorithm, in this paper, a combined forecasting method for short-term power load was proposed based on the Complete
Externí odkaz:
https://doaj.org/article/415e4d08c54a460e9ae8aac7d1a9a79e
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Neuroinflammation induced by overactivated glia cells is believed to be a major hallmark of Alzheimer's disease (AD) and a hopeful target against AD. A rhamnoside PL201 was previously reported to promote neurogenesis and ameliorate AD, and in this st
Externí odkaz:
https://doaj.org/article/cf14383ebb234478bc1ea395e2d3fb96
Publikováno v:
Stem Cell Reports, Vol 8, Iss 5, Pp 1124-1134 (2017)
The recent establishment of mammalian haploid embryonic stem cells (ESCs) provides new possibilities for genetic screening and for understanding genome evolution and function. However, the dynamics of mitosis in haploid ESCs is still unclear. Here, w
Externí odkaz:
https://doaj.org/article/7e9202fe3b264851ace70ff8940ace3d