Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Sheu Meei Yu"'
Publikováno v:
Journal of Natural Products. 60:1008-1011
The biological activities of the active principles of two plants in the Moraceae have been investigated. A new prenylflavonoid, australone A (1), and a new triterpenoid, 3 beta-[(m-methoxybenzoyl)oxy]urs-12-en-28-ioc acid (2) were isolated from the r
Publikováno v:
Circulation. 95:1269-1277
Background Abnormal proliferation of vascular smooth muscle cells (VSMC) is a key event in the pathogenesis of atherosclerosis and many vascular diseases. It is known that nitric oxide released from the endothelium participates in the regulation of V
Publikováno v:
Circulation. 94:547-554
Background Catecholamines have been shown to aggravate atherosclerosis in animals and humans, and abnormal proliferation of vascular smooth muscle cells (VSMC) is a key event in the early stage of atherosclerosis. Catecholamines may be involved in su
Publikováno v:
Blood. 87:3758-3767
The effect of A02131–1 [3-(5′-hydroxymethyl-2′-furyl)-1-benzyl thieno (3,2-c)pyrazole], a cGMP-specific phosphodiesterase (PDE) inhibitor, on platelet function was investigated. The compound was found to inhibit the aggregation of and adenosine
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 349:637-643
N-Allylsecoboldine was shown to be the most effective of several boldine derivatives that were tested for their vasorelaxing effect on the rat aorta. In KCl (60 mmol/l) medium, Ca2+ (0.03-3 mmol/l)-induced vasoconstriction was inhibited, concentratio
Publikováno v:
Phytochemistry. 36:785-788
Investigation of the root of Cinnamomum philippinense resulted in the isolation of a new lignan, cinnamophilin, together with three known compounds, meso-dihydroguaiaretic acid, (+)-guaiacin and vallinic acid. Their structures were elucidated by spec
Publikováno v:
European Journal of Pharmacology. 256:85-91
The pharmacological activity of cinnamophilin ((8R,8'S)-4,4'-dihydroxy-3,3'-dimethoxy-7-oxo-8,8'-neolignan), isolated from Cinnamomum philippinense, was studied in isolated rat aorta, guinea-pig trachea and rabbit platelets. Cinnamophilin was found t
Autor:
Shyh-Chyan Chen, Shih-Chieh Chueh, Che-Ming Teng, Feng-Nien Ko, Jun Chen, Chien Chih Chen, Sheu-Meei Yu
Publikováno v:
European Journal of Pharmacology. 252:29-34
The effects of dicentrine, an alpha 1-adrenoceptor antagonist, on human hyperplastic prostates were investigated by radioligand binding and in vitro isometric tension experiments. In human hyperplastic prostates, alpha 1-adrenoceptors were characteri
Publikováno v:
Journal of Biomedical Science. 1:54-60
The vasorelaxing effect of N-benzylsecoboldine on the rat thoracic aorta was investigated, and we also compare it with nifedipine and cromakalim. In high K(+) (60 mM) medium, Ca(2+) (0.03-3 mM)-induced vasoconstriction was inhibited concentration-dep
Publikováno v:
European Journal of Pharmacology. 233:7-12
Thaliporphine (0.1-100 microM) produced sustained, concentration-dependent contraction in isolated rings of rat aorta. Thaliporphine (ED50 = 1.5 +/- 0.5 microM) was less potent than endothelin (ED50 = 3.9 +/- 0.4 nM), but was more potent than Bay K 8