Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shessy Torres Morales"'
Autor:
Lucy Rutten, Maarten Swart, Annemart Koornneef, Pascale Bouchier, Sven Blokland, Ava Sadi, Jarek Juraszek, Aneesh Vijayan, Sonja Schmit-Tillemans, Johan Verspuij, Ying Choi, Chenandly E. Daal, Aditya Perkasa, Shessy Torres Morales, Sebenzile K. Myeni, Marjolein Kikkert, Jeroen Tolboom, Daniëlle van Manen, Harmjan Kuipers, Hanneke Schuitemaker, Roland Zahn, Johannes P. M. Langedijk
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The spike protein (S) of SARS-CoV-2 induces neutralizing antibodies and is the key component of current COVID-19 vaccines. The most efficacious COVID-19 vaccines are genetically-encoded spikes with a double proline substitution in the hinge
Externí odkaz:
https://doaj.org/article/2c5d3e1e3a7e47e1962a95fc294bb57c
Autor:
Sebenzile K. Myeni, Anouk A. Leijs, Peter J. Bredenbeek, Shessy Torres Morales, Marissa E. Linger, Cyrielle Fougeroux, Sophie van Zanen-Gerhardt, Serge A. L. Zander, Adam F. Sander, Marjolein Kikkert
Publikováno v:
Vaccines, Vol 12, Iss 7, p 766 (2024)
The SARS-CoV-2 pandemic and the emergence of novel virus variants have had a dramatic impact on public health and the world economy, underscoring the need for detailed studies that explore the high efficacy of additional vaccines in animal models. In
Externí odkaz:
https://doaj.org/article/d28bc8a871ee4f499192070d34b38ba9
Autor:
Sebenzile K. Myeni, Peter J. Bredenbeek, Robert C. M. Knaap, Tim J. Dalebout, Shessy Torres Morales, Igor A. Sidorov, Marissa E. Linger, Nadia Oreshkova, Sophie van Zanen-Gerhardt, Serge A. L. Zander, Luis Enjuanes, Isabel Sola, Eric J. Snijder, Marjolein Kikkert
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
In this work, authors provide a proof-of-concept study showing that deubiquitinating enzyme inactivation in MERS-CoV leads to attenuation in mice, and protection against a lethal challenge.
Externí odkaz:
https://doaj.org/article/499cce9a22364325b1ef3db166d2a937
Autor:
Linda van Oosten, Jort J. Altenburg, Cyrielle Fougeroux, Corinne Geertsema, Fred van den End, Wendy A. C. Evers, Adrie H. Westphal, Simon Lindhoud, Willy van den Berg, Daan C. Swarts, Laurens Deurhof, Andreas Suhrbier, Thuy T. Le, Shessy Torres Morales, Sebenzile K. Myeni, Marjolein Kikkert, Adam F. Sander, Willem Adriaan de Jongh, Robert Dagil, Morten A. Nielsen, Ali Salanti, Max Søgaard, Timo M. P. Keijzer, Dolf Weijers, Michel H. M. Eppink, René H. Wijffels, Monique M. van Oers, Dirk E. Martens, Gorben P. Pijlman
Publikováno v:
mBio, Vol 12, Iss 5 (2021)
Vaccines pave the way out of the SARS-CoV-2 pandemic. We have developed a virus-like particle (VLP)-based vaccine using the baculovirus-insect cell expression system, a robust production platform known for its scalability, low cost, and safety. Bacul
Externí odkaz:
https://doaj.org/article/9d799f0e15554e7aafc11f877069c7c0
Autor:
Monique M. van Oers, Thuy T. Le, Robert Dagil, Cyrielle Fougeroux, Willy A. M. van den Berg, Marjolein Kikkert, Adam F. Sander, Adrie H. Westphal, Simon Lindhoud, Andreas Suhrbier, Ali Salanti, Willem A. de Jongh, M.H.M. Eppink, Jort J Altenburg, Dolf Weijers, René H. Wijffels, Dirk E. Martens, Corinne Geertsema, Fred van den End, Gorben P. Pijlman, Timo M P Keijzer, Linda van Oosten, Sebenzile K. Myeni, Wendy A. C. Evers, Max Søgaard, Daan C. Swarts, Morten Nielsen, Laurens Deurhof, Shessy Torres Morales
Publikováno v:
mBio
mBio, 12(5)
mBio, Vol 12, Iss 5 (2021)
van Oosten, L, Altenburg, J J, Fougeroux, C, Geertsema, C, van den End, F, Evers, W A C, Westphal, A H, Lindhoud, S, van den Berg, W, Swarts, D C, Deurhof, L, Suhrbier, A, Le, T T, Torres Morales, S, Myeni, S K, Kikkert, M, Sander, A F, de Jongh, W A, Dagil, R, Nielsen, M A, Salanti, A, Søgaard, M, Keijzer, T M P, Weijers, D, Eppink, M H M, Wijffels, R H, van Oers, M M, Martens, D E & Pijlman, G P 2021, ' Two-component nanoparticle vaccine displaying glycosylated spike S1 domain induces neutralizing antibody response against SARS-CoV-2 variants ', mBio, vol. 12, no. 5, e0181321 . https://doi.org/10.1128/mBio.01813-21
mBio, 12(5). AMER SOC MICROBIOLOGY
mBio 12 (2021) 5
mBio, 12(5)
mBio, Vol 12, Iss 5 (2021)
van Oosten, L, Altenburg, J J, Fougeroux, C, Geertsema, C, van den End, F, Evers, W A C, Westphal, A H, Lindhoud, S, van den Berg, W, Swarts, D C, Deurhof, L, Suhrbier, A, Le, T T, Torres Morales, S, Myeni, S K, Kikkert, M, Sander, A F, de Jongh, W A, Dagil, R, Nielsen, M A, Salanti, A, Søgaard, M, Keijzer, T M P, Weijers, D, Eppink, M H M, Wijffels, R H, van Oers, M M, Martens, D E & Pijlman, G P 2021, ' Two-component nanoparticle vaccine displaying glycosylated spike S1 domain induces neutralizing antibody response against SARS-CoV-2 variants ', mBio, vol. 12, no. 5, e0181321 . https://doi.org/10.1128/mBio.01813-21
mBio, 12(5). AMER SOC MICROBIOLOGY
mBio 12 (2021) 5
Vaccines pave the way out of the SARS-CoV-2 pandemic. Besides mRNA and adenoviral vector vaccines, effective protein-based vaccines are needed for immunization against current and emerging variants. We have developed a virus-like particle (VLP)-based