Macropinoscope: Real-Time Simultaneous Tracking of pH and Cathepsin B Activity in Individual Macropinosomes.

Autor: Hirose H; Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan., Nakata E; Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011, Japan., Zhang Z; Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011, Japan., Shibano Y; Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011, Japan., Maekawa M; Division of Physiological Chemistry and Metabolism, Graduate School of Pharmaceutical Sciences, Keio University, Minato, Tokyo 105-8512, Japan., Morii T; Institute of Advanced Energy, Kyoto University, Uji, Kyoto 611-0011, Japan., Futaki S; Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan.

Publikováno v: Analytical chemistry [Anal Chem] 2023 Aug 01; Vol. 95 (30), pp. 11410-11419. Date of Electronic Publication: 2023 Jul 19.

Preparation and Evaluation of Hydrogel Film Containing Tramadol for Reduction of Peripheral Neuropathic Pain.

Autor: Natori N; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, 278-8510 Chiba, Japan., Shibano Y; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, 278-8510 Chiba, Japan., Hiroki A; National Institutes for Quantum Science and Technology, 1233 Watanuki, Takasaki-shi, 370-1292 Gunma, Japan., Taguchi M; National Institutes for Quantum Science and Technology, 1233 Watanuki, Takasaki-shi, 370-1292 Gunma, Japan., Miyajima A; Faculty of Pharmaceutical Sciences, Meiji Pharmaceutical University, 2-522-1 Noshio, Kiyose-shi, 204-8588 Tokyo, Japan., Yoshizawa K; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, 278-8510 Chiba, Japan., Kawano Y; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, 278-8510 Chiba, Japan. Electronic address: y.kawano@rs.tus.ac.jp., Hanawa T; Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda-shi, 278-8510 Chiba, Japan. Electronic address: t-hanawa@rs.tus.ac.jp.

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2023 Jan; Vol. 112 (1), pp. 132-137. Date of Electronic Publication: 2022 May 20.

A Collaborative Study on the Classification of Silicone Oil Droplets and Protein Particles Using Flow Imaging Method.

