Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Shibani Nicum"'
Autor:
Robert D. Morgan, Cristina Ferreras, Isabel Peset, Egle Avizienyte, Andrew G. Renehan, Richard J. Edmondson, Alexander D. Murphy, Shibani Nicum, Thomas Van Brussel, Andrew R. Clamp, Diether Lambrechts, Cong Zhou, Gordon C. Jayson
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Highlights Tissue microarrays and germline DNA from women recruited to the phase 3 trial, ICON7, underwent quantitative immunofluorescence for c-MET/VEGFR-2 co-expression and genetic sequencing for single nucleotide polymorphisms (SNPs) VEGF-pathway
Externí odkaz:
https://doaj.org/article/1954157b03284a32b79f59f1c52385eb
Autor:
Samuel Oxley, Ashwin Kalra, Michail Sideris, Nicole Itzkowitz, Olivia Evans, Emma Christine Atakpa, Adam R. Brentnall, Nina Dworschak, Faiza Gaba, Rhian Gabe, Sudha Sundar, Nick Wood, Shibani Nicum, Alexandra Taylor, Stephen Dobbs, W. Glenn McCluggage, Andy Nordin, Rosa Legood, Sean Kehoe, Sadaf Ghaem-Maghami, Ranjit Manchanda
Publikováno v:
Cancers, Vol 15, Iss 4, p 1273 (2023)
Background: This study aimed to assess the impact of multiple COVID-19 waves on UK gynaecological-oncology services. Methods: An online survey was distributed to all UK-British-Gynaecological-Cancer-Society members during three COVID-19 waves from 20
Externí odkaz:
https://doaj.org/article/32de8e7ea3934bf0adc576ab43bd3f19
Autor:
Sudha Sundar, Andy Nordin, Jo Morrison, Nick Wood, Sadaf Ghaem-Maghami, Jo Nieto, Andrew Phillips, John Butler, Kevin Burton, Rob Gornall, Stephen Dobbs, Rosalind Glasspool, Richard Peevor, Jonathan Ledermann, Iain McNeish, Nithya Ratnavelu, Tim Duncan, Jonathan Frost, Kenneth Lim, Agnieszka Michael, Elly Brockbank, Ketankumar Gajjar, Alexandra Taylor, Rebecca Bowen, Adrian Andreou, Raji Ganesan, Shibani Nicum, Richard Edmondson, Richard Clayton, Janos Balega, Phil Rolland, Hilary Maxwell, Christina Fotopoulou
Publikováno v:
Cancers, Vol 15, Iss 2, p 337 (2023)
Ovarian cancer survival in the UK lags behind comparable countries. Results from the ongoing National Ovarian Cancer Audit feasibility pilot (OCAFP) show that approximately 1 in 4 women with advanced ovarian cancer (Stage 2, 3, 4 and unstaged cancer)
Externí odkaz:
https://doaj.org/article/8196ed148f974bed9f23c4079a7ed8d8
Autor:
Mara Artibani, Kenta Masuda, Zhiyuan Hu, Pascal C. Rauher, Garry Mallett, Nina Wietek, Matteo Morotti, Kay Chong, Mohammad KaramiNejadRanjbar, Christos E. Zois, Sunanda Dhar, Salma El-Sahhar, Leticia Campo, Sarah P. Blagden, Stephen Damato, Pubudu N. Pathiraja, Shibani Nicum, Fergus Gleeson, Alexandros Laios, Abdulkhaliq Alsaadi, Laura Santana Gonzalez, Takeshi Motohara, Ashwag Albukhari, Zhen Lu, Robert C. Bast Jr., Adrian L. Harris, Christer S. Ejsing, Robin W. Klemm, Christopher Yau, Tatjana Sauka-Spengler, Ahmed Ashour Ahmed
Publikováno v:
JCI Insight, Vol 6, Iss 11 (2021)
Similar to tumor-initiating cells (TICs), minimal residual disease (MRD) is capable of reinitiating tumors and causing recurrence. However, the molecular characteristics of solid tumor MRD cells and drivers of their survival have remained elusive. He
