Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Shi-You Chen"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) remains the most common cause of liver disease in the United States due to the increased incidence of metabolic dysfunction and obesity. Surfactant protein A (SPA) regulates ma
Externí odkaz:
https://doaj.org/article/83f6772c4d63418ca277b650b46eed12
Autor:
Yan Wang, Yun Liu, Xing‐yuan Li, Lu‐yuan Yao, MagdaleenaNaemi Mbadhi, Shao‐Juan Chen, Yan‐xia Lv, Xin Bao, Long Chen, Shi‐You Chen, Jing‐xuan Zhang, Yan Wu, Jing Lv, Liu‐liu Shi, Jun‐ming Tang
Publikováno v:
ESC Heart Failure, Vol 10, Iss 6, Pp 3311-3329 (2023)
Abstract Aims We aim to explore the role and mechanism of vagus nerve stimulation (VNS) in coronary endothelial cells and angiogenesis in infarcted hearts. Methods and results Seven days after rat myocardial infarction (MI) was prepared by ligation o
Externí odkaz:
https://doaj.org/article/80ad4fe9d18246a2be38e758465cf133
Autor:
Dunpeng Cai, Shi-You Chen
Publikováno v:
Cells, Vol 13, Iss 15, p 1257 (2024)
Vascular smooth muscle cells (VSMCs) play a critical role in maintaining vascular integrity. VSMC dysfunction leads to numerous vascular diseases. Adenosine deaminases acting on RNA 1 (ADAR1), an RNA editing enzyme, has shown both RNA editing and non
Externí odkaz:
https://doaj.org/article/e71f5dec57514d2eb481b7baeec519f4
Autor:
Ruo-nan Zhang, Xin Bao, Yun Liu, Yan Wang, Xing-Yuan Li, Ge Tan, Magdaleena Naemi Mbadhi, Wei Xu, Qian Yang, Lu-yuan Yao, Long Chen, Xiao-ying Zhao, Chang-qing Hu, Jing-xuan Zhang, Hong-tao Zheng, Yan Wu, Shan Li, Shao-juan Chen, Shi-you Chen, Jing Lv, Liu-liu Shi, Jun-ming Tang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-21 (2023)
Abstract Background Clinically, Charcot-Marie-Tooth disease (CMT)-associated muscle atrophy still lacks effective treatment. Deletion and mutation of L-periaxin can be involved in CMT type 4F (CMT4F) by destroying the myelin sheath form, which may be
Externí odkaz:
https://doaj.org/article/1a41198738f24ee3ae2dee872f02231b
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102903- (2023)
Astrocytes affect stroke outcomes by acquiring functionally dominant phenotypes. Understanding molecular mechanisms dictating astrocyte functional status after brain ischemia/reperfusion may reveal new therapeutic strategies. Adenosine deaminase acti
Externí odkaz:
https://doaj.org/article/a59b2061d0224badb14f8862fe26c1c8
Autor:
Jing Yue, Wei Xu, Li Xiang, Shao-juan Chen, Xin-yuan Li, Qian Yang, Ruo-nan Zhang, Xin Bao, Yan Wang, MagdaleenaNaemi Mbadhi, Yun Liu, Lu-yuan Yao, Long Chen, Xiao-ying Zhao, Chang-qing Hu, Jing-xuan Zhang, Hong-tao Zheng, Yan Wu, Shi-You Chen, Shan Li, Jing Lv, Liu-liu Shi, Jun-ming Tang
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract We aimed to explore whether superfluous sympathetic activity affects myoblast differentiation, fusion, and myofiber types using a continuous single-dose isoprenaline exposure model in vitro and to further confirm the role of distinct NFATs i
Externí odkaz:
https://doaj.org/article/c80f763b2e8046b9aa81a0addab7a234
Autor:
Linfang Zhang, Xiujuan Xia, Hao Wu, Xuanyou Liu, Qiang Zhu, Meifang Wang, Hong Hao, Yuqi Cui, De-Pei Li, Shi-You Chen, Luis A. Martinez-Lemus, Michael A. Hill, Canxia Xu, Zhenguo Liu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
BackgroundSubstantial sex differences exist in atherosclerosis. Excessive reactive oxygen species (ROS) formation could lead to endothelial dysfunction which is critical to atherosclerosis development and progression. Helicobacter pylori (H. pylori)
Externí odkaz:
https://doaj.org/article/22e29d190e62472b88e4d50867b430c2
Autor:
Decha Pinkaew, Erik Martinez-Hackert, Wei Jia, Matthew D. King, Fei Miao, Nicole R. Enger, Runglawan Silakit, Kota Ramana, Shi-You Chen, Ken Fujise
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
Fortilin prevents the activation of the TGF-β1 receptor by occupying the pocket of TGF-β1 and competing with TGF-βRII to bind with TGF-β1. This inhibits Smad3 phosphorylation and the differentiation of C3H10T1/2 mesenchymal progenitor cells to sm
Externí odkaz:
https://doaj.org/article/5e135eec35ad4b54abfbb03df6f53892
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
IntroductionAs a multisystem autoimmune disorder disease, systemic sclerosis (SSc) is characterized by inflammation and fibrosis in the skin and other internal organs. However, mechanisms underlying the inflammatory response that drives the developme
Externí odkaz:
https://doaj.org/article/442c0a3eb62742a7b76c837ec1e8ec3f
Autor:
Dunpeng Cai, Shi-You Chen
Publikováno v:
Redox Biology, Vol 58, Iss , Pp 102524- (2022)
Pulmonary hypertension (PH) induced by chronic hypoxia is characterized by thickening of pulmonary artery walls, elevated pulmonary vascular resistance, and right-heart failure. Dysfunction of endothelial cells is the hallmark event in the progressio
Externí odkaz:
https://doaj.org/article/d8c81a79194f419690d1678c0c87ddf0