Autor: Shibata H; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan. Electronic address: h-shibata@nihs.go.jp., Terabe M; Pharmaceutical Technology Division, Analytical Development Department, Chugai Pharmaceutical Co. Ltd., 5-1 Ukima, 5-chome, Kita-ku, Tokyo 115-8543 Japan., Shibano Y; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan., Saitoh S; Pharmaceutical Technology Division, Analytical Development Department, Chugai Pharmaceutical Co. Ltd., 5-1 Ukima, 5-chome, Kita-ku, Tokyo 115-8543 Japan., Takasugi T; Analytical Research Laboratories, Pharmaceutical Technology, Astellas Pharma. Inc., 5-2-3 Tokodai, Tsukuba, Ibaraki, 300-2698, Japan., Hayashi Y; Analytical Research Laboratories, Pharmaceutical Technology, Astellas Pharma. Inc., 5-2-3 Tokodai, Tsukuba, Ibaraki, 300-2698, Japan., Okabe S; Research Division, CMC Development Research, Formulation Research Unit, Formulation Development, JCR Pharmaceuticals Co., Ltd., 2-2-9 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan., Yamaguchi Y; Research Division, CMC Development Research, Formulation Research Unit, Formulation Development, JCR Pharmaceuticals Co., Ltd., 2-2-9 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan., Yasukawa H; Research Division, CMC Development Research, Formulation Research Unit, Formulation Development, JCR Pharmaceuticals Co., Ltd., 2-2-9 Murotani, Nishi-ku, Kobe, Hyogo 651-2241, Japan., Suetomo H; Bio Process Research and Development Laboratories, Production Division, Kyowa Kirin Co., Ltd., 100-1, Hagiwara-machi, Takasaki, Gunma 370-0013, Japan., Miyanabe K; CMC Regulatory and Analytical R&D., Ono Pharmaceutical Co., Ltd., 1-1, Sakurai 3-chome, Shimamoto-cho, Mishima-gun, Osaka, 618-8585, Japan., Ohbayashi N; Pharmaceutical Research Center, Formulation Research Lab., Meiji Seika Pharma Co., Ltd., 788 Kayama, Odawara, Kanagawa, 250-0852, Japan., Akimaru M; Analytical & Quality Evaluation Research Laboratories, Daiichi Sankyo Co., Ltd., 1-12-1, Shinomiya, Hiratsuka, Kanagawa, 254-0014, Japan., Saito S; Analytical & Quality Evaluation Research Laboratories, Daiichi Sankyo Co., Ltd., 1-12-1, Shinomiya, Hiratsuka, Kanagawa, 254-0014, Japan., Ito D; Japan Blood Products Organization, 1007-31 Izumisawa, Chitose, Hokkaido, 066-8610, Japan., Nakano A; Japan Blood Products Organization, 1007-31 Izumisawa, Chitose, Hokkaido, 066-8610, Japan., Kojima S; Pharmaceutical Laboratory, Mochida Pharmaceutical Co., Ltd. 342 Gensuke, Fujieda, Shizuoka, 426-8640, Japan., Miyahara Y; CMC Modality Technology Laboratories, Production Technology & Supply Chain Management Division, Mitsubishi Tanabe Pharma Corporation, 7473-2, Onoda, Sanyoonoda-shi, Yamaguchi, 756-0054 Japan., Sasaki K; CMC Modality Technology Laboratories, Production Technology & Supply Chain Management Division, Mitsubishi Tanabe Pharma Corporation, 7473-2, Onoda, Sanyoonoda-shi, Yamaguchi, 756-0054 Japan., Maruno T; U-Medico Inc., 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan., Noda M; U-Medico Inc., 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan., Kiyoshi M; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan., Harazono A; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan., Torisu T; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan., Uchiyama S; Department of Biotechnology, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan., Ishii-Watabe A; Division of Biological Chemistry and Biologicals, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.

Publikováno v: Journal of pharmaceutical sciences [J Pharm Sci] 2022 Oct; Vol. 111 (10), pp. 2745-2757. Date of Electronic Publication: 2022 Jul 14.

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Valence tautomerism in a [2 × 2] Co 4 grid complex containing a ditopic arylazo ligand.

Autor: Bonanno NM; Department of Chemistry, Brock University, St. Catharines, ON L2S 3A1, Canada. mlemaire@brocku.ca., Watts Z; Department of Chemistry, Brock University, St. Catharines, ON L2S 3A1, Canada. mlemaire@brocku.ca., Mauws C; Department of Chemistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada., Patrick BO; Department of Chemistry, University of British of Columbia, Vancouver, BC V6T 1Z1, Canada., Wiebe CR; Department of Chemistry, University of Manitoba, Winnipeg, MB R3T 2N2, Canada and Department of Chemistry, University of Winnipeg, Winnipeg, MB R3B 2E9, Canada., Shibano Y; Department of Chemistry and Molecular Materials Science, Graduate School of Science, Osaka City University, Osaka 558 8585, Japan., Sugisaki K; Department of Chemistry and Molecular Materials Science, Graduate School of Science, Osaka City University, Osaka 558 8585, Japan., Matsuoka H; Department of Chemistry and Molecular Materials Science, Graduate School of Science, Osaka City University, Osaka 558 8585, Japan., Shiomi D; Department of Chemistry and Molecular Materials Science, Graduate School of Science, Osaka City University, Osaka 558 8585, Japan., Sato K; Department of Chemistry and Molecular Materials Science, Graduate School of Science, Osaka City University, Osaka 558 8585, Japan., Takui T; Department of Chemistry and Molecular Materials Science, Graduate School of Science, Osaka City University, Osaka 558 8585, Japan., Lemaire MT; Department of Chemistry, Brock University, St. Catharines, ON L2S 3A1, Canada. mlemaire@brocku.ca.

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2021 Jun 22; Vol. 57 (50), pp. 6213-6216.