Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Shi-Hui Dong"'
Autor:
Meng Wang, Wen-Wei Li, Zhe Cao, Jianong Sun, Jiang Xiong, Si-Qin Tao, Tinghong Lv, Kun Gao, Shangwen Luo, Shi-Hui Dong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2773-2785 (2024)
Although sulfonation plays crucial roles in various biological processes and is frequently utilized in medicinal chemistry to improve water solubility and chemical diversity of drug leads, it is rare and underexplored in ribosomally synthesized and p
Externí odkaz:
https://doaj.org/article/84a41eb575904bcd99a71dc741b27604
Autor:
Dan Xue, Ethan A. Older, Zheng Zhong, Zhuo Shang, Nanzhu Chen, Nolan Dittenhauser, Lukuan Hou, Peiyan Cai, Michael D. Walla, Shi-Hui Dong, Xiaoyu Tang, Hexin Chen, Prakash Nagarkatti, Mitzi Nagarkatti, Yong-Xin Li, Jie Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Many natural product biosynthetic gene clusters are found not to harbor a full set of necessary genes and must utilize enzymes encoded elsewhere (hidden) in the genome for biosynthesis. Here, the authors establish a global correlation network bridgin
Externí odkaz:
https://doaj.org/article/2d45458728b04eb68e62d0cf806fd907
Publikováno v:
ACS Central Science, Vol 5, Iss 5, Pp 842-851 (2019)
Externí odkaz:
https://doaj.org/article/49db7bfcc29c44a788c2b899246a9876
Autor:
Dipti D Nayak, Andi Liu, Neha Agrawal, Roy Rodriguez-Carerro, Shi-Hui Dong, Douglas A Mitchell, Satish K Nair, William W Metcalf
Publikováno v:
PLoS Biology, Vol 18, Iss 2, p e3000507 (2020)
The enzyme methyl-coenzyme M reductase (MCR) plays an important role in mediating global levels of methane by catalyzing a reversible reaction that leads to the production or consumption of this potent greenhouse gas in methanogenic and methanotrophi
Externí odkaz:
https://doaj.org/article/c5e074b9ed204ef29e0c3b33b2436ccb
Autor:
Silvia C Bobeica, Shi-Hui Dong, Liujie Huo, Nuria Mazo, Martin I McLaughlin, Gonzalo Jiménez-Osés, Satish K Nair, Wilfred A van der Donk
Publikováno v:
eLife, Vol 8 (2019)
The secretion of peptides and proteins is essential for survival and ecological adaptation of bacteria. Dual-functional ATP-binding cassette transporters export antimicrobial or quorum signaling peptides in Gram-positive bacteria. Their substrates co
Externí odkaz:
https://doaj.org/article/58cff56211d94a92b6b6271733263552
Autor:
Shangwen Luo, Shi-Hui Dong
Publikováno v:
Molecules, Vol 24, Iss 8, p 1541 (2019)
Natural products have played indispensable roles in drug development and biomedical research. Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a group of fast-expanding natural products attribute to genome mining efforts
Externí odkaz:
https://doaj.org/article/62243b18bd524cfb9eff9332a779872c
Publikováno v:
eLife, Vol 4 (2015)
The enterococcal cytolysin is a virulence factor consisting of two post-translationally modified peptides that synergistically kill human immune cells. Both peptides are made by CylM, a member of the LanM lanthipeptide synthetases. CylM catalyzes sev
Externí odkaz:
https://doaj.org/article/0add9a4c4b1d4a7f87310ecbe2b42f65
Publikováno v:
電腦學刊. 33:197-211
Aiming at the problems of low accuracy, poor real-time performance and large cumulative error in traditional depth camera visual synchronization positioning and map construction algorithms, this paper proposes an improved visual SLAM algorithm for mo
Autor:
Sha-Sha Zhang, Jiang Xiong, Jiao-Jiao Cui, Kai-Liang Ma, Wen-Liang Wu, Ya Li, Shangwen Luo, Kun Gao, Shi-Hui Dong
Publikováno v:
Organic Letters. 24:2226-2231
Autor:
Jiang Xiong, Shangwen Luo, Cheng-Xiao Qin, Jiao-Jiao Cui, Yu-Xia Ma, Meng-Xue Guo, Sha-Sha Zhang, Ya Li, Kun Gao, Shi-Hui Dong
Publikováno v:
Organic Letters. 24:1518-1523
Thioamitides are apoptosis-inducing ribosomally synthesized and post-translationally modified peptides (RiPPs) with substantial post-translational modifications (PTMs), whose biosynthetic details remain elusive. We reconstituted their key PTMs throug