Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sheung Kwan Lam"'
Autor:
Siva Charan Devanaboyina, Peng Li, Edward L. LaGory, Carrie Poon-Andersen, Kevin D. Cook, Marcus Soto, Zhe Wang, Khue Dang, Craig Uyeda, Ryan B. Case, Veena A. Thomas, Ronya Primack, Manuel Ponce, Mei Di, Brian Ouyang, Joelle Kaner, Sheung Kwan Lam, Mina Mostafavi
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Targeting antigens with antibodies exhibiting pH/Ca2+-dependent binding against an antigen is an attractive strategy to mitigate target-mediated disposition and antigen buffering. Studies have reported improved serum exposure of antibodies exhibiting
Externí odkaz:
https://doaj.org/article/e01cdf9351b64b009ab7296a2022f247
Publikováno v:
BBA Advances, Vol 1, Iss , Pp 100022- (2021)
The fundamental importance of membrane protein (MP) targets in central biological and cellular events has driven a marked increase in the use of membrane mimetics for exploring these proteins as therapeutic targets. The main challenge associated with
Externí odkaz:
https://doaj.org/article/ec1e472128ac483db74b592db91ec414
Autor:
Yi Cai, Xiaohong Zhuang, Junqi Wang, Xiangfeng Wang, Sheung Kwan Lam, Liwen Jiang, Caiji Gao, Hao Wang
Publikováno v:
Traffic. 13:1023-1040
In plant cells, how integral plasma membrane (PM) proteins are degraded in a cargo ubiquitination-independent manner remains elusive. Here, we studied the degradative pathway of two plant PM proteins: AtLRR84A, a type I integral membrane protein belo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2037d7233e9ada914e8ae125d3f4da12
https://doi.org/10.1111/j.1600-0854.2012.01360.x
https://doi.org/10.1111/j.1600-0854.2012.01360.x
Autor:
Melody Wan Yan San, Liwen Jiang, Yi Cai, Yu Ding, Peter Pimpl, Tianran Jia, Sheung Kwan Lam, Caiji Gao
Publikováno v:
The Plant Journal. 65:882-896
How polytopic plasma membrane (PM) proteins reach their destination in plant cells remains elusive. Using transgenic tobacco BY-2 cells, we previously showed that the rice secretory carrier membrane protein 1 (SCAMP1), an integral membrane protein wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::140be4fdd1dc03ff5caa4365c7d9f018
https://doi.org/10.1111/j.1365-313x.2010.04469.x
https://doi.org/10.1111/j.1365-313x.2010.04469.x
Autor:
Brian R. Johnson, Sheung Kwan Lam
Publikováno v:
BioScience. 60:879-885
Self-organization is sometimes presented as an alternative to natural selection as the primary mechanism underlying the evolution of function in biological systems. Here we argue that although self-organization is one of selection's fundamental tools
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eb287ecb7d55d401f4cd2ba8bb71378
https://doi.org/10.1525/bio.2010.60.11.4
https://doi.org/10.1525/bio.2010.60.11.4
Publikováno v:
Journal of Experimental Botany
Wortmannin, a specific inhibitor of phosphatidyl-inositol 3-kinase, is a useful tool for studying protein trafficking and identifying organelles in the plant secretory and endocytic pathways. It has recently been demonstrated that wortmannin at 16.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3850589f2d9972380cf05010aa6050b8
https://doi.org/10.1093/jxb/erp136
https://doi.org/10.1093/jxb/erp136
Publikováno v:
Journal of Plant Biology. 52:1-9
The plant secretory and endocytic pathways consist of several functionally distinct membrane-bounded compartments. The ultra structures of the endoplasmic reticulum, the Golgi apparatus, and central vacuoles have been well characterized via tradition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef4379f204810b44cc9a18edab8e7329
https://doi.org/10.1007/s12374-008-9000-z
https://doi.org/10.1007/s12374-008-9000-z
Publikováno v:
Journal of Integrative Plant Biology. 49:1119-1128
Prevacuolar compartments (PVCs) and endosomal compartments are membrane-bound organelles mediating protein traffic to vacuoles in the secretory and endocytic pathways of plant cells. Over the years, great progress has been made towards our understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::560ba4655a4768b60fef20337a75f018
https://doi.org/10.1111/j.1672-9072.2007.00517.x
https://doi.org/10.1111/j.1672-9072.2007.00517.x
Autor:
Xiangfeng Wang, Sheung Kwan Lam, Caiji Gao, Yonglun Zeng, Ming Luo, Yong Cui, Kam-Bo Wong, Ching Man Lai, Randy Schekman, Kin Pan Chung, Liwen Jiang, Baiying Li
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 112, iss 46
Secretory proteins traffic from endoplasmic reticulum (ER) to Golgi via the coat protein complex II (COPII) vesicle, which consists of five cytosolic components (Sar1, Sec23-24, and Sec13-31). In eukaryotes, COPII transport has diversified due to gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6937b193ac4e584b508c2e4fa4248a64
https://pubmed.ncbi.nlm.nih.gov/26578783
https://pubmed.ncbi.nlm.nih.gov/26578783
Publikováno v:
The Plant cell. 25(11)
Autophagy is a well-defined catabolic mechanism whereby cytoplasmic materials are engulfed into a structure termed the autophagosome. In plants, little is known about the underlying mechanism of autophagosome formation. In this study, we report that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d372ae92cb1bfcf893669500c7c0c3db
https://pubmed.ncbi.nlm.nih.gov/24249832
https://pubmed.ncbi.nlm.nih.gov/24249832