Externí odkaz:
https://doaj.org/article/aed4f3377d6c477db1f5a1a0d72b84ea
Autor:
Robert D Morgan, Andrew R Clamp, Bethany M Barnes, Kirsten Timms, Helene Schlecht, Laura Yarram-Smith, Yvonne Wallis, Mikel Valganon-Petrizan, Suzanne MacMahon, Rhian White, Sian Morgan, Sarah McKenna, Emma Hudson, Laura Tookman, Angela George, Ranjit Manchanda, Sudha S Sundar, Shibani Nicum, James D Brenton, Rebecca S Kristeleit, Susana Banerjee, Iain A McNeish, Jonathan A Ledermann, Stephen S Taylor, D Gareth R Evans, Gordon C Jayson
Publikováno v:
Morgan, R D, Clamp, A R, Barnes, B M, Timms, K, Schlecht, H, Yarram-Smith, L, Wallis, Y, Valganon-Petrizan, M, Macmahon, S, White, R, Morgan, S, Mckenna, S, Hudson, E, Tookman, L, George, A, Manchanda, R, Sundar, S S, Nicum, S, Brenton, J D, Kristeleit, R S, Banerjee, S, Mcneish, I A, Ledermann, J A, Taylor, S S, Evans, D G & Jayson, G C 2023, ' Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study ', International Journal of Gynecological Cancer . https://doi.org/10.1136/ijgc-2022-004211
ObjectiveOlaparib plus bevacizumab maintenance therapy improves survival outcomes in women with newly diagnosed, advanced, high-grade ovarian cancer with a deficiency in homologous recombination. We report data from the first year of routine homologo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb793cc9d756983a33fbb917e7372e8
https://doi.org/10.1136/ijgc-2022-004211
https://doi.org/10.1136/ijgc-2022-004211
Autor:
Sarah P. Blagden, David J. Harrison, Nigel W. McCracken, Essam Ghazaly, Hani Gabra, Ajithkumar Sukumaran, Chat Gnanaranjan, Laura Spiers, Rene L. Roux, Shibani Nicum, Farasat Kazmi
Fit of population PK model to observed plasma concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec56fc7327723e59378cbd759a70e3f
https://doi.org/10.1158/1078-0432.22478298.v1
https://doi.org/10.1158/1078-0432.22478298.v1
Autor:
Sarah P. Blagden, David J. Harrison, Nigel W. McCracken, Essam Ghazaly, Hani Gabra, Ajithkumar Sukumaran, Chat Gnanaranjan, Laura Spiers, Rene L. Roux, Shibani Nicum, Farasat Kazmi
Purpose:NUC-1031 is a first-in-class ProTide modification of gemcitabine. In PRO-002, NUC-1031 was combined with carboplatin in recurrent ovarian cancer.Patients and Methods:NUC-1031 was administered on days 1 and 8 with carboplatin on day 1 every 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b5b4eebb189b3aefce230cee6f34e3
https://doi.org/10.1158/1078-0432.c.6529914.v1
https://doi.org/10.1158/1078-0432.c.6529914.v1
Autor:
Sarah P. Blagden, David J. Harrison, Nigel W. McCracken, Essam Ghazaly, Hani Gabra, Ajithkumar Sukumaran, Chat Gnanaranjan, Laura Spiers, Rene L. Roux, Shibani Nicum, Farasat Kazmi
Supplementary Methods and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c0d0ef4e3acfbc76b45a7ca5c62d2b
https://doi.org/10.1158/1078-0432.22478295
https://doi.org/10.1158/1078-0432.22478295
Autor:
Sarah P. Blagden, David J. Harrison, Nigel W. McCracken, Essam Ghazaly, Hani Gabra, Ajithkumar Sukumaran, Chat Gnanaranjan, Laura Spiers, Rene L. Roux, Shibani Nicum, Farasat Kazmi
Supplementary Legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c979b18044c01735fde9e4dae321583
