Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Sheyla, Finkner"'
Autor:
Jared S. Bee, Yu Zhang, Sheyla Finkner, Kristin O'Berry, Akanksha Kaushal, Megan Kuhn Phillippi, Roberto A. DePaz, Keith Webber, Tristan Marshall
Publikováno v:
Journal of Pharmaceutical Sciences. 111:1868-1878
Autor:
Jared S, Bee, Yu, Zhang, Sheyla, Finkner, Kristin, O'Berry, Akanksha, Kaushal, Megan Kuhn, Phillippi, Roberto A, DePaz, Keith, Webber, Tristan, Marshall
Publikováno v:
Journal of pharmaceutical sciences. 111(7)
Gene therapies delivered using adeno-associated virus (AAV) vectors are showing promise for many diseases. Frozen AAV drug products are exposed to freeze-thaw (F/T) cycles during manufacturing, storage, and distribution. In this work we studied the m
Autor:
Jared S. Bee, Yu (Zoe) Zhang, Megan Kuhn Phillippi, Sheyla Finkner, Tesfu Mezghebe, Keith Webber, Win Den Cheung, Tristan Marshall
Publikováno v:
Journal of pharmaceutical sciences. 111(5)
There are an increasing number of clinical studies evaluating different adeno-associated virus (AAV) serotypes as vectors for gene therapy. Long-term frozen storage can maximize the stability of AAV. Freeze-thaw (F/T) cycles and exposures to room tem