Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shiam-Peng Tay"'
Autor:
Kah-Leong Lim, Steven P. Gygi, Esther Wong, Donald S. Kirkpatrick, Olga Pletnikova, Jeanne M.M. Tan, Juan C. Troncoso, Ted M. Dawson, Shiam Peng Tay, Valina L. Dawson, Han Seok Ko, Michelle W L Ho, Michael K. Lee
Publikováno v:
Human Molecular Genetics. 17:431-439
Although ubiquitin-enriched protein inclusions represent an almost invariant feature of neurodegenerative diseases, the mechanism underlying their biogenesis remains unclear. In particular, whether the topology of ubiquitin linkages influences the dy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67e6ae6dc3ad4667a31ea50b2ea59a5
https://doi.org/10.1093/hmg/ddm320
https://doi.org/10.1093/hmg/ddm320
Autor:
Kah-Leong Lim, Cheng Wang, Norazean Zaiden, Shiam-Peng Tay, Han Seok Ko, Valina L. Dawson, Jeanne M.M. Tan, Zhenshui Zhang, Esther Wong, Ted M. Dawson
Publikováno v:
Journal of Biological Chemistry. 282:12310-12318
Loss of parkin function is a predominant cause of familial Parkinsonism. Emerging evidence also suggests that parkin expression variability may confer a risk for sporadic Parkinson disease. We have recently demonstrated that a wide variety of Parkins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348eef790f3d063863b2e9ded8626c89
https://doi.org/10.1074/jbc.m609466200
https://doi.org/10.1074/jbc.m609466200
Autor:
Shiam Peng Tay, Cheng Wang, Bobby Thomas, Han Seok Ko, Fai Tsang, Katherine C. M. Chew, Michelle W L Ho, Juan C. Troncoso, Tit Meng Lim, Ted M. Dawson, Olga Pletnikova, Tuck Wah Soong, Kah-Leong Lim, Valina L. Dawson
Publikováno v:
Human Molecular Genetics. 14:3885-3897
Mutations in parkin are currently recognized as the most common cause of familial Parkinsonism. Emerging evidence also suggests that parkin expression variability may confer a risk for the development of the more common, sporadic form of Parkinson's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bc87978a301bed1a43dd3d66e6b046
https://doi.org/10.1093/hmg/ddi413
https://doi.org/10.1093/hmg/ddi413
Publikováno v:
Etiology and Pathophysiology of Parkinson's Disease
Parkinson’s disease (PD) is the most common neurodegenerative movement disorder affecting millions of predominantly elderly individuals worldwide. Originally described as “The Shaking Palsy” in 1817 by the British physician, James Parkinson, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ae48aa571f1f3ceb2897a9d6bcf9356
http://www.intechopen.com/articles/show/title/parkin-and-parkinson-s-disease
http://www.intechopen.com/articles/show/title/parkin-and-parkinson-s-disease
Autor:
Jian-Xiong Sung, Kah-Leong Lim, Shiam-Peng Tay, Puay Hoon Tan, Hui-Mei Tan, Jeanne M.M. Tan, Carol Tang, Daniel L.H. Yip, Siew Heng Wong, Boon-Huat Bay, Chou Chai, Alex X.Y. Ang, Pei Jou Chua, Calvin W.S. Yeo
Publikováno v:
The Journal of biological chemistry. 285(38)
Although mutations in the parkin gene are frequently associated with familial Parkinsonism, emerging evidence suggests that parkin also plays a role in cancers as a putative tumor suppressor. Supporting this, we show here that parkin expression is dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33188a915f847aa71e4d09d5b53e80c
https://pubmed.ncbi.nlm.nih.gov/20630868
https://pubmed.ncbi.nlm.nih.gov/20630868
Autor:
Wong, Esther S. P.1, Tan, Jeanne M. M.1,2, Cheng Wang1,3, Zhenshui Zhang1, Shiam-Peng Tay1,4, Zaiden, Norazean1, Han Seok Ko2, Dawson, Valina L.2, Dawson, Ted M.2, Kah-Leong Lim1,3,5 Kah_Leong_Lim@nni.com.sg
Publikováno v:
Journal of Biological Chemistry. 4/20/2007, Vol. 282 Issue 16, p12310-12318. 9p. 3 Black and White Photographs, 1 Diagram, 6 Graphs.