Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shi Nai Lee"'
Autor:
Jonghwa Won, Hyun-Soo Cho, Dong Geon Kim, Heekyoung Yang, Do-Hyun Nam, Yeup Yoon, Yeon-Gil Kim, Se-Ho Kim, Kwang-Won Hong, YingJin Kang, Kuglae Kim, Ki Hwan Chang, Kyuhyun Lee, Tae Wook Park, Shi-Nai Lee, Jae-Chul Lee, Hyung-Suk Hur, Eun Hee Lee, Minkyu Hur, Min-Soo Kim, Jiho Yoo, Yangmi Lim
Supplementary Figure 2. The EGFR-GC1118 interaction is not disrupted by excess amounts of high- or low-affinity EGFR ligands. The indicated colorectal cancer cell lines were pre-incubated with 0.1 ug/ml of cetuximab or GC1118 for 2 h prior to the add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725f884ad46d30da06419018eeec1d81
https://doi.org/10.1158/1535-7163.22503043
https://doi.org/10.1158/1535-7163.22503043
Autor:
Jonghwa Won, Hyun-Soo Cho, Dong Geon Kim, Heekyoung Yang, Do-Hyun Nam, Yeup Yoon, Yeon-Gil Kim, Se-Ho Kim, Kwang-Won Hong, YingJin Kang, Kuglae Kim, Ki Hwan Chang, Kyuhyun Lee, Tae Wook Park, Shi-Nai Lee, Jae-Chul Lee, Hyung-Suk Hur, Eun Hee Lee, Minkyu Hur, Min-Soo Kim, Jiho Yoo, Yangmi Lim
Supplementary Figure 1. Kinetic binding interactions between GC1118 and EGFR as analyzed by SPR. SPR sensorgrams were obtained from injections of (A) GC1118 or (B) cetuximab over an EGFR-immobilized surface at a flow rate of 30 µl/min. The results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c649a0a3bacb6dfcc106d8d9e853e5
https://doi.org/10.1158/1535-7163.22503046
https://doi.org/10.1158/1535-7163.22503046
Autor:
Jonghwa Won, Hyun-Soo Cho, Dong Geon Kim, Heekyoung Yang, Do-Hyun Nam, Yeup Yoon, Yeon-Gil Kim, Se-Ho Kim, Kwang-Won Hong, YingJin Kang, Kuglae Kim, Ki Hwan Chang, Kyuhyun Lee, Tae Wook Park, Shi-Nai Lee, Jae-Chul Lee, Hyung-Suk Hur, Eun Hee Lee, Minkyu Hur, Min-Soo Kim, Jiho Yoo, Yangmi Lim
Supplementary Table 1. X-ray data collection and refinement statistics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b7dae88c660f0113a5814ad11b8dd2f
https://doi.org/10.1158/1535-7163.22503037.v1
https://doi.org/10.1158/1535-7163.22503037.v1
Autor:
Jonghwa Won, Hyun-Soo Cho, Dong Geon Kim, Heekyoung Yang, Do-Hyun Nam, Yeup Yoon, Yeon-Gil Kim, Se-Ho Kim, Kwang-Won Hong, YingJin Kang, Kuglae Kim, Ki Hwan Chang, Kyuhyun Lee, Tae Wook Park, Shi-Nai Lee, Jae-Chul Lee, Hyung-Suk Hur, Eun Hee Lee, Minkyu Hur, Min-Soo Kim, Jiho Yoo, Yangmi Lim
Surface plasmon resonance (SPR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b986e8555bae1ac03b9cf184edfa9b
https://doi.org/10.1158/1535-7163.22503040
https://doi.org/10.1158/1535-7163.22503040
Publikováno v:
Blood. 138:2234-2234
Acute myeloid leukemia (AML) is a disease with high incidence of relapse that is originated and maintained from leukemia stem cells (LSCs). Expression of C-type lectin-like molecule-1 (CLL-1; also known as CLEC12A, c-type lectin domain family 12 memb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cca854033b1f59d3c5a3290feea996ef
https://doi.org/10.1182/blood-2021-145274
https://doi.org/10.1182/blood-2021-145274
Autor:
Jiho Yoo, Min Soo Kim, Yeup Yoon, Tae Wook Park, Jonghwa Won, Yangmi Lim, Kwang Won Hong, Jae-Chul Lee, Yeon Gil Kim, Minkyu Hur, Do-Hyun Nam, Shi Nai Lee, Eun-Hee Lee, Se-Ho Kim, Donggeon Kim, Kyuhyun Lee, Hyung Suk Hur, Kuglae Kim, Yingjin Kang, Ki Hwan Chang, Hyun Soo Cho, Heekyoung Yang
Publikováno v:
Molecular Cancer Therapeutics. 15:251-263
The EGFR-targeted monoclonal antibodies are a valid therapeutic strategy for patients with metastatic colorectal cancer (mCRC). However, only a small subset of mCRC patients has therapeutic benefits and there are high demands for EGFR therapeutics wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d320e3c8310b2bba6b7c84a297fe0e
https://doi.org/10.1158/1535-7163.mct-15-0679
https://doi.org/10.1158/1535-7163.mct-15-0679
Autor:
S.H. Park, Joonghyun Ahn, Young-Ae Park, H.K. Ahn, Shi-Nai Lee, Ji-Youn Kim, Seung Hyup Hyun, Yunjoo Im
Publikováno v:
Annals of Oncology. 30:v135
Background Metabolic tumor volume(MTV) measured by (18)F-fluorodeoxyglucose positron emission tomography/computed tomography(FDG PET/CT) was correlated with prognosis in various cancers. The aim of this study was to investigate the prognostic value o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9046f0d4f9f3b3e464729d267a30a242
https://doi.org/10.1093/annonc/mdz242.064
https://doi.org/10.1093/annonc/mdz242.064
Publikováno v:
Annals of Oncology. 30:v766
Background Cancer of unknown primary (CUP) consists of diverse histology types of cancer and have shown poor prognosis. In the era of precision medicine, next-generation sequencing (NGS) may contribute new therapeutic target which could improve treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea68c6c9c356659dc220c639f0e40bc3
https://doi.org/10.1093/annonc/mdz268.015
https://doi.org/10.1093/annonc/mdz268.015
Autor:
Shi-Nai Lee, hee Lee Dae, Jonghwa Won, Eun Hee Lee, Jae-Chul Lee, Cheul Oh Sang, Jun Cho Hyung, Yangmi Lim, Minkyu Hur, Lim Kim Jung
Publikováno v:
Annals of Oncology. 28:iii134-iii135
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d03d482ef58aea889dd10836f9ca36
https://doi.org/10.1093/annonc/mdx261.377
https://doi.org/10.1093/annonc/mdx261.377
Autor:
Hyun-Jung Cho, Kyuhyun Lee, Jonghwa Won, Eun Hee Lee, Yangmi Lim, Minkyu Hur, Shi-Nai Lee, Jae-Chul Lee, Sujeong Kim
Publikováno v:
Cancer Research. 76:LB-114
Purpose: Anti-epidermal growth factor receptor (EGFR) antibodies such as cetuximab and panitumumab are widely used to treat patients with metastatic colorectal cancer (mCRC). However, patients eventually develop resistance to these drugs, which is on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5d71e533ba9f2566a368402ce3219f9
https://doi.org/10.1158/1538-7445.am2016-lb-114
https://doi.org/10.1158/1538-7445.am2016-lb-114