Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shiba S Dandpat"'
A nascent riboswitch helix orchestrates robust transcriptional regulation through signal integration
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Widespread manganese-sensing transcriptional riboswitches effect the dependable gene regulation needed for bacterial manganese homeostasis in changing environments. Riboswitches – like most structured RNAs – are believed to fold co-trans
Externí odkaz:
https://doaj.org/article/192d7aa34a3749128124d8df373bc39b
Autor:
Krishna C. Suddala, Ian R. Price, Shiba S. Dandpat, Michal Janeček, Petra Kührová, Jiří Šponer, Pavel Banáš, Ailong Ke, Nils G. Walter
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Riboswitches bind intracellular metabolites and control bacterial gene expression. Here, by using X-ray crystallography, molecular dynamics simulations, and single-molecule fluorescence resonance energy transfer, the authors show how a local Mn2+ ion
Externí odkaz:
https://doaj.org/article/a105e074773f48059aba90c0f77a1c51
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Transcriptional riboswitches involve RNA aptamers that are typically found in the 5′ untranslated regions (UTRs) of bacterial mRNAs and form alternative secondary structures upon binding to cognate ligands. Alteration of the riboswitch's secondary
Externí odkaz:
https://doaj.org/article/59ba54e728554486be11dba23521db04
Publikováno v:
Nucleic Acids Research. 50:8818-8833
Noncoding, structured 5′-untranslated regions (5′-UTRs) of bacterial messenger RNAs (mRNAs) can control translation efficiency by forming structures that either recruit or repel the ribosome. Here we exploit a 5′-UTR embedded preQ1-sensing, pse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42f29ff5097e216ab6cb1f3b842bd44
https://doi.org/10.1093/nar/gkac635
https://doi.org/10.1093/nar/gkac635
Publikováno v:
Biophysical Journal. 122:443a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83d30b49dc26cde491762c4c69f966f0
https://doi.org/10.1016/j.bpj.2022.11.2393
https://doi.org/10.1016/j.bpj.2022.11.2393
Publikováno v:
International Journal of Molecular Sciences. 24:2668
Understanding complex biological events at the molecular level paves the path to determine mechanistic processes across the timescale necessary for breakthrough discoveries. While various conventional biophysical methods provide some information for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63f1c31f2a1b7ec02b1ee7df5e3d645b
https://doi.org/10.3390/ijms24032668
https://doi.org/10.3390/ijms24032668
Autor:
Ian R. Price, Krishna C. Suddala, Pavel Banáš, Shiba S. Dandpat, Nils G. Walter, Jiří Šponer, Ailong Ke, Petra Kührová, Michal Janeček
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The widespread Mn2+-sensing yybP-ykoY riboswitch controls the expression of bacterial Mn2+ homeostasis genes. Here, we first determine the crystal structure of the ligand-bound yybP-ykoY riboswitch aptamer from Xanthomonas oryzae at 2.96 A resolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b48af29a00d031b4faa09f5c13e4dda7
https://doaj.org/article/a105e074773f48059aba90c0f77a1c51
https://doaj.org/article/a105e074773f48059aba90c0f77a1c51
Noncoding, structured 5’- untranslated regions (5’-UTRs) of messenger RNAs (mRNAs) control translation efficiency by forming structures that can either recruit or repel the ribosome. Here we exploit a bacterial, preQ1-sensing translational ribosw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25be263163c2e374c6c55ef97c0bca64
https://doi.org/10.21203/rs.3.rs-551111/v1
https://doi.org/10.21203/rs.3.rs-551111/v1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences
Transcriptional riboswitches involve RNA aptamers that are typically found in the 5′ untranslated regions (UTRs) of bacterial mRNAs and form alternative secondary structures upon binding to cognate ligands. Alteration of the riboswitch's secondary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1a26fab7a00962e2e9d960731dc5196
https://www.frontiersin.org/articles/10.3389/fmolb.2020.607158/full
https://www.frontiersin.org/articles/10.3389/fmolb.2020.607158/full
Autor:
Shiba S. Dandpat, Jiří Šponer, Nils G. Walter, Ailong Ke, Ian R. Price, Petra Kührová, Pavel Banáš, Krishna C. Suddala, Michal Janeček
The widespread manganese-ion sensing yybP-ykoY riboswitch controls the expression of bacterial Mn2+ homeostasis genes. Here, we first determine the crystal structure of the ligand-bound yybP-ykoY riboswitch from Xanthomonas oryzae at 2.85 Å resoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48464322a1370dc61c0b19b4c1ff9d9
https://doi.org/10.1101/553354
https://doi.org/10.1101/553354