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Small antibody mimetics comprising two complementarity-determining regions and a framework region for tumor targeting

Autor: Xiao-Qing Qiu, Shi-Tao Yue, Bei Cai, He Wang, Lan-Lan Wang

Publikováno v: Nature Biotechnology. 25:921-929

Here we show that fusion of two complementarity-determining regions (CDRs), VHCDR1 and VLCDR3, through a cognate framework region (VHFR2) yields mimetics that retain the antigen recognition of their parent molecules, but have a superior capacity to p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3166a4e37484114a6f5e2031f25476d5
https://doi.org/10.1038/nbt1320

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Effects of qian-kun-nin, a Chinese herbal medicine formulation, on HIV positive subjects: a pilot study

Autor: Yong-Xin Xue, Shi-Tao Yue, Anoja S. Attele, Liu Zhang, Chun-Su Yuan

Publikováno v: The American journal of Chinese medicine. 28(3-4)

Qian-Kun-Nin is a Chinese herbal formulation considered to have anti-infection, anti-tumor and immuno-enhancing properties. Data from previous investigations showed that Qian-Kun-Nin causes HIV growth inhibition and immunomodulation in vitro, suggest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173f4b563bcbcc2bd62550deda5cf45e
https://pubmed.ncbi.nlm.nih.gov/11154043

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