Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Shi‑Cang Yu"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Metabolic abnormalities are an important feature of tumours. The glutamine-arginine-proline axis is an important node of cancer metabolism and plays a major role in amino acid metabolism. This axis also acts as a scaffold for the synthesis of other n
Externí odkaz:
https://doaj.org/article/88d998c2316f44619b279444c3ce413a
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
High aldehyde dehydrogenase (ALDH) activity is a metabolic feature of adult stem cells and various cancer stem cells (CSCs). The ALDEFLUOR system is currently the most commonly used method for evaluating ALDH enzyme activity in viable cells. This sys
Externí odkaz:
https://doaj.org/article/15390384d2264bcd941d4fe88a73f588
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Acute myeloid leukemia (AML) is a highly heterogeneous hematological malignancy. The bone marrow (BM) microenvironment in AML plays an important role in leukemogenesis, drug resistance and leukemia relapse. In this study, we aimed to identify reliabl
Externí odkaz:
https://doaj.org/article/ba22484ed7674f79b43d5ebfa5a7a41f
Autor:
Federica Francescangeli, Maria Laura De Angelis, Rachele Rossi, Giovanni Sette, Adriana Eramo, Alessandra Boe, Ombretta Guardiola, Tao Tang, Shi-Cang Yu, Gabriella Minchiotti, Ann Zeuner
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Chemotherapy is the mainstay for the treatment of non-small cell lung cancer (NSCLC). However, NSCLC cells are either intrinsically chemoresistant or rapidly develop therapy resistance. Cancer stem cells (CSCs) are widely recognized as the cell popul
Externí odkaz:
https://doaj.org/article/7c7e41a2a4654a0b8288753f8239a4c2
Autor:
Tao Tang, Ze-yu Yang, Di Wang, Xian-yan Yang, Jun Wang, Lin Li, Qian Wen, Lei Gao, Xiu-wu Bian, Shi-cang Yu
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-18 (2020)
Abstract Lysosomes are an important component of the inner membrane system and participate in numerous cell biological processes, such as macromolecular degradation, antigen presentation, intracellular pathogen destruction, plasma membrane repair, ex
Externí odkaz:
https://doaj.org/article/b9bdf01a4611484b84ba433137bf949c
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-13 (2020)
Abstract Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor receptor 2 (HER-2), has clinical features that include high
Externí odkaz:
https://doaj.org/article/be95e0ec751e47caba9c7a2a68721490
Autor:
Yu Shi, Yi-Fang Ping, Wenchao Zhou, Zhi-Cheng He, Cong Chen, Bai-Shi-Jiao Bian, Lin Zhang, Lu Chen, Xun Lan, Xian-Chao Zhang, Kai Zhou, Qing Liu, Hua Long, Ti-Wei Fu, Xiao-Ning Zhang, Mian-Fu Cao, Zhi Huang, Xiaoguang Fang, Xiuxing Wang, Hua Feng, Xiao-Hong Yao, Shi-Cang Yu, You-Hong Cui, Xia Zhang, Jeremy N Rich, Shideng Bao, Xiu-Wu Bian
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Tumour-associated macrophages (TAMs) facilitate malignant growth of glioblastoma (GBM). Here, the authors show that TAMs support glioma stem cell renewal via paracrine signalling to the pleiotrophin receptor PTPRZ1 and that blocking this axis results
Externí odkaz:
https://doaj.org/article/fc10d4b4ab8a4e3cb428bc0e73382649
Autor:
Xiao-Jun Yang, Wei Cui, Ai Gu, Chuan Xu, Shi-Cang Yu, Ting-Ting Li, You-Hong Cui, Xia Zhang, Xiu-Wu Bian
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61801 (2013)
Invasion and metastasis of solid tumors are the major causes of death in cancer patients. Cancer stem cells (CSCs) constitute a small fraction of tumor cell population, but play a critical role in tumor invasion and metastasis. The xenograft of tumor
Externí odkaz:
https://doaj.org/article/65ee88cb76c7461bbc794dcc16127072
Publikováno v:
Cellular Oncology. 46:465-480
Publikováno v:
Trends in Cell Biology.