Výsledky vyhledávání - "Shi-hao Zhou"

Akademický článek

Performance analysis of non-invasive prenatal testing for trisomy 13, 18, and 21: A large-scale retrospective study (2018–2021)

Autor: Yu-shan Lu, Ying-ying Chen, Si-yi Ding, Li Zeng, Liang-cheng Shi, Yu-jiao Li, Jing-jing Zhang, Jin Fu, Shi-hao Zhou, Jun He

Publikováno v: Heliyon, Vol 10, Iss 13, Pp e33437- (2024)

Background: Non-invasive prenatal tests (NIPT) are used to screen for trisomy 21, 18, and 13. This study investigated NIPT performance and the clinical significance of its results. Methods: Pregnant women (n = 282,911) participating in a free NIPT (A

Externí odkaz: https://doaj.org/article/d431c55aa9c34740a505218bb29fa80a

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Akademický článek

Lack of gene flow between Phytophthora infestans populations of two neighboring countries with the largest potato production

Autor: Yan‐Ping Wang, Jia‐Hui Xie, E‐Jiao Wu, Lurwanu Yahuza, Guo‐Hua Duan, Lin‐Lin Shen, Hao Liu, Shi‐Hao Zhou, Oswald Nkurikiyimfura, Björn Andersson, Li‐Na Yang, Li‐Ping Shang, Wen Zhu, Jiasui Zhan

Publikováno v: Evolutionary Applications, Vol 13, Iss 2, Pp 318-329 (2020)

Abstract Gene flow is an important evolutionary force that enables adaptive responses of plant pathogens in response to changes in the environment and plant disease management strategies. In this study, we made a direct inference concerning gene flow

Externí odkaz: https://doaj.org/article/27450e3887614183a0c32ae3a8878cc7

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Akademický článek

Alum Adjuvant and Built-in TLR7 Agonist Synergistically Enhance Anti-MUC1 Immune Responses for Cancer Vaccine

Autor: Shi-Hao Zhou, Yu-Ting Li, Ru-Yan Zhang, Yan-Ling Liu, Zi-Wei You, Miao-Miao Bian, Yu Wen, Jian Wang, Jing-Jing Du, Jun Guo

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

The tumor-associated antigen mucin 1 (MUC1) is an attractive target of antitumor vaccine, but its weak immunogenicity is a big challenge for the development of vaccine. In order to enhance immune responses against MUC1, herein, we conjugated small mo

Externí odkaz: https://doaj.org/article/0517683d82744606ac67b555f04e1829

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Akademický článek

MUC1 Specific Immune Responses Enhanced by Coadministration of Liposomal DDA/MPLA and Lipoglycopeptide

Autor: Jing-Jing Du, Shi-Hao Zhou, Zi-Ru Cheng, Wen-Bo Xu, Ru-Yan Zhang, Long-Sheng Wang, Jun Guo

Publikováno v: Frontiers in Chemistry, Vol 10 (2022)

Mucin 1 (MUC1), a well-known tumor-associated antigen and attractive target for tumor immunotherapy, is overexpressed in most human epithelial adenomas with aberrant glycosylation. However, its low immunogenicity impedes the development of MUC1-targe

Externí odkaz: https://doaj.org/article/d27accaeee4643ec905d356559f76d60

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Akademický článek

Multifunctional Protein Conjugates with Built-in Adjuvant (Adjuvant-Protein-Antigen) as Cancer Vaccines Boost Potent Immune Responses

Autor: Jing-Jing Du, Chang-Wei Wang, Wen-Bo Xu, Lian Zhang, Yuan-Kai Tang, Shi-Hao Zhou, Xiao-Fei Gao, Guang-Fu Yang, Jun Guo

Publikováno v: iScience, Vol 23, Iss 3, Pp - (2020)

Summary: Many cancer vaccines are not successful in clinical trials, mainly due to the challenges associated with breaking immune tolerance. Herein, we report a new strategy using an adjuvant-protein-antigen (three-in-one protein conjugates with buil

Externí odkaz: https://doaj.org/article/3e48a30e6b4d450ca93dda5ba1c61f46

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