Breast cancer cells induce cancer-associated fibroblasts to secrete hepatocyte growth factor to enhance breast tumorigenesis.

Autor: Shiaw-Wei Tyan, Wen-Hung Kuo, Chun-Kai Huang, Chi-Chun Pan, Jin-Yuh Shew, King-Jen Chang, Eva Y-H P Lee, Wen-Hwa Lee

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e15313 (2011)

It has been well documented that microenvironment consisting of stroma affects breast cancer progression. However, the mechanisms by which cancer cells and fibroblasts, the major cell type in stroma, interact with each other during tumor development

Externí odkaz: https://doaj.org/article/14dec0fdbf0842359c72116852fd352a

Characterization of the Role of XpsM Protein in the Type II Secretion Pathway of Xanthomonas campestris pv. campestris

Autor: Shiaw-Wei Tyan, 田孝威

87
Gram-negative bacteria have developed different pathways to secrete proteins into the extracellular melieu. In the type II secretion pathway, secretion occurs in two steps: the secreted proteins are first exported through the Sec-dependent me

Externí odkaz: http://ndltd.ncl.edu.tw/handle/49786826967064694274

Serum- and glucocorticoid-inducible kinase (SGK) is a target of the MAPK/ERK signaling pathway that mediates memory formation in rats

Autor: Ching-Tien Lee, Ming-Chi Tsai, Eminy H.Y. Lee, Shiaw-Wei Tyan, Ying C. Yang, Yun L. Ma

Publikováno v: European Journal of Neuroscience. 23:1311-1320

We have previously demonstrated that serum- and glucocorticoid-inducible kinase (SGK) plays a causal role in facilitating memory formation of spatial learning in rats, but the SGK signaling pathway involved in spatial memory formation is not known. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2316c5f761b8f1d2d648baf805e6a6c
https://doi.org/10.1111/j.1460-9568.2006.04650.x

Involvement of the XpsN Protein in Formation of the XpsL-XpsM Complex in Xanthomonas campestris pv. campestris Type II Secretion Apparatus

Autor: Wei-Ming Leu, Hsien-Ming Lee, David Chanhen Chen, Shiaw-Wei Tyan, Ling-Yun Chen, Nien-Tai Hu

Publikováno v: Journal of Bacteriology. 183:528-535

The xps gene cluster is required for the second step of type II protein secretion in Xanthomonas campestris pv. campestris. Deletion of the entire gene cluster caused accumulation of secreted proteins in the periplasm. By analyzing protein abundance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d5d08e515de19c5f06a8896100dac7
https://doi.org/10.1128/jb.183.2.528-535.2001

Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change

Autor: Wen-Hwa Lee, Kai-Lin Peng, Wen-Hung Kuo, Jin-Yuh Shew, Li-Jung Juan, Shiaw-Wei Tyan, Chih-Hung Hsu, Eva Y.-H. P. Lee, Chun-Chin Chen, King-Jen Chang

Publikováno v: PLoS ONE, Vol 7, Iss 4, p e35128 (2012)
PLoS ONE
Tyan, Shiaw-Wei; Hsu, Chih-Hung; Peng, Kai-Lin; Chen, Chun-Chin; Kuo, Wen-Hung; Lee, Eva P.; et al.(2012). Breast Cancer Cells Induce Stromal Fibroblasts to Secrete ADAMTS1 for Cancer Invasion through an Epigenetic Change. PLoS ONE, 7(4), e35128. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6mg5r1z1

Microenvironment plays an important role in cancer development. We have reported that the cancer-associated stromal cells exhibit phenotypic and functional changes compared to stromal cells neighboring to normal tissues. However, the molecular mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db01b371382c8497aebc021b258fbef3
http://europepmc.org/articles/PMC3325931?pdf=render