Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shi-Rui Fan"'
Autor:
Ting Ruan, Zheng-Rui Xiang, Yun-Wu Zhang, Shi-Rui Fan, Juan Ren, Qian Zhao, Xiao-Long Sun, Shi-Li Wu, Li-Li Xu, Miao Qiao, Chen-Xu Jing, Xiao-Jiang Hao, Duo-Zhi Chen
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
IntroductionCurrently, the development of new antiviral drugs against COVID-19 remains of significant importance. In traditional Chinese medicine, the herb Euphorbia fischeriana Steud is often used for antiviral treatment, yet its therapeutic effect
Externí odkaz:
https://doaj.org/article/a7f1cbd90ce5409081fae224ff5970a8
Autor:
Jie-Yun Cai, Bi-Juan Yang, Xiao-Jiang Hao, Jing-Jing Guo, Shi-Rui Fan, Yi-Ting Wang, Xin-Fang Zhang, Duo-Zhi Chen
Publikováno v:
Natural Product Research. 36:2473-2478
Two new cycloartane triterpenoids, (24 R)-cycloartane-3β,24,25,30-tetrol (1) and (24 R)-24,25,30-trihydroxy-9,19-cycloartane-3-one (2), along with three known compounds (3-5) were isolated from leaves and twigs of Aphanamixis polystachya. The new co
Autor:
Jie-Yun Cai, Jing-Jing Guo, Bi-Juan Yang, Yi-Ting Wang, Shi-Rui Fan, Chen-xu Jing, Duo-Zhi Chen, Xiao-Jiang Hao
Publikováno v:
The Journal of Organic Chemistry. 85:8597-8602
Aphananoid A, a limonoid which features a rare C24 appendage and new 5/6/5 fused-ring framework, was obtained from Aphanamixis polystachya. The planar structure as well as the absolute configuration was identified based on extensive spectroscopic ana
Autor:
Bi-juan Yang, Shi-rui Fan, Xin-fang Zhang, Jie-yun Cai, Ting Ruan, Zheng-rui Xiang, Juan Ren, Xiao-jiang Hao, Duo-zhi Chen
Publikováno v:
Bioorganic chemistry. 119
Humans have been suffering from vitiligo for a long time. Target vitiligo drugs have yet been approved. Activation of Wnt/β-catenin signalling has potential in the therapeutic use of vitiligo, so exploring new drugs that specifically directly activa
Autor:
Shi-Rui Fan, Xiao-Jiang Hao, Xiaoli He, Bi-Juan Yang, Lin Li, Duo-Zhi Chen, Yu Zhang, Jie-Yun Cai, Chen-xu Jing, Heng Zhang
Publikováno v:
Bioorganic Chemistry. 84:285-294
Phenanthridine derivativeHLY78 has previously been identified as the first Wnt/β-catenin signalling pathway agonist that targets the DAX domain of axin. However, due to the relatively weak activation on the Wnt/β-catenin signalling pathway, HLY78 i
Publikováno v:
Natural Product Research. 34:3328-3334
Two new lignans (1–2), along with five known compounds (3-7) with different structures were isolated from leaves and twigs of Cleistanthus concinnus Croizat. The new lignans were elucidated as (7′R,8′S)-3,3′,5′-trimethoxy-4,4′-dihydroxy-7
Autor:
Xiao-Jiang Hao, Chen-xu Jing, Shi-Rui Fan, Jie-Yun Cai, Yan-Qiu Yuze, Duo-Zhi Chen, Miao Luo, Huochun Yao, Zihao Pan, Yi-Ting Wang, Bi-Juan Yang, Guangjin Liu
Publikováno v:
Journal of natural products. 84(4)
Porcine epidemic diarrhea virus (PEDV) has become increasingly problematic around the world, not only for its hazards to livestock but also due to the possibility that it is a zoonotic disease. Although vaccine therapy has made some progress toward P
Autor:
Chen-xu Jing, Bi-Juan Yang, Jie-Yun Cai, Xiao-Jiang Hao, Xueying Lu, Yi-Ting Wang, Li Lin, Deng Zang, Xin-Fang Zhang, Haji Akber Aisa, Duo-Zhi Chen, Shi-Rui Fan
Background and Purpose: Humans have been fighting vitiligo for centuries but still being inferior due to the lack of efficiency drugs and therapies. While some research has implied the therapeutic potential of Wnt/β-catenin signalling on curing viti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9bfc0c75df7e774b8f40dc9e461a16c
https://doi.org/10.22541/au.160581793.37973769/v1
https://doi.org/10.22541/au.160581793.37973769/v1
Autor:
Bi-Juan, Yang, Shi-Rui, Fan, Jie-Yun, Cai, Yi-Ting, Wang, Chen-Xu, Jing, Jing-Jing, Guo, Duo-Zhi, Chen, Xiao-Jiang, Hao
Publikováno v:
The Journal of organic chemistry. 85(13)
Aphananoid A, a limonoid which features a rare C
Autor:
Lian Yang, Chen-xu Jing, Yong-Tang Zheng, Jie-Yun Cai, Ting Ruan, Xin-Yan Long, Yi-Ting Wang, Juan Ren, Xiao-Jiang Hao, Rong-Hua Luo, Xin-Fang Zhang, Duo-Zhi Chen, Xiao Ding, Shi-Rui Fan, Bi-Juan Yang
Publikováno v:
European Journal of Medicinal Chemistry
The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unprecedented in human history. As a major structural protein, nucleocapsid protein (NPro) is critical to the replication of SARS-CoV-2. In this work, 17