https://doi.org/10.1158/1078-0432.22478292
https://doi.org/10.1158/1078-0432.22478292
Autor:
Ignace Vergote, Antonio Gonzalez-Martin, Domenica Lorusso, Charlie Gourley, Mansoor Raza Mirza, Jean-Emmanuel Kurtz, Aikou Okamoto, Kathleen Moore, Frédéric Kridelka, Iain McNeish, Alexander Reuss, Bénédicte Votan, Andreas du Bois, Sven Mahner, Isabelle Ray-Coquard, Elise C Kohn, Jonathan S Berek, David S P Tan, Nicoletta Colombo, Rongyu Zang, Nicole Concin, Dearbhaile O'Donnell, Alejandro Rauh-Hain, C Simon Herrington, Christian Marth, Andres Poveda, Keiichi Fujiwara, Gavin C E Stuart, Amit M Oza, Michael A Bookman, Christoph Grimm, Regina Berger, Ting-Chang Chang, Kazunori Ochiai, Val Gebski, Alison Davis, Philip Beale, Hannelore Denys, Vincent Vandecaveye, Francisco Jose Candido dos Reis, Maria Del Pilar Estevez Diz, Gavin Stuart, Helen MacKay, Mark Carey, David Cibula, Pavel Dundr (path), Oliver Dorigo, Jonathan Berek, Abu Saadeh, Ingrid Boere, Christianne Lok, Pluvio Coronado, Nelleke Ottevanger, David SP Tan, Joseph Ng, Antonio Gonzalez Martin, Ana Oaknin, Alejandro Perez Fidalgo, Karen Lu, Carlos López-Zavala, Eva María Gómez-García, Xavier Paoletti, Florence Joly, Michael Bookman, Rebecca Arend, Hiroyuki Fujiwara, Kosei Hasegawa, Ilan Bruchim, Dalia Tsoref, Katsutoshi Oda, Takayuki Enomoto, Dayana Michel, Hee-Seung Kim, Jung-Yun Lee, Asima Mukhopadhyay, Dionyssios Katsaros, Sandro Pignata, Giovanni Scambia, Elise Kohn, Jung-Min Lee, Shibani Nicum, Laura Farrelly, Jalid Sehouli, Maren Keller, Elena Braicu, Line Bjørge, Annika Auranen, Stephen Welch, Viola Heinzelmann, Patricia Roxburgh, Ros Glasspool, Jianqing Zhu
Publikováno v:
Lancet Oncology, 23, 8, pp. e374-e384
Vergote, I, Gonzalez-Martin, A, Lorusso, D, Gourley, C, Raza Mirza, M, Kurtz, J-E, Okamoto, A, Moore, K, Kridelka, F, McNeish, I, Reuss, A, Votan, B, du Bois, A, Mahner, S, Ray-Coquard, I, C. Kohn, E, S Berek, J, SP Tan, D, Colombo, N, Zang, R, Concin, N, O'Donnell, D, Rauh-Hain, A, Herrington, C S, Marth, C, Poveda, A, Fujiwara, K, C.E Stuart, G, Oza, A & Bookman, M A 2022, ' Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup ', The Lancet Oncology, vol. 23, no. 8, pp. e374-e384 . https://doi.org/10.1016/S1470-2045(22)00139-5
Lancet Oncology, 23, e374-e384
Vergote, I, Gonzalez-Martin, A, Lorusso, D, Gourley, C, Raza Mirza, M, Kurtz, J-E, Okamoto, A, Moore, K, Kridelka, F, McNeish, I, Reuss, A, Votan, B, du Bois, A, Mahner, S, Ray-Coquard, I, C. Kohn, E, S Berek, J, SP Tan, D, Colombo, N, Zang, R, Concin, N, O'Donnell, D, Rauh-Hain, A, Herrington, C S, Marth, C, Poveda, A, Fujiwara, K, C.E Stuart, G, Oza, A & Bookman, M A 2022, ' Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup ', The Lancet Oncology, vol. 23, no. 8, pp. e374-e384 . https://doi.org/10.1016/S1470-2045(22)00139-5
Lancet Oncology, 23, e374-e384
Contains fulltext : 283536.pdf (Publisher’s version ) (Closed access) The Gynecologic Cancer InterGroup (GCIG) sixth Ovarian Cancer Conference on Clinical Research was held virtually in October, 2021, following published consensus guidelines. The g