Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Shibani Pati"'
Autor:
Mark Barry, Alpa Trivedi, Byron Miyazawa, Lindsay R. Vivona, David Shimmin, Praneeti Pathipati, Callie Keane, Joseph Cuschieri, Shibani Pati
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Patients with hemorrhagic shock and trauma (HS/T) are vulnerable to the endotheliopathy of trauma (EOT), characterized by vascular barrier dysfunction, inflammation, and coagulopathy. Cellular therapies such as mesenchymal stem ce
Externí odkaz:
https://doaj.org/article/c8bd7452549440c2bfeb089721eaa409
Autor:
Mark Barry, Shibani Pati
Publikováno v:
Matrix Biology Plus, Vol 14, Iss , Pp 100107- (2022)
Severely injured patients with hemorrhagic shock can develop endothelial dysfunction, systemic inflammation, and coagulation disturbances collectively known as the endotheliopathy of trauma (EOT). Shedding of the endothelial glycocalyx occurs early a
Externí odkaz:
https://doaj.org/article/663da8dd94e84eceb93f41d84c306267
Autor:
Alpa Trivedi, Byron Miyazawa, Stuart Gibb, Kristen Valanoski, Lindsay Vivona, Maximillian Lin, Daniel Potter, Mars Stone, Philip J. Norris, James Murphy, Sawyer Smith, Martin Schreiber, Shibani Pati
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background Cell based therapies, such as bone marrow derived mesenchymal stem cells (BM-MSCs; also known as mesenchymal stromal cells), are currently under investigation for a number of disease applications. The current challenge facing the
Externí odkaz:
https://doaj.org/article/0d26eb3b48944b93917f70bd0e5121f0
Autor:
David F. Stroncek, Ping Jin, David H. McKenna, Minoko Takanashi, Magali J. Fontaine, Shibani Pati, Richard Schäfer, Emily Peterson, Eric Benedetti, Jo-Anna Reems
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
BackgroundCulture-derived mesenchymal stromal cells (MSCs) exhibit variable characteristics when manufactured using different methods and different source materials. The purpose of this study was to assess the impact on MSC characteristics when diffe
Externí odkaz:
https://doaj.org/article/cdc118051f124709981f81630ca9dbaa
Autor:
Shibani Pati, Zhanglong Peng, Katherine Wataha, Byron Miyazawa, Daniel R Potter, Rosemary A Kozar
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192363 (2018)
In severe trauma and hemorrhage the early and empiric use of fresh frozen plasma (FFP) is associated with decreased morbidity and mortality. However, utilization of FFP comes with the significant burden of shipping and storage of frozen blood product
Externí odkaz:
https://doaj.org/article/ddd8b326733e4c18893e2ecfe648913e
Autor:
Shibani Pati, Todd E Rasmussen
Publikováno v:
PLoS Medicine, Vol 14, Iss 7, p e1002343 (2017)
Shibani Pati and Todd Rasmussen summarize progress in preclinical research on cellular therapeutics for traumatic injury and its sequelae and discuss prospects for clinical translation.
Externí odkaz:
https://doaj.org/article/03c5cf374da8415daa956dc8397a90f1
Autor:
Francielle Tramontini Gomes de Sousa Cardozo, Gyulnar Baimukanova, Marion Christine Lanteri, Sheila Marie Keating, Frederico Moraes Ferreira, John Heitman, Cláudio Sérgio Pannuti, Shibani Pati, Camila Malta Romano, Ester Cerdeira Sabino
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178820 (2017)
BACKGROUND:Although most of cases of dengue infections are asymptomatic or mild symptomatic some individuals present warning signs progressing to severe dengue in which plasma leakage is a hallmark. METHODOLOGY/PRINCIPAL FINDINGS:The present study us
Externí odkaz:
https://doaj.org/article/57a5c36c5dfc4838bafcbfb846e7c499
Autor:
Ricky J Haywood-Watson, John B Holcomb, Ernest A Gonzalez, Zhanglong Peng, Shibani Pati, Pyong Woo Park, WeiWei Wang, Ana Maria Zaske, Tyler Menge, Rosemary A Kozar
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23530 (2011)
The early use of fresh frozen plasma as a resuscitative agent after hemorrhagic shock has been associated with improved survival, but the mechanism of protection is unknown. Hemorrhagic shock causes endothelial cell dysfunction and we hypothesized th
Externí odkaz:
https://doaj.org/article/fba98fc882ad4a16a8c324976f0702f9
Autor:
Pramod K Dash, Daniel Johnson, Jordan Clark, Sara A Orsi, Min Zhang, Jing Zhao, Raymond J Grill, Anthony N Moore, Shibani Pati
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24648 (2011)
BACKGROUND: Traumatic brain injury (TBI) sets in motion cascades of biochemical changes that result in delayed cell death and altered neuronal architecture. Studies have demonstrated that inhibition of glycogen synthase kinase-3 (GSK-3) effectively r
Externí odkaz:
https://doaj.org/article/aa94cd3398c34c1e91bf7da3bd93822d
Autor:
Shibani Pati, Michael H Gerber, Tyler D Menge, Kathryn A Wataha, Yuhai Zhao, John Adam Baumgartner, Jing Zhao, Phillip A Letourneau, Maria P Huby, Lisa A Baer, John R Salsbury, Rosemary A Kozar, Charles E Wade, Peter A Walker, Pramod K Dash, Charles S Cox, Marie-Francoise Doursout, John B Holcomb
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25171 (2011)
Hemorrhagic shock (HS) and trauma is currently the leading cause of death in young adults worldwide. Morbidity and mortality after HS and trauma is often the result of multi-organ failure such as acute lung injury (ALI) and acute respiratory distress
Externí odkaz:
https://doaj.org/article/f63b04b85a0f489097f95bfbf74c63cb