Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Shi-Qiong Xu"'
Autor:
Simone Buraschi, Alaide Morcavallo, Thomas Neill, Manuela Stefanello, Chiara Palladino, Shi-Qiong Xu, Antonino Belfiore, Renato V. Iozzo, Andrea Morrione
Publikováno v:
Matrix Biology Plus, Vol 6, Iss , Pp 100022- (2020)
Bladder cancer is one of the most common and aggressive cancers and, regardless of the treatment, often recurs and metastasizes. Thus, a better understanding of the mechanisms regulating urothelial tumorigenesis is critical for the design and impleme
Externí odkaz:
https://doaj.org/article/cb38a426bf8b46ac96fb4f0ebad3ce01
Autor:
Ryuta Tanimoto, Koujung G Lu, Shi-Qiong Xu, Simone Buraschi, Antonino Belfiore, Renato V Iozzo, Andrea Morrione
Publikováno v:
Frontiers in Endocrinology, Vol 7 (2016)
The growth factor progranulin has emerged in recent years as a critical regulator of transformation in several cancer models, including breast cancer, glioblastomas, leukemias and hepatocellular carcinomas. Several laboratories, including ours, have
Externí odkaz:
https://doaj.org/article/9930673af12d4b709854abc8202ca7f5
Autor:
Marco Genua, Shi-Qiong Xu, Simone Buraschi, Stephen C Peiper, Leonard G Gomella, Antonino Belfiore, Renato V Iozzo, Andrea Morrione
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40148 (2012)
The insulin-like growth factor receptor I (IGF-IR) plays an essential role in transformation by promoting cell growth and protecting cancer cells from apoptosis. We have recently demonstrated that the IGF-IR is overexpressed in invasive bladder cance
Externí odkaz:
https://doaj.org/article/534ece6ed05246f5946d372f7940c188
Autor:
Andrea Morrione, Renato V. Iozzo, Antonino Belfiore, Simone Buraschi, Chiara Palladino, Shi-Qiong Xu, Thomas Neill
Publikováno v:
Matrix Biol
The growth factor progranulin plays a critical role in bladder cancer by modulating tumor cell motility and invasion. Progranulin regulates remodeling of the actin cytoskeleton by interacting with drebrin, an actin binding protein that regulates tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87468851fd80faf673b1de45bc710e20
https://pubmed.ncbi.nlm.nih.gov/32417448
https://pubmed.ncbi.nlm.nih.gov/32417448
Autor:
Andrea Morrione, Chiara Palladino, Simone Buraschi, Leonard G. Gomella, Ryuta Tanimoto, Thomas Neill, Antonino Belfiore, Renato V. Iozzo, Stephen C. Peiper, Shi Qiong Xu
Publikováno v:
Matrix Biology. 64:27-39
Despite extensive clinical and experimental studies over the past decades, the pathogenesis and progression to the castration-resistant stage of prostate cancer remains largely unknown. Progranulin, a secreted growth factor, strongly binds the hepari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8babe25947cc8bac9f981f4e04a94e
https://doi.org/10.1016/j.matbio.2017.04.001
https://doi.org/10.1016/j.matbio.2017.04.001
Autor:
Andrea Morrione, Igor Moskalev, Ruth Birbe, Alaide Morcavallo, Ryuta Tanimoto, Shi Qiong Xu, Leonard G. Gomella, Marco Genua, Renato V. Iozzo, Antonino Belfiore, Peter C. Black, Simone Buraschi, Stephen C. Peiper, Manuela Stefanello
Publikováno v:
Scopus-Elsevier
Oncotarget
Oncotarget
We have recently demonstrated a critical role for progranulin in bladder cancer. Progranulin contributes, as an autocrine growth factor, to the transformed phenotype by modulating Akt-and MAPK-driven motility, invasion and anchorage-independent growt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53085012126ada43d71517e5645ac9cf
https://doi.org/10.18632/oncotarget.9556
https://doi.org/10.18632/oncotarget.9556
Autor:
Andrea Morrione, Antonino Belfiore, Shi-Qiong Xu, Manuela Stefanello, Renato V. Iozzo, Alaide Morcavallo, Chiara Palladino, Simone Buraschi, Thomas Neill
Publikováno v:
Matrix Biology Plus, Vol 6, Iss, Pp 100022-(2020)
Matrix Biology Plus
Matrix Biology Plus
Bladder cancer is one of the most common and aggressive cancers and, regardless of the treatment, often recurs and metastasizes. Thus, a better understanding of the mechanisms regulating urothelial tumorigenesis is critical for the design and impleme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf1b0f2b0e69bd002cf5839ef09244b
https://doi.org/10.1016/j.mbplus.2020.100022
https://doi.org/10.1016/j.mbplus.2020.100022
Autor:
Andrea Morrione, Manuela Stefanello, Ryuta Tanimoto, Shi Qiong Xu, Antonino Belfiore, Renato V. Iozzo, Simone Buraschi
Publikováno v:
Methods in Molecular Biology ISBN: 9781493985579
Methods Mol Biol
Methods Mol Biol
Progranulin has emerged in recent years as an important regulator of various biological functions including cell proliferation, wound healing, motility, and protection from apoptosis. Progranulin is also critical for transformation as established in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9f638b2e0d3efaa91f78641afeb7cb
https://doi.org/10.1007/978-1-4939-8559-3_9
https://doi.org/10.1007/978-1-4939-8559-3_9
Autor:
Alaide Morcavallo, Antonino Belfiore, Ryuta Tanimoto, Renato V. Iozzo, Simone Buraschi, Kuojung G. Lu, Katia Scotlandi, Manuela Stefanello, Demetrius H. Bagley, Shi Qiong Xu, Leonard G. Gomella, Andrea Morrione, Mario Terracciano
Publikováno v:
Endocrinology. 156:58-70
The growth factor progranulin is as an important regulator of transformation in several cellular systems. We have previously demonstrated that progranulin acts as an autocrine growth factor and stimulates motility, proliferation, and anchorage-indepe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c54ea038b5908400fc2581d2c561463
https://doi.org/10.1210/en.2014-1590
https://doi.org/10.1210/en.2014-1590
Autor:
Ryuta Tanimoto, Renato V. Iozzo, Andrea Morrione, Chiara Palladino, Antonino Belfiore, Leonard G. Gomella, Simone Buraschi, Shi-Qiong Xu
Introduction and Objective: Despite extensive clinical and experimental studies over the past decades, the pathogenesis of prostate cancer remains largely unknown. Furthermore, the mechanisms promoting the castration-resistant stage of prostate cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3bffa2f5475f7327453e3dbbb93f8e
http://hdl.handle.net/20.500.11769/499991
http://hdl.handle.net/20.500.11769/499991