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AMP010014A09 in Sus Scrofa Encodes an Analog of G Protein-Coupled Receptor 109A, Which Mediates the Anti-Inflammatory Effects of Beta-Hydroxybutyric Acid

Autor: Guangxin Chen, Wenqian Feng, Shi-Yao Xu, Shoupeng Fu, Bingxu Huang, Juxiong Liu, Wei Wang

Publikováno v: Cellular Physiology and Biochemistry, Vol 42, Iss 4, Pp 1420-1430 (2017)

Background: Hydroxy-carboxylic acid receptor 2 (HCA2, also called GPR109A) belongs to the G protein-coupled receptor (GPCR) family and is found in humans, rats, mice, hamsters and guinea pigs, but there are almost no reports of this protein in other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe6009a090aab45a227ac9e881c064e
http://www.karger.com/Article/FullText/479206

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AG and UAG induce β-casein expression via activation of ERK1/2 and AKT pathways

Autor: Ying-Jie Gao, Su-Nan Li, Qing-Kang Lv, Dongxue Yang, Juxiong Liu, Chuan Zhang, Bingxu Huang, Shi-Yao Xu, Wei Wang, Yalong Zeng

Publikováno v: Journal of Molecular Endocrinology

The ghrelin peptides were found to circulate in two major forms: acylated ghrelin (AG) and unacylated ghrelin (UAG). Previous studies showed that AG regulates β-casein (CSN2) expression in mammary epithelial cells. However, little is known about the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa82ffba966a6ffd58f3920f30dbdcf5
https://doi.org/10.1530/jme-15-0287

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Mycophenolate Mofetil Modulates Differentiation of Th1/Th2 and the Secretion of Cytokines in an Active Crohn’s Disease Mouse Model

Autor: Ying-Jie Gao, Juxiong Liu, Zi-Peng Xu, Shi-Yao Xu, Wei Wang, Su-Nan Li, Qing-Kang Lv, Yalong Zeng, Bingxu Huang, Yan Lv, Dianfeng Liu, Dongxue Yang

Publikováno v: International Journal of Molecular Sciences, Vol 16, Iss 11, Pp 26654-26666 (2015)
International Journal of Molecular Sciences
Volume 16
Issue 11
Pages 26654-26666
International Journal of Molecular Sciences; Volume 16; Issue 11; Pages: 26654-26666

Mycophenolate mofetil (MMF) is an alternative immunosuppressive agent that has been reported to be effective and well tolerated for the treatment of refractory inflammatory bowel disease (IBD). The aim of this study was to investigate the therapeutic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b42b7059bdc4f60c6918980904f414
https://doi.org/10.3390/ijms161125985

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Licochalcone A Prevents the Loss of Dopaminergic Neurons by Inhibiting Microglial Activation in Lipopolysaccharide (LPS)-Induced Parkinson’s Disease Models

Autor: Dianfeng Liu, Yalong Zeng, Xuan Yan, Juxiong Liu, Guangxin Chen, Shi-Yao Xu, Dongxue Yang, Bingxu Huang, Shoupeng Fu, Wei Wang, Chen Ju

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 10, p 2043 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 10; Pages: 2043
International Journal of Molecular Sciences

The neuroprotective effects of Licochalcone A (Lico.A), a flavonoid isolated from the herb licorice, in Parkinson's disease (PD) have not been elucidated. The prominent pathological feature of PD is the loss of dopaminergic neurons. The crucial role

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac4d0f2cd35aeca433b2545b3c9320e
https://www.mdpi.com/1422-0067/18/10/2043

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GLP-2 Attenuates LPS-Induced Inflammation in BV-2 Cells by Inhibiting ERK1/2, JNK1/2 and NF-κB Signaling Pathways

Autor: Ying-Jie Gao, Shoupeng Fu, Su-Nan Li, Juxiong Liu, Wen-Zhi Ren, Bo-Wen Liu, Wei Wang, Nan Li, Shi-Yao Xu, Yalong Zeng, Xuan Yan, Dianfeng Liu

Publikováno v: International Journal of Molecular Sciences; Volume 17; Issue 2; Pages: 190
International Journal of Molecular Sciences, Vol 17, Iss 2, p 190 (2016)
International Journal of Molecular Sciences

The pathogenesis of Parkinson’s disease (PD) often involves the over-activation of microglia. Over-activated microglia could produce several inflammatory mediators, which trigger excessive inflammation and ultimately cause dopaminergic neuron damag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adeb356b021b6ad7ce287186d9fbb81

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Vanillin Protects Dopaminergic Neurons against Inflammation-Mediated Cell Death by Inhibiting ERK1/2, P38 and the NF-κB Signaling Pathway

Autor: Dianfeng Liu, Xuan Yan, Guangxin Chen, Wen-Zhi Ren, Juxiong Liu, Dong Liu, Shoupeng Fu, Shi-Yao Xu, Wei Wang, Bingxu Huang, Xiang-Yang Zhang

Publikováno v: International Journal of Molecular Sciences, Vol 18, Iss 2, p 389 (2017)
International Journal of Molecular Sciences; Volume 18; Issue 2; Pages: 389
International Journal of Molecular Sciences

Neuroinflammation plays a very important role in the pathogenesis of Parkinson's disease (PD). After activation, microglia produce pro-inflammatory mediators that damage surrounding neurons. Consequently, the inhibition of microglial activation might

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::037f6632c44ab4bdaa51d6d143ca785a
https://doi.org/10.3390/ijms18020389

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