Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sheryl L. Carr"'
Publikováno v:
Journal of Thrombosis and Haemostasis. 1:243-249
Thrombin causes platelet activation via multiple pathways, and deficient thrombin generation reduces platelet contractile force (PCF) during clot retraction. We hypothesized that PCF in blood samples from clotting factor-deficient patients would be d
Publikováno v:
Thrombosis Research. 108:161-168
Background: Aprotinin interferes with heparin binding to platelets and decreases blood loss during cardiopulmonary bypass (CPB). Heparin abolishes platelet force during CPB, and the extent of platelet force recovery after protamine administration app
Publikováno v:
Blood Coagulation & Fibrinolysis. 13:193-197
Clot retraction is a thrombin-dependent, platelet-mediated contraction of the cellular clot mass. In this study, the effects of delayed, deficient and inhibited thrombin generation on the development of platelet contractile force (PCF) and clot elast
Autor:
Richard A. McPherson, Nelson L. Bernardo, Erika J. Martin, Anthony J. Minisi, Sheryl L. Carr, Marcus E. Carr, On Topaz
Publikováno v:
Thrombosis and Haemostasis. 86:1087-1093
SummaryPlatelets, a major constituent of thrombus, play a crucial role in the pathogenesis of acute ischemic coronary syndromes. The effect of ultraviolet laser emission on platelets within thrombi is unknown. The effects of increasing levels of lase
Autor:
Sheryl L. Carr, Laxmi Mohanty, Susan J. Hines, Marcus E. Carr, Tamarro L. Taylor, William M. Todd
Publikováno v:
The American Journal of the Medical Sciences. 313:176-181
Although bleeding complications are relatively common in patients with chronic lymphocytic leukemia, they tend to be related to thrombocytopenia or an acquired clotting factor inhibitor. Chronic lymphocytic leukemia-associated thrombocytopenia, which
Autor:
Steven Grant, A J Turner, Marcus E. Carr, Harry D. Bear, Sheryl L. Carr, Paul J. Kostuchenko, Kenneth A Lipshy, Giselle G. Hamad, John D. Roberts, Andrew McFadden
Publikováno v:
Anti-Cancer Drugs. 7:299-306
Bryostatin 1 activates and subsequently down-regulates protein kinase C (PKC) in vitro and has potential use as an immunomodulator and as an anti-cancer agent. Despite extensive examination of its activities in vitro and anti-tumor effects in vivo, p
Publikováno v:
Thrombosis and Haemostasis. 75:674-678
SummaryAlthough snake venom enzymes such as reptilase do not cause viscous metamorphosis, platelet secretion or clot retraction; when batroxobin and calcium are added to citrated blood significant platelet force development occurs. When this batroxob
Publikováno v:
Anti-Cancer Drugs. 6:384-391
Bryostatin 1, a macrocyclic lactone activator of protein kinase C (PKC) currently in phase I evaluation, is a biologic response modifier which exhibits significant antitumor activity in several experimental systems. Clinical trials have been hampered
Publikováno v:
Anesthesia & Analgesia. 80:459-465
Quantitative assessment of platelet dysfunction after cardiopulmonary bypass (CPB) and prediction of excessive microvascular bleeding remain elusive goals. We used a sensitive instrument capable of simultaneously measuring the force generated by plat
Publikováno v:
Thrombosis research. 119(6)
Introduction Uremic bleeding frequently occurs in dialysis patients. Although its mechanism is not well characterized, acquired platelet dysfunction has been implicated in its pathogenesis. Skin bleeding time has been used to characterize platelet dy