Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shi-Xing Ma"'
Autor:
Hua Miao, Fei Liu, Yan-Ni Wang, Xiao-Yong Yu, Shougang Zhuang, Yan Guo, Nosratola D. Vaziri, Shi-Xing Ma, Wei Su, You-Quan Shang, Ming Gao, Jin-Hua Zhang, Li Zhang, Ying-Yong Zhao, Gang Cao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-18 (2024)
Abstract Accumulated evidence suggested that gut microbial dysbiosis interplayed with progressive chronic kidney disease (CKD). However, no available therapy is effective in suppressing progressive CKD. Here, using microbiomics in 480 participants in
Externí odkaz:
https://doaj.org/article/f0388e0061014d22b8856082a830360e
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e20019- (2023)
Considerable achievements were realized in illuminating underlying pathological mechanisms of patients with idiopathic membranous nephropathy (IMN). Although IMN patients are well diagnosed before they reach renal failure, no currently available drug
Externí odkaz:
https://doaj.org/article/aec8ec286241441cbcfa051382bf7efe
Autor:
Dan-Qian Chen, Gang Cao, Hua Chen, Christos P. Argyopoulos, Hui Yu, Wei Su, Lin Chen, David C. Samuels, Shougang Zhuang, George P. Bayliss, Shilin Zhao, Xiao-Yong Yu, Nosratola D. Vaziri, Ming Wang, Dan Liu, Jia-Rong Mao, Shi-Xing Ma, Jin Zhao, Yuan Zhang, You-Quan Shang, Huining Kang, Fei Ye, Xiao-Hong Cheng, Xiang-Ri Li, Li Zhang, Mei-Xia Meng, Yan Guo, Ying-Yong Zhao
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Accurate monitoring of chronic kidney disease (CKD) progression is essential for efficient disease management. Here Chen et al. identify five serum metabolites in patients with stage 1–5 CKD whose levels associate with disease progression, and find
Externí odkaz:
https://doaj.org/article/4a04997a433f49e4a807e4cf744638af
Autor:
Xia-Qing Wu, Ying-Yong Zhao, Hua Miao, Xiao-Yong Yu, Yan-Long Zhao, Dan-Qian Chen, Wei Su, Yuan Zhang, Shougang Zhuang, Yan Guo, You-Quan Shang, Jia-Rong Mao, Jin Zhao, Nosratola D. Vaziri, Ming Gao, Huan-Qiao Zhang, Gang Cao, Yan-Ni Wang, Li Zhang, Shi-Xing Ma, Jin-Hua Zhang, Lin Chen
Publikováno v:
British Journal of Pharmacology. 179:103-124
BACKGROUND AND PURPOSE In chronic kidney disease (CKD), patients inevitably reach end-stage renal disease and require renal transplant. Evidence suggests that CKD is associated with metabolite disorders. However, the molecular pathways targeted by me
Autor:
Qing-Quan Liu, Yuan-Yuan Chen, Yan-Ni Wang, Lin Chen, Shi-Xing Ma, Ying-Yong Zhao, Bao-Li Liu
Publikováno v:
Clinica Chimica Acta. 499:54-63
Chronic kidney disease (CKD), characterized as renal dysfunction, is recognized as a major public health problem with high morbidity and mortality worldwide. Unfortunately, there are no obvious clinical symptoms in early stage disease until severe da
Publikováno v:
Clinica Chimica Acta. 491:59-65
Chronic kidney disease (CKD) results in high morbidity and mortality worldwide causing a huge socioeconomic burden. MicroRNA (miRNA) exert critical regulatory functions by targeting downstream genes and have been associated with many pathophysiologic
Autor:
Xiao-Hong Cheng, Lin Chen, Xiao-Yong Yu, Nosratola D. Vaziri, Hua Chen, Mei-Xia Meng, Ying-Yong Zhao, Ming Wang, Gang Cao, Li Zhang, Wei Su, Dan Liu, You-Quan Shang, Xiang-Ri Li, Shi-Xing Ma, Hui Yu, Fei Ye, Shougang Zhuang, David C. Samuels, George Bayliss, Shilin Zhao, Huining Kang, Yuan Zhang, Christos P. Argyopoulos, Jin Zhao, Jia-Rong Mao, Yan Guo, Dan-Qian Chen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Chen, Dan-Qian; Cao, Gang; Chen, Hua; Argyopoulos, Christos P; Yu, Hui; Su, Wei; et al.(2019). Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.. Nature communications, 10(1), 1476. doi: 10.1038/s41467-019-09329-0. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9v2177nc
Nature communications, vol 10, iss 1
Nature Communications
Chen, Dan-Qian; Cao, Gang; Chen, Hua; Argyopoulos, Christos P; Yu, Hui; Su, Wei; et al.(2019). Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.. Nature communications, 10(1), 1476. doi: 10.1038/s41467-019-09329-0. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9v2177nc
Nature communications, vol 10, iss 1
Nature Communications
Early detection and accurate monitoring of chronic kidney disease (CKD) could improve care and retard progression to end-stage renal disease. Here, using untargeted metabolomics in 2155 participants including patients with stage 1–5 CKD and healthy
Publikováno v:
Journal of Nephrology Advances. 1:4-14
Renal fibrosis was a chronic and progressive process affecting kidneys in chronic kidney disease (CKD), regardless of cause. Although no effective targeted therapy yet existed to retard renal fibrosis, a number of important recent advances have highl
Autor:
You-Quan Shang, Xiao-Yong Yu, Ying-Yong Zhao, Wei Su, Ya-Long Feng, Hua Chen, Jia-Rong Mao, Yan Guo, Dan-Qian Chen, Li Zhang, Shi-Xing Ma, Nosratola D. Vaziri
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease, vol 1865, iss 9
Feng, Ya-Long; Chen, Hua; Chen, Dan-Qian; Vaziri, Nosratola D; Su, Wei; Ma, Shi-Xing; et al.(2019). Activated NF-κB/Nrf2 and Wnt/β-catenin pathways are associated with lipid metabolism in CKD patients with microalbuminuria and macroalbuminuria.. Biochimica et biophysica acta. Molecular basis of disease. doi: 10.1016/j.bbadis.2019.05.010. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/148046wd
Feng, Ya-Long; Chen, Hua; Chen, Dan-Qian; Vaziri, Nosratola D; Su, Wei; Ma, Shi-Xing; et al.(2019). Activated NF-κB/Nrf2 and Wnt/β-catenin pathways are associated with lipid metabolism in CKD patients with microalbuminuria and macroalbuminuria.. Biochimica et biophysica acta. Molecular basis of disease. doi: 10.1016/j.bbadis.2019.05.010. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/148046wd
Early diagnosis of CKD patients at risk for microalbuminuria or macroalbuminuria could facilitate clinical outcomes and long-term survival. Considering the few and limited efficacy of current biomarkers in early detection, we aim to discover plasma l