Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Shi-Hsia Hwa"'
Autor:
Hylton E. Rodel, Isabella A. T. M. Ferreira, Carly G. K. Ziegler, Yashica Ganga, Mallory Bernstein, Shi-Hsia Hwa, Kievershen Nargan, Gila Lustig, Gilla Kaplan, Mahdad Noursadeghi, Alex K. Shalek, Adrie J. C. Steyn, Alex Sigal
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Mycobacterium tuberculosis (Mtb) bacilli readily aggregate. We previously reported that Mtb aggregates lead to phagocyte death and subsequent efficient replication in the dead infected cells. Here, we examined the transcriptional response of human mo
Externí odkaz:
https://doaj.org/article/2c87105ebf6a454b849cec67673a9715
Autor:
Shi-Hsia Hwa, Yock Ann Lee, Joseph N Brewoo, Charalambos D Partidos, Jorge E Osorio, Joseph D Santangelo
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 11, p e2538 (2013)
Human enterovirus 71 (EV71) is a significant cause of morbidity and mortality from Hand, Foot and Mouth Disease (HFMD) and neurological complications, particularly in young children in the Asia-Pacific region. There are no vaccines or antiviral thera
Externí odkaz:
https://doaj.org/article/eeb616478f0b4a30941c4fb365f20f6c
Autor:
Chee Wah Tan, Wan Ni Chia, Feng Zhu, Barnaby E. Young, Napaporn Chantasrisawad, Shi-Hsia Hwa, Aileen Ying-Yan Yeoh, Beng Lee Lim, Wee Chee Yap, Surinder Kaur M. S. Pada, Seow Yen Tan, Watsamon Jantarabenjakul, Lim Kai Toh, Shiwei Chen, Jinyan Zhang, Yun Yan Mah, Vivian Chih-Wei Chen, Mark I-C Chen, Supaporn Wacharapluesadee, Alex Sigal, Opass Putcharoen, David Chien Lye, Lin-Fa Wang
Publikováno v:
Nature Microbiology
The SARS-CoV-2 Omicron variant (B.1.1.529 lineage) escapes antibodies that neutralize the ancestral virus. We tested human serum panels from participants with differing infection and vaccination status using a multiplex surrogate virus neutralization
Akademický článek
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Autor:
Anthonet L. Koen, Alane Izu, Vicky Baillie, Gaurav Kwatra, Clare L. Cutland, Lee Fairlie, Sherman D. Padayachee, Keertan Dheda, Shaun L. Barnabas, Qasim Ebrahim Bhorat, Carmen Briner, Khatija Ahmed, Sutika Bhikha, Jinal N. Bhiman, Jeanine du Plessis, Aliasgar Esmail, Elizea Horne, Shi-Hsia Hwa, Aylin Oommen-Jose, Teresa Lambe, Matt Laubscher, Mookho Malahleha, Gabriella Benade, Shakeel McKenzie, Suzette Oelofse, Faeezah Patel, Sureshnee Pillay, Sarah Rhead, Hylton Rodel, Carol Taoushanis, Houriiyah Tegally, Asha Thombrayil, Tonya L. Villafana, Sarah Gilbert, Andrew J. Pollard, Shabir A. Madhi
In this South African phase 1/2b study, we demonstrated vaccine efficacy (VE) of two doses of AZD1222 for asymptomatic and symptomatic SARS-CoV-2 infection: 90.6% against wild-type and 77.1% against the Delta variant ≥9 months after vaccination. VE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90f5a6d20644392d1f0fb82c06d8b6c8
https://doi.org/10.1101/2022.07.18.22277743
https://doi.org/10.1101/2022.07.18.22277743
Autor:
Shabir A, Madhi, Vicky, Baillie, Clare L, Cutland, Merryn, Voysey, Anthonet L, Koen, Lee, Fairlie, Sherman D, Padayachee, Keertan, Dheda, Shaun L, Barnabas, Qasim E, Bhorat, Carmen, Briner, Gaurav, Kwatra, Khatija, Ahmed, Parvinder, Aley, Sutika, Bhikha, Jinal N, Bhiman, As'ad E, Bhorat, Jeanine, du Plessis, Aliasgar, Esmail, Marisa, Groenewald, Elizea, Horne, Shi-Hsia, Hwa, Aylin, Jose, Teresa, Lambe, Matt, Laubscher, Mookho, Malahleha, Masebole, Masenya, Mduduzi, Masilela, Shakeel, McKenzie, Kgaogelo, Molapo, Andrew, Moultrie, Suzette, Oelofse, Faeezah, Patel, Sureshnee, Pillay, Sarah, Rhead, Hylton, Rodel, Lindie, Rossouw, Carol, Taoushanis, Houriiyah, Tegally, Asha, Thombrayil, Samuel, van Eck, Constantinos K, Wibmer, Nicholas M, Durham, Elizabeth J, Kelly, Tonya L, Villafana, Sarah, Gilbert, Andrew J, Pollard, Tulio, de Oliveira, Penny L, Moore, Alex, Sigal, Alane, Izu, Peter, Zuidewind
Publikováno v:
The New England Journal of Medicine : NEJM / Publ. by the Massachusetts Medical Society
Background Assessment of the safety and efficacy of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in different populations is essential, as is investigation of the efficacy of the vaccines against emerging SARS-CoV
Autor:
Shi-Hsia, Hwa, Jumari, Snyman, Mallory, Bernstein, Yashica, Ganga, Sandile, Cele, Daniel, Muema, Chee Wah, Tan, Khadija, Khan, Farina, Karim, Willem, Hanekom, Leslie, Bernstein, Stefan H E, Kaufmann, Lin-Fa, Wang, Thumbi, Ndung'u, Alex, Sigal
Publikováno v:
The Journal of infectious diseases.
