Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Sheryl S. Moy"'
Autor:
George D. Dalton, Stephen K. Siecinski, Viktoriya D. Nikolova, Gary P. Cofer, Kathryn J. Hornburg, Yi Qi, G. Allan Johnson, Yong-Hui Jiang, Sheryl S. Moy, Simon G. Gregory
Publikováno v:
Behavioral and Brain Functions, Vol 20, Iss 1, Pp 1-23 (2024)
Abstract Background Autism Spectrum Disorder (ASD) is a group of neurodevelopmental disorders with higher incidence in males and is characterized by atypical verbal/nonverbal communication, restricted interests that can be accompanied by repetitive b
Externí odkaz:
https://doaj.org/article/3a0dc3d8da37446598bf596a2a78dc61
Publikováno v:
Neurobiology of Stress, Vol 28, Iss , Pp 100589- (2024)
Many stress-related neuropsychiatric disorders display pronounced sex differences in their frequency and clinical symptoms. Glucocorticoids are primary stress hormones that have been implicated in the development of these disorders but whether they c
Externí odkaz:
https://doaj.org/article/e7dd9677251141698fad4c81d5073831
Autor:
Julie C Necarsulmer, Jeremy M Simon, Baggio A Evangelista, Youjun Chen, Xu Tian, Sara Nafees, Ariana B Marquez, Huijun Jiang, Ping Wang, Deepa Ajit, Viktoriya D Nikolova, Kathryn M Harper, J Ashley Ezzell, Feng-Chang Lin, Adriana S Beltran, Sheryl S Moy, Todd J Cohen
Publikováno v:
eLife, Vol 12 (2023)
TDP-43 proteinopathies including frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are neurodegenerative disorders characterized by aggregation and mislocalization of the nucleic acid-binding protein TDP-43 and subseque
Externí odkaz:
https://doaj.org/article/1ef60b65b631406abd7b36cb7384d395
Autor:
Shenée C. Martin, Kathryn K. Joyce, Kathryn M. Harper, Samuel J. Harp, Todd J. Cohen, Sheryl S. Moy, Graham H. Diering
Publikováno v:
Pharmaceuticals, Vol 17, Iss 3, p 319 (2024)
Sleep disruption is an expected component of aging and neurodegenerative conditions, including Alzheimer’s disease (AD). Sleep disruption has been demonstrated as a driver of AD pathology and cognitive decline. Therefore, treatments designed to mai
Externí odkaz:
https://doaj.org/article/7e26de891f7f48d69a3dc5e4560420ae
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
Neurodevelopmental disorders (NDDs) are complex conditions characterized by heterogeneous clinical profiles and symptoms that arise in infancy and childhood. NDDs are often attributed to a complicated interaction between genetic risk and environmenta
Externí odkaz:
https://doaj.org/article/43614a25a06f4d2694b5d170de08c09b
Autor:
Julia S. Lord, Sean M. Gay, Kathryn M. Harper, Viktoriya D. Nikolova, Kirsten M. Smith, Sheryl S. Moy, Graham H. Diering
Publikováno v:
Molecular Autism, Vol 13, Iss 1, Pp 1-19 (2022)
Abstract Background Patients with autism spectrum disorder (ASD) experience high rates of sleep disruption beginning early in life; however, the developmental consequences of this disruption are not understood. We examined sleep behavior and the cons
Externí odkaz:
https://doaj.org/article/c5e745d47c3941baa4b107535e8ce93b
Autor:
Jessica A. Jiménez, Jeremy M. Simon, Wenxin Hu, Sheryl S. Moy, Kathryn M. Harper, Chih-Wei Liu, Kun Lu, Mark J. Zylka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Hundreds of genes have been associated with autism spectrum disorder (ASD), including loss-of-function mutations in chromodomain helicase DNA binding protein 8 (Chd8). Environmental factors also are implicated in autism risk and have the pot
Externí odkaz:
https://doaj.org/article/04768033bf0245a198afb592fc2b8afe
Autor:
R. Oliver Goral, Kathryn M. Harper, Briana J. Bernstein, Sydney A. Fry, Patricia W. Lamb, Sheryl S. Moy, Jesse D. Cushman, Jerrel L. Yakel
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Introduction: Altered signaling or function of acetylcholine (ACh) has been reported in various neurological diseases, including Alzheimer’s disease, Tourette syndrome, epilepsy among others. Many neurons that release ACh also co-transmit the neuro
Externí odkaz:
https://doaj.org/article/37d07ecc33924efab4a32cc003faff10
Autor:
Alexandra Barnett, Emeraghi David, Aaron Rohlman, Viktoriya D. Nikolova, Sheryl S. Moy, Ryan P. Vetreno, Leon G. Coleman
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Epidemiological studies suggest that heavy alcohol use early in life is associated with increased risk for Alzheimer’s disease (AD). However, mechanisms connecting AD with alcohol use have not been identified. Both heavy alcohol use and AD feature
Externí odkaz:
https://doaj.org/article/e5d090a48c06403ab7454b6126522146
Autor:
Hanna Trzeciakiewicz, Deepa Ajit, Jui-Heng Tseng, Youjun Chen, Aditi Ajit, Zarin Tabassum, Rebecca Lobrovich, Claire Peterson, Natallia V. Riddick, Michelle S. Itano, Ashutosh Tripathy, Sheryl S. Moy, Virginia M. Y. Lee, John Q. Trojanowski, David J. Irwin, Todd J. Cohen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
HDAC6 is a tau deacetylase and acetylation of tau inhibits its function and promotes aggregation. Here the authors show that HDAC6 protects against tau accumulation in a mouse model of tauopathy.
Externí odkaz:
https://doaj.org/article/61ab6286279144ac8d59a59cc0805267