Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Shiaw Lin Wu"'
Autor:
Bernice Yeung, Lionel Sison, Siyang Peter Li, Xuesong Scott Li, Christopher S. Barton, Shiaw-Lin Wu, Brian Flaherty, Qiaozhen Lu
Publikováno v:
Analytical Chemistry. 92:8306-8314
Characterization of the higher-order structures in idursulfase (iduronate-2-sulfatase, I2S) has been accomplished through the use of hydrogen-deuterium exchange mass spectrometry (HDX-MS). The method has over 97% sequence coverage, including seven of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc473d39d05aa39ece71b1f5cb1ff9e
https://doi.org/10.1021/acs.analchem.0c00661
https://doi.org/10.1021/acs.analchem.0c00661
Autor:
Xiaomin Song, Bin Li, Yan Xiao, Chunxia Chen, Qiang Wang, Yujie Liu, Alan Berezov, Chen Xu, Yayi Gao, Zhiyuan Li, Shiaw-Lin Wu, Zheng Cai, Hongtao Zhang, Barry L. Karger, Wayne W. Hancock, Andrew D. Wells, Zhaocai Zhou, Mark I. Greene
Publikováno v:
Cell Reports, Vol 1, Iss 6, Pp 665-675 (2012)
FOXP3 is a key transcription factor for regulatory T cell function. We report the crystal structure of the FOXP3 coiled-coil domain, through which a loose or transient dimeric association is formed and modulated, accounting for the activity variation
Externí odkaz:
https://doaj.org/article/fcde7d29afb943fca110e332fa7543d3
Publikováno v:
Amino Acids. 51:1353-1363
Interferons are signaling proteins that belong to the large class of cytokines and human interferons which are classified based on the type of receptor interactions: type I, II and III. IFNα2b belongs to the type I interferon class with a major ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f1d5297034c958576ce485765660ef
https://doi.org/10.1007/s00726-019-02772-9
https://doi.org/10.1007/s00726-019-02772-9
Autor:
Di Wu, Shiaw-Lin Wu, Nicholas J. Mozdzierz, Kerry R. Love, J. Christopher Love, Yu Annie Wang, Jared R. Auclair, Yang Tang, William S. Hancock, Jeffrey N. Agar, Kartik A. Shah, Joseph P. Salisbury, Richa Sarin, Anna Fan Zhang
Publikováno v:
Analytical Chemistry. 89:12771-12777
With the advent of biosimilars to the U.S. market, it is important to have better analytical tools to ensure product quality from batch to batch. In addition, the recent popularity of using a continuous process for production of biopharmaceuticals, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e391c6c4b2e0c3eba3ca7ac2f650dc1b
https://doi.org/10.1021/acs.analchem.7b03026
https://doi.org/10.1021/acs.analchem.7b03026
Publikováno v:
Analytical Chemistry. 89:11036-11043
Influenza hemagglutinin is a surface glycoprotein related to virus invasion and host immune system response. Understanding site specific glycosylation of hemagglutinin will increase our knowledge about virus evolution and can improve the design and q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f3958604f5318e2d62f12d33d7af89
https://doi.org/10.1021/acs.analchem.7b03025
https://doi.org/10.1021/acs.analchem.7b03025
Publikováno v:
Biologicals. 45:93-95
Capture reagents are critical to affinity-based bioanalytical methods. The potential bias of capture reagents, for or against certain subpopulations of the target of interest, may lead to inaccurate quantitation. This issue is more profound for sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babbbfa98b5e435e900e4dc73d8440de
https://doi.org/10.1016/j.biologicals.2016.09.014
https://doi.org/10.1016/j.biologicals.2016.09.014
Publikováno v:
Protein Analysis using Mass Spectrometry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bf70a31314ce30a04d616825de73adc
https://doi.org/10.1002/9781119371779.ch3
https://doi.org/10.1002/9781119371779.ch3
Autor:
Shiaw Lin Wu, William S. Hancock, Shan Qin, Anna Fan Zhang, Jordan A. Kreidberg, Yunjoon Jung
Publikováno v:
Journal of Proteome Research. 13:4901-4909
Autosomal dominant polycystic kidney disease (ADPKD) is a common genetic disorder caused by mutations in the Pkd1 or Pkd2 genes, in which large cysts replace normal kidney tissue, leading to end-stage kidney disease. In this study we have utilized a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f814de5920708a53e5e7c4a3a2955ef
https://doi.org/10.1021/pr5009702
https://doi.org/10.1021/pr5009702
Autor:
Michael Snyder, Emma Yue Zhang, William S. Hancock, Rui Chen, Shiaw-Lin Wu, Hogune Im, Rajasree Menon, Gilbert S. Omenn
Publikováno v:
Journal of Proteome Research. 13:212-227
This study was conducted as a part of the Chromosome-Centric Human Proteome Project (C-HPP) of the Human Proteome Organization. The United States team of C-HPP is focused on characterizing the protein-coding genes in chromosome 17. Despite its small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b59af835401d22f8550f28ac509bfe6
https://doi.org/10.1021/pr400773v
https://doi.org/10.1021/pr400773v
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 80:126-135
Liquid chromatography-tandem mass spectrometry-based proteomics for peptide mapping and sequencing was used to characterize the marketed monoclonal antibody trastuzumab and compare it with two biosimilar products, mAb A containing D359E and L361M var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc4ffd4518e60815c6a5fcc41c3e00b9
https://doi.org/10.1016/j.jpba.2013.02.040
https://doi.org/10.1016/j.jpba.2013.02.040