Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Shi Zhong Luo"'
Publikováno v:
Supramolecular Materials, Vol 3, Iss , Pp 100050- (2024)
Protein functionality hinges on precise three-dimensional structures, while molecular chaperones orchestrate folding, proteome maintenance, and proteostasis. Recent attention has focused on BRICHOS domain from pro-proteins of pulmonary surfactant pro
Externí odkaz:
https://doaj.org/article/a721af9123a8473fbd3ed6ab841eaf06
Autor:
Xiaolin Yu, Guangfei Duan, Pengfei Pei, Long Chen, Renji Gu, Wenrui Hu, Hongli Zhang, Yan-Dong Wang, Lili Gong, Lihong Liu, Ting-Ting Chu, Jin-Ping Li, Shi-Zhong Luo
Publikováno v:
eLife, Vol 13 (2024)
Secreted chemokines form concentration gradients in target tissues to control migratory directions and patterns of immune cells in response to inflammatory stimulation; however, how the gradients are formed is much debated. Heparan sulfate (HS) binds
Externí odkaz:
https://doaj.org/article/1c1d43fda829449ea9510f3353557b9a
Autor:
Xiaoxu Zhang, Bixia Hong, Peng Wei, Pengfei Pei, Haifeng Xu, Long Chen, Yigang Tong, Jialin Chen, Shi-Zhong Luo, Huahao Fan, Chengzhi He
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2658-2669 (2022)
The binding of the receptor binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein onto human angiotensin-converting enzyme 2 (ACE2) is considered as the first step for the virus to adhere onto the host cel
Externí odkaz:
https://doaj.org/article/08ca0d9aa0a944baa03e9caf71ce3433
Autor:
Song Xue, Fan Zhou, Tian Zhao, Huimin Zhao, Xuewei Wang, Long Chen, Jin-ping Li, Shi-Zhong Luo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Liquid-liquid phase separation (LLPS) is reported to occur in the intracellular environment. Here the authors show that heparan sulphate serves as a platform for basic fibroblast growth factor to undergo LLPS on the cell surface, therefore facilitati
Externí odkaz:
https://doaj.org/article/1b32ea87b6fa40e0a2e9e73c0d921421
Autor:
Xiufang Ding, Yue Wang, Sida Zhang, Ruihua Zhang, Dong Chen, Long Chen, Yu Zhang, Shi-Zhong Luo, Jianfu Xu, Chengxin Pei
Publikováno v:
Marine Drugs, Vol 21, Iss 4, p 229 (2023)
Chronic pain is one of the most prevalent health problems worldwide. An alternative to suppress or alleviate chronic pain is the use of peptide drugs that block N-type Ca2+ channels (Cav2.2), such as ω-conotoxin MVIIA. Nevertheless, the narrow thera
Externí odkaz:
https://doaj.org/article/ac8936ae7e154a6991b1395b4473264b
Publikováno v:
ACS Omega, Vol 4, Iss 27, Pp 22562-22573 (2019)
Externí odkaz:
https://doaj.org/article/fa3081d46df04da499833eabe2a60c8f
Publikováno v:
Chemical Biology & Drug Design. 101:1406-1415
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35e95c80878e1244a32ecf111e88af8d
https://doi.org/10.1111/cbdd.14223
https://doi.org/10.1111/cbdd.14223
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
Many proteins and peptides have been identified to effectively and specifically bind on certain surfaces such as silica, polystyrene and titanium dioxide. It is of great interest, in many areas such as enzyme immobilization, surface functionalization
Externí odkaz:
https://doaj.org/article/b72d073a23b54c68bfe1c90364188617
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007777 (2020)
The co-localization of Cluster-of-Differentiation-44 protein (CD44) and cytoplasmic adaptors in specific membrane environments is crucial for cell adhesion and migration. The process is controlled by two different pathways: On the one hand palmitoyla
Externí odkaz:
https://doaj.org/article/77bd81a0a24246b585b71d6ecc82519e
Publikováno v:
International Journal of Biological Macromolecules. 222:207-216
Liquid-liquid phase separation (LLPS) drives the formation of extensive membrane-less compartments to regulate various cellular biological activities both physiologically and pathologically. It has been widely accepted that LLPS is closely related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de9fa461bdf46bf8428bc0acde555ac0
https://doi.org/10.1016/j.ijbiomac.2022.09.087
https://doi.org/10.1016/j.ijbiomac.2022.09.087