Zobrazeno 1 - 10
of 244
pro vyhledávání: '"Shi Yuan Cheng"'
Autor:
Rebeca Piatniczka Iglesia, Mariana Brandão Prado, Rodrigo Nunes Alves, Maria Isabel Melo Escobar, Camila Felix de Lima Fernandes, Ailine Cibele dos Santos Fortes, Maria Clara da Silva Souza, Jacqueline Marcia Boccacino, Giovanni Cangiano, Samuel Ribeiro Soares, João Pedro Alves de Araújo, Deanna Marie Tiek, Anshika Goenka, Xiao Song, Jack Ryan Keady, Bo Hu, Shi Yuan Cheng, Marilene Hohmuth Lopes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Non-canonical secretion pathways, collectively known as unconventional protein secretion (UPS), are alternative secretory mechanisms usually associated with stress-inducing conditions. UPS allows proteins that lack a signal peptide to be secreted, av
Externí odkaz:
https://doaj.org/article/fddc906a16cc494480a52d4a46e716e5
Autor:
Chenxin Xu, Guoyu Chen, Bo Yu, Bowen Sun, Yingwen Zhang, Mingda Zhang, Yi Yang, Yichuan Xiao, Shi‐Yuan Cheng, Yanxin Li, Haizhong Feng
Publikováno v:
Advanced Science, Vol 11, Iss 29, Pp n/a-n/a (2024)
Abstract The factors driving glioma progression remain poorly understood. Here, the epigenetic regulator TRIM24 is identified as a driver of glioma progression, where TRIM24 overexpression promotes HRasV12 anaplastic astrocytoma (AA) progression into
Externí odkaz:
https://doaj.org/article/4533c20a70e64f66876871ae4421263b
Autor:
Chang Zeng, Xiao Song, Zhou Zhang, Qinyun Cai, Jiajun Cai, Craig Horbinski, Bo Hu, Shi-Yuan Cheng, Wei Zhang
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-15 (2023)
Abstract Background Grade 4 glioma is the most aggressive and currently incurable brain tumor with a median survival of one year in adult patients. Elucidating novel transcriptomic and epigenetic contributors to the molecular heterogeneity underlying
Externí odkaz:
https://doaj.org/article/12fb1d98f7474f1cad3977ea8c6f8f53
Akademický článek
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Autor:
Bo Yu, Fei Luo, Bowen Sun, Wenxue Liu, Qiqi Shi, Shi‐Yuan Cheng, Ceshi Chen, Guoqiang Chen, Yanxin Li, Haizhong Feng
Publikováno v:
Advanced Science, Vol 8, Iss 20, Pp n/a-n/a (2021)
Abstract Aberrant SMAD3 activation has been implicated as a driving event in cancer metastasis, yet the underlying mechanisms are still elusive. Here, SMAD3 is identified as a nonhistone substrate of lysine acetyltransferase 6A (KAT6A). The acetylati
Externí odkaz:
https://doaj.org/article/d5df2d22198e44d2aa076247c8e88d98
Autor:
Anshika Goenka, Deanna Marie Tiek, Xiao Song, Rebeca Piatniczka Iglesia, Minghui Lu, Bo Hu, Shi-Yuan Cheng
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 2031 (2022)
For decades, research in cancer biology has been focused on the protein-coding fraction of the human genome. However, with the discovery of non-coding RNAs (ncRNAs), it has become known that these entities not only function in numerous fundamental li
Externí odkaz:
https://doaj.org/article/b3234c0f15e645fb94f7a538ebc02cfb
Publikováno v:
Advanced Optical Materials; 4/4/2024, Vol. 12 Issue 10, p1-8, 8p
Autor:
Yinfang Wang, Yanli Hou, Weiwei Zhang, Angel A. Alvarez, Yongrui Bai, Bo Hu, Shi-Yuan Cheng, Kun Yang, Yanxin Li, Haizhong Feng
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Abstract Background Ionizing radiation (IR) therapy is the standard first-line treatment for newly diagnosed patients with glioblastoma (GBM), the most common and malignant primary brain tumor. However, the effects of IR are limited due to the aberra
Externí odkaz:
https://doaj.org/article/81c67ce5a8be41efba0d8c2f015632df
Autor:
Rajendra P. Pangeni, Zhou Zhang, Angel A. Alvarez, Xuechao Wan, Namratha Sastry, Songjian Lu, Taiping Shi, Tianzhi Huang, Charles X. Lei, C. David James, John A. Kessler, Cameron W. Brennan, Ichiro Nakano, Xinghua Lu, Bo Hu, Wei Zhang, Shi-Yuan Cheng
Publikováno v:
Epigenetics, Vol 13, Iss 4, Pp 432-448 (2018)
Glioma stem cells (GSCs), a subpopulation of tumor cells, contribute to tumor heterogeneity and therapy resistance. Gene expression profiling classified glioblastoma (GBM) and GSCs into four transcriptomically-defined subtypes. Here, we determined th
Externí odkaz:
https://doaj.org/article/9f203d1a69c64cac8045dc5a3fdc5f92
Autor:
Leonidas C. Platanias, C. David James, Ramana V. Davuluri, Craig Horbinski, Ichiro Nakano, Shi-Yuan Cheng, Stewart Goldman, Angel A. Alvarez, Jessica Clymer, Ahmet Dirim Arslan, Yingtao Bi, Hridi Hussain, Lisa P. Magnusson, Kristen Alley, Frank D. Eckerdt, Jonathan B. Bell
Supplementary materials and methods for ALDEFLUOR assay and CD44 staining and data showing that patient-derived GSCs are enriched for ALDH+ cells and express CD44.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785a01ca791720334b4a42e4cfc7aca6
https://doi.org/10.1158/1541-7786.22514899
https://doi.org/10.1158/1541-7786.22514899