Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Shi‐meng Guo"'
Autor:
Yi-Ran Zhang, Ying Yin, Shi-Meng Guo, Yu-Fan Wang, Guang-Nian Zhao, Dong-Mei Ji, Li-Quan Zhou
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract With increasingly used assisted reproductive technology (ART), the acquisition of high-quality oocytes and early embryos has become the focus of much attention. Studies in mice have found that the transition of chromatin conformation from no
Externí odkaz:
https://doaj.org/article/7b7def83aba946a9991f821e562efc72
Autor:
Shi-meng Guo, Xing-ping Liu, Qing Tian, Cai-feng Fei, Yi-ran Zhang, Zhi-ming Li, Ying Yin, Ximiao He, Li-quan Zhou
Publikováno v:
Reproductive Biology and Endocrinology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background Enhancer of zeste homologue 2 (EZH2), the core member of polycomb repressive complex 2 (PRC2), has multiple splicing modes and performs various physiological functions. However, function and mechanism of alternative splicing at Ez
Externí odkaz:
https://doaj.org/article/7ea574d08f9f4c94ba5bbe090acad7e9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Dynamic-related protein 1 (DRP1) is a key protein of mitochondrial fission. In this study, we found that inhibition of activity of DRP1 led to increased levels of cleavage embryo genes in mouse embryonic stem cells (mESCs), which might reflect a tran
Externí odkaz:
https://doaj.org/article/e08195c387ca4880bcf38009aee5a2e0
Autor:
Ning‐hua Mei, Shi‐meng Guo, Qi Zhou, Yi‐ran Zhang, Xiao‐zhao Liu, Ying Yin, Ximiao He, Jing Yang, Tai‐lang Yin, Li‐quan Zhou
Publikováno v:
Advanced Science, Vol 10, Iss 12, Pp n/a-n/a (2023)
Abstract Significantly decreased H3K4 methylation in oocytes from aged mice indicates the important roles of H3K4 methylation in female reproduction. However, how H3K4 methylation regulates oocyte development remains largely unexplored. In this study
Externí odkaz:
https://doaj.org/article/065bb0620036479691131bf444ac6f21
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 5, Pp 307-312 (2021)
During mammalian preimplantation development, stimulation of zygotic genome activation (ZGA) and transposable elements (TEs) shapes totipotency profiling. A rare mouse embryonic stem cells (mESCs) subpopulation is capable of transiently entering a st
Externí odkaz:
https://doaj.org/article/885ba58db85f4f68bc738e41d85e3f7f
Publikováno v:
Reproductive Biology and Endocrinology, Vol 19, Iss 1, Pp 1-7 (2021)
Abstract Background After fertilization, the fusion of gametes results in the formation of totipotent zygote. During sperm-egg fusion, maternal factors participate in parental chromatin remodeling. H3.3 is a histone H3 variant that plays essential ro
Externí odkaz:
https://doaj.org/article/f061bbdc36354beb8ff5f21707f899d9
Transcription factor OTX2 silences the expression of cleavage embryo genes and transposable elements
Publikováno v:
The Journal of Reproduction and Development, Vol 67, Iss 3, Pp 223-228 (2021)
Upon mammalian fertilization, zygotic genome activation (ZGA) and activation of transposable elements (TEs) occur in early embryos to establish totipotency and support embryogenesis. However, the molecular mechanisms controlling the expression of the
Externí odkaz:
https://doaj.org/article/dd78091fed644b70926e8cfaa22328f3
Autor:
Yu Tian, Kai-yi Sun, Tian-qing Meng, Zhen Ye, Shi-meng Guo, Zhi-ming Li, Cheng-liang Xiong, Ying Yin, Hong-gang Li, Li-quan Zhou
Publikováno v:
Frontiers in Nutrition, Vol 8 (2021)
Coronavirus disease 2019 (COVID-19) has infected over 124 million people worldwide. In addition to the development of therapeutics and vaccines, the evaluation of the sequelae in recovered patients is also important. Recent studies have indicated tha
Externí odkaz:
https://doaj.org/article/67712e87b1214feca37944331b329032
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-20
The immature germinal vesicle (GV) oocytes proceed through metaphase I (MI) division, extrude the first polar body, and become mature metaphase II (MII) oocytes for fertilization which is followed by preimplantation and postimplantation development u
Publikováno v:
Environmental Toxicology. 37:1563-1574
N,N-dimethylformamide (DMF) is a widely-used solvent for the synthesis of synthetic fibers such as polyacrylonitrile fiber, and can also be used to make medicine. Although this organic solvent has multipurpose applications, its biological toxicity ca