Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Shi Chung Ng"'
Autor:
Christin Tse, Saul H. Rosenberg, Steve W. Elmore, Stephen W. Fesik, Shi-Chung Ng, Robert B. Warner, Jun Chen, Aparna V. Sarthy, Susan E. Morgan-Lappe, Mark G. Anderson, Xiufen Yang, Stephen K. Tahir
Supplementary Tables 1-2 from Influence of Bcl-2 Family Members on the Cellular Response of Small-Cell Lung Cancer Cell Lines to ABT-737
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1884c3270dca0986922fff3eb41b528d
https://doi.org/10.1158/0008-5472.22366922
https://doi.org/10.1158/0008-5472.22366922
Autor:
Christin Tse, Saul H. Rosenberg, Steve W. Elmore, Stephen W. Fesik, Shi-Chung Ng, Robert B. Warner, Jun Chen, Aparna V. Sarthy, Susan E. Morgan-Lappe, Mark G. Anderson, Xiufen Yang, Stephen K. Tahir
ABT-737 is a novel and potent Bcl-2 antagonist with single-agent activity against small-cell lung cancer (SCLC) cell lines. Here, we evaluated the contribution of Bcl-2 family members to the in vitro cellular response of several SCLC cell lines to AB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::886e68cc395eb08b7ca494cd35ebebce
https://doi.org/10.1158/0008-5472.c.6495347
https://doi.org/10.1158/0008-5472.c.6495347
Supplementary Table 1 from Bexarotene (LGD1069, Targretin), a Selective Retinoid X Receptor Agonist, Prevents and Reverses Gemcitabine Resistance in NSCLC Cells by Modulating Gene Amplification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c33d85ffdf3b5433b5d78231725c53
https://doi.org/10.1158/0008-5472.22370942.v1
https://doi.org/10.1158/0008-5472.22370942.v1
Supplementary Figure 1 from Bexarotene (LGD1069, Targretin), a Selective Retinoid X Receptor Agonist, Prevents and Reverses Gemcitabine Resistance in NSCLC Cells by Modulating Gene Amplification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed3abf46a60c5b09f5501b65c1c6d39
https://doi.org/10.1158/0008-5472.22370945
https://doi.org/10.1158/0008-5472.22370945
Autor:
Yan Luo, Shayna K. Rockow-Magnone, Paul E. Kroeger, Leigh Frost, Zehan Chen, Edward K.-H. Han, Shi-Chung Ng, Robert L. Simmer, Vincent L. Giranda
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 5, Pp 411-419 (2001)
Checkpoint kinase 1 (Chki) is a checkpoint gene that is activated after DNA damage. It phosphorylates and inactivates the Cdc2 activating phosphatase Cdc25C. This in turn inactivates Cdc2, which leads to G2/M arrest. We report that blocking Chki expr
Externí odkaz:
https://doaj.org/article/7121327b51a74cf29e5c0cdb49dae0dc
Autor:
Xuesong Liu, Yan Shi, Edward K.-H. Han, Zehan Chen, Saul H. Rosenberg, Vincent L. Giranda, Yan Luo, Shi-Chung Ng
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 4, Pp 278-286 (2001)
The serine/threonine kinases, Akti/PKBα, Akt2/PKBβ, and Akt3/PKBγ, play a critical role in preventing cancer cells from undergoing apoptosis. However, the function of individual Akt isoforms in the tumorigenicity of cancer cells is still not well
Externí odkaz:
https://doaj.org/article/1259fe7cacc64fdead680d919595b6a7
Publikováno v:
BioTechniques, Vol 29, Iss 1, Pp 156-160 (2000)
We have developed a rapid [3H] colchicine competition-binding scintillation proximity assay (SPA) to evaluate antimitotic compounds that bind to the colchicine-binding site on tubulin. The premise of our assay is that compounds will compete with radi
Externí odkaz:
https://doaj.org/article/09710dc5545f42398e97d82ebc886ac7
Autor:
Jun Chen, Wei Wu, Stephen K. Tahir, Paul E. Kroeger, Saul H. Rosenberg, Lex M. Cowsert, Frank Bennett, Stanislaw Krajewski, Maryla Krajewska, Kate Welsh, John C. Reed, Shi-Chung Ng
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 2, Iss 3, Pp 235-241 (2000)
Survivin, a member of the inhibitor of apoptosis protein (IAP) family, is detected in most common human cancers but not in adjacent normal cells. Previous studies suggest that survivin associates with the mitotic spindle and directly inhibits caspase
Externí odkaz:
https://doaj.org/article/59fbb30bc5034417a9a1b3c18c1b0f2f
Autor:
Wang Shen, Fakhoury, Stephen, Donner, Greg, Henry, Kenneth, Lee, Jang, Haichao Zhang, Cohen, Jerry, Warner, Robert, Saeed, Badr, Cherian, Sajeev, Tahir, Stephen, Kovar, Peter, Bauch, Joy, Shi-Chung Ng, Marsh, Kennan, Hing Sham, Rosenberg, Saul
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1999 9(5):703-708
Publikováno v:
Analytical Biochemistry. 407:205-210
Parkinson's disease (PD) is a neurodegenerative disease featured by selective loss of substantia nigra neurons. Rotenone administration in animals induces neurodegeneration accompanied by α-synuclein-positive Lewy body-like inclusions, recapturing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e685d903519dfa239b7a78b39335494
https://doi.org/10.1016/j.ab.2010.08.011
https://doi.org/10.1016/j.ab.2010.08.011