Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Shian-Ren Lin"'
Autor:
Chih-Hao Fang, Ya Fang Cheng, Shian-Ren Lin, Wan-Yu Lai, Li-Ren Liao, Yen-Ling Chiu, Jan-Mou Lee
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Lytic Epstein–Barr virus (EBV) infection plays a major role in the pathogenesis of nasopharyngeal carcinoma (NPC). For patients with recurrent or metastatic NPC and resistant to conventional therapies, adoptive cell therapy usin
Externí odkaz:
https://doaj.org/article/228dd9d1e6fe49869158254df1b7702b
Autor:
Yu-Ching Wen, Yen-Nien Liu, Hsiu-Lien Yeh, Wei-Hao Chen, Kuo-Ching Jiang, Shian-Ren Lin, Jiaoti Huang, Michael Hsiao, Wei-Yu Chen
Publikováno v:
Oncogenesis, Vol 10, Iss 11, Pp 1-11 (2021)
Abstract Neuroendocrine differentiation (NED) is associated with WNT signaling activation and can be significantly observed after failure of androgen-deprivation therapy (ADT) for prostatic adenocarcinomas. Cytokine signaling is stimulated in NED pro
Externí odkaz:
https://doaj.org/article/99d5960710964c0a90f14edae6b01add
Autor:
Jan-Mou Lee, Yi-Ping Hung, Kai-Yuan Chou, Cheng-Yun Lee, Shian-Ren Lin, Ya-Han Tsai, Wan-Yu Lai, Yu-Yun Shao, Chiun Hsu, Chih-Hung Hsu, Yee Chao
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Immune checkpoint inhibitors (ICI) have been applied in treating advanced hepatocellular carcinoma (aHCC) patients, but few patients exhibit stable and lasting responses. Moreover, identifying aHCC patients suitable for ICI treatment is still challen
Externí odkaz:
https://doaj.org/article/c071b1bfc5434aa39197581cde706abc
Autor:
Wei-Jun Chiu, Chun-Shu Lin, Shian-Ren Lin, Ting-Hsu Chen, Chia-Jen Wu, Prabhakar Busa, Hui Long, Ching-Cheng Chen, Feng-Jen Tseng, Yaw-Syan Fu, Ching-Feng Weng
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113443- (2022)
16-hydroxycleroda-3,13-dien-15,16-olide (HCD) has antitumor activity reported in numerous types of cancers. However, the efficacy of HCD treatment in non-small-cell lung cancer (NSCLC) cells and doxorubicin-resistant (Dox-R)-NSCLC cells remains to be
Externí odkaz:
https://doaj.org/article/047af3e938e14c759f9ac48002bf6db3
Autor:
Wei-Yu Chen, Yu-Ching Wen, Shian-Ren Lin, Hsiu-Lien Yeh, Kuo-Ching Jiang, Wei-Hao Chen, Yow-Sien Lin, Qingfu Zhang, Phui-Ly Liew, Michael Hsiao, Jiaoti Huang, Yen-Nien Liu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Here, the authors discover that NGF, upregulated by transcription factor ZBTB46 in prostate cancer exposed to androgen therapy, promotes neuroendocrine differentiation. They show that NGF interacts with the GPCR CHRM4, that both NGF and CHRM4 are upr
Externí odkaz:
https://doaj.org/article/e7b7c66702104de49414ef8b54df1488
Autor:
Sih-Pei Chen, Shian-Ren Lin, Ting-Hsu Chen, Hui-Suan Ng, Hip-Seng Yim, Max K. Leong, Ching-Feng Weng
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 144, Iss , Pp 112333- (2021)
Diabetes mellitus (DM) is concomitant with significant morbidity and mortality and its prevalence is accumulative in worldwide. The conventional antidiabetic agents are known to mitigate the symptoms of diabetes; however, they may also cause side and
Externí odkaz:
https://doaj.org/article/4e4f22de34fa41f6b02b82a8d0a0d198
Autor:
Shian-Ren Lin, Chia-Hsiang Chang, May-Jwan Tsai, Henrich Cheng, Jian-Chyi Chen, Max K. Leong, Ching-Feng Weng
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 10 (2019)
Dipeptidyl peptidase IV (DPP-4), an incretin glucagon-like peptide-1 (GLP-1) degrading enzyme, contains two forms and it can exert various physiological functions particular in controlling blood glucose through the action of GLP-1. In diabetic use, t
Externí odkaz:
https://doaj.org/article/c0af3a3e37b04e739513de9d7f63efde
Publikováno v:
Molecules, Vol 25, Iss 10, p 2380 (2020)
Prostate cancer (PCa) is one of the most prevalent and malignant cancer types in men, which causes more than three-hundred thousand cancer death each year. At late stage of PCa progression, bone marrow is the most often metastatic site that constitut
Externí odkaz:
https://doaj.org/article/b4120c0dd2b2469c8583c53bc5de7476
Autor:
Jia-Huei Zheng, Shian-Ren Lin, Feng-Jen Tseng, May-Jywan Tsai, Sheng-I Lue, Yi-Chen Chia, Mindar Woon, Yaw-Syan Fu, Ching-Feng Weng
Publikováno v:
Biomolecules, Vol 9, Iss 12, p 762 (2019)
Inflammatory bowel disease (IBD) is general term for ulcerative colitis and Crohn’s disease, which is chronic intestinal and colorectal inflammation caused by microbial infiltration or immunocyte attack. IBD is not curable, and is highly susceptibl
Externí odkaz:
https://doaj.org/article/d9c6c9e5aa00468c82083158d4f6f4a8
Autor:
Dinh-Chuong Pham, Yu-Chuan Chang, Shian-Ren Lin, Yuh-Ming Fuh, May-Jywan Tsai, Ching-Feng Weng
Publikováno v:
Molecules, Vol 23, Iss 12, p 3110 (2018)
Human neuroblastoma cancer is the most typical extracranial solid tumor. Yet, new remedial treatment therapies are demanded to overcome its sluggish survival rate. Neferine, isolated from the lotus embryos, inhibits the proliferation of various cance
Externí odkaz:
https://doaj.org/article/2305821d80a84e54b200311a42c01da7