SARS-CoV-2 infection may be associated with worse clinical outcomes in people with HIV (PWH). We report anti-SARS-CoV-2 antibody responses in COVID-19 hospitalized patients in Durban, South Africa during the second SARS-CoV-2 infection wave dominated
Differential escape of neutralizing antibodies by SARS-CoV-2 Omicron and pre-emergent sarbecoviruses
Autor:
Lin-Fa Wang, Chee Wah Tan, Wan Ni Chia, Feng Zhu, Barnaby Young, Napaporn Chantasrisawad, Shi-Hsia Hwa, Aileen Ying-Yan Yeoh, Beng Lee Lim, Wee Chee Yap, Surinder Kaur Pada, Seow Yen Tan, Watsamon Jantarabenjakul, Shiwei Chen, Jinyan Zhang, Yun Yan Mah, Vivian Chen, Mark Chen, Supaporn Wacharapluesadee, COMMIT-KZN Team, Opass Putcharoen, David Lye
Publikováno v:
Research square.
The SARS-CoV-2 B.1.1.529 lineage, Omicron variant, was first detected in November 2021 and carries 32 amino acid mutations in the spike protein (15 in RBD) and exhibits significant escape of neutralizing antibodies targeting the parental SARS-CoV-2 v
Autor:
Sandile Cele, Laurelle Jackson, David S. Khoury, Khadija Khan, Thandeka Moyo-Gwete, Houriiyah Tegally, James Emmanuel San, Deborah Cromer, Cathrine Scheepers, Daniel Amoako, Farina Karim, Mallory Bernstein, Gila Lustig, Derseree Archary, Muneerah Smith, Yashica Ganga, Zesuliwe Jule, Kajal Reedoy, Shi-Hsia Hwa, Jennifer Giandhari, Jonathan M. Blackburn, Bernadett I. Gosnell, Salim S. Abdool Karim, Willem Hanekom, null Network for Genomic Surveillance in, null COMMIT-KZN Team, Anne von Gottberg, Jinal Bhiman, Richard J. Lessells, Mahomed-Yunus S. Moosa, Miles P. Davenport, Tulio de Oliveira, Penny L. Moore, Alex Sigal
Publikováno v:
Nature.
Autor:
Shi-Hsia Hwa, Khadija Khan, Tandile Hermanus, Alex Sigal, Farina Karim, Yashica Ganga, Willem A. Hanekom, Ntombifuthi Mthabela, Bernadett I Gosnell, Wesley C. Van Voorhis, Penny L. Moore, Houriiyah Tegally, Eduan Wilkinson, Salim S. Abdool Karim, San Emmanuel James, Tulio de Oliveira, Jumari Snyman, Sasha W Tilles, Jennifer Giandhari, Sandile Cele, Thumbi Ndung'u, Mahomed-Yunus S. Moosa, Mallory Bernstein, Gila Lustig, Matilda Mazibuko, Richard J Lessells
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
Summary Characterizing SARS-CoV-2 evolution in specific geographies may help predict the properties of variants coming from these regions. We mapped neutralization of a SARS-CoV-2 strain that evolved over 6 months from the ancestral virus in a person
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f12cd667e378b0f39e1e0c3e0aa6c07d
https://doi.org/10.1101/2021.09.14.21263564
https://doi.org/10.1101/2021.09.14